PMID- 34499161 OWN - NLM STAT- MEDLINE DCOM- 20211227 LR - 20211227 IS - 1538-6724 (Electronic) IS - 0031-9023 (Linking) VI - 101 IP - 11 DP - 2021 Nov 1 TI - Responsiveness and Minimal Clinically Important Difference of the Brief-BESTest in People With COPD After Pulmonary Rehabilitation. LID - pzab209 [pii] LID - 10.1093/ptj/pzab209 [doi] AB - OBJECTIVE: he Brief-Balance Evaluation Systems Test (Brief-BESTest) is a comprehensive, reliable, and valid balance test that provides valuable information to guide balance training in people with chronic obstructive pulmonary disease (COPD). Its clinical interpretability is, however, currently limited, because cutoff points to identify clinically relevant changes in people with COPD after pulmonary rehabilitation are still lacking. This study aimed to establish the responsiveness and minimal clinically important difference (MCID) for the Brief-BESTest in people with COPD after pulmonary rehabilitation (PR). METHODS: A secondary analysis of data from 2 previous studies was conducted. The modified British Medical Research Council (mMRC) dyspnea scale, the 6-Minute Walk Test (6-MWT), and the Brief-BESTest (0-24 points) were collected in people with COPD pre/post a 12-week PR program including balance training. The MCID was computed using anchor- and distribution-based methods. Changes in the 6-MWT and the mMRC were assessed and used as anchors. The pooled MCID was computed using the arithmetic weighted mean (2/3 anchor- and 1/3 distribution-based methods). RESULTS: Seventy-one people with COPD (69 years [SD = 8]; 76% male; FEV1 = 49.8%predicted [SD = 18%]) were included. There was a significant improvement in the Brief-BESTest after PR (mean difference = 3 points [SD = 3]). Significant correlations were found between the Brief-BESTest and the mMRC (r = -.31) and the 6-MWT (r = .37). The pooled MCID was 3.3 points. CONCLUSION: An improvement of at least 3 points in the Brief-BESTest in people with COPD will enhance the interpretability of PR effects on balance performance of this population and guide tailored interventions. IMPACT: The Brief-BESTest outcome measure is comprehensive, easily administered, and simple to interpret in clinical practice. This study represents a significant contribution toward the clinical interpretation of changes in balance in people with COPD following PR. CI - (c) The Author(s) 2021. Published by Oxford University Press on behalf of the American Physical Therapy Association. All rights reserved. For permissions, please email: journals.permissions@oup.com. FAU - Paixao, Catia AU - Paixao C AD - Lab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal. AD - iBiMED-Institute of Biomedicine, University of Aveiro, Aveiro, Portugal. AD - Department of Medical Sciences, University of Aveiro, Aveiro, Portugal. FAU - Rebelo, Patricia AU - Rebelo P AD - Lab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal. AD - iBiMED-Institute of Biomedicine, University of Aveiro, Aveiro, Portugal. AD - Department of Medical Sciences, University of Aveiro, Aveiro, Portugal. FAU - Oliveira, Ana AU - Oliveira A AD - Lab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal. AD - School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. AD - West Park Healthcare Centre, Toronto, Ontario, Canada. FAU - Jacome, Cristina AU - Jacome C AD - CINTESIS-Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal. AD - MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal. FAU - Cruz, Joana AU - Cruz J AD - Lab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal. AD - ciTechCare-Center for Innovative Care and Health Technology, School of Health Sciences (ESSLei), Polytechnic of Leiria, Leiria, Portugal. FAU - Martins, Vitoria AU - Martins V AD - Pulmonology Department, Hospital Distrital da Figueira da Foz, Figueira da Foz, Portugal. FAU - Simao, Paula AU - Simao P AD - Pulmonology Department, Unidade Local de Saude de Matosinhos, Matosinhos, Portugal. FAU - Marques, Alda AU - Marques A AD - Lab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal. AD - iBiMED-Institute of Biomedicine, University of Aveiro, Aveiro, Portugal. LA - eng SI - ClinicalTrials.gov/NCT03799666 PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Phys Ther JT - Physical therapy JID - 0022623 SB - IM MH - Aged MH - Female MH - Humans MH - Male MH - Middle Aged MH - Minimal Clinically Important Difference MH - Outcome Assessment, Health Care/*standards MH - Postural Balance/*physiology MH - Pulmonary Disease, Chronic Obstructive/*physiopathology/*therapy MH - Respiratory Therapy/*methods MH - Walk Test OTO - NOTNLM OT - Balance OT - Brief-BESTest OT - COPD OT - Minimal Clinically Important Difference OT - Pulmonary Rehabilitation OT - Responsiveness EDAT- 2021/09/10 06:00 MHDA- 2021/12/28 06:00 CRDT- 2021/09/09 12:24 PHST- 2021/01/14 00:00 [received] PHST- 2021/05/21 00:00 [revised] PHST- 2021/07/11 00:00 [accepted] PHST- 2021/09/10 06:00 [pubmed] PHST- 2021/12/28 06:00 [medline] PHST- 2021/09/09 12:24 [entrez] AID - 6365141 [pii] AID - 10.1093/ptj/pzab209 [doi] PST - ppublish SO - Phys Ther. 2021 Nov 1;101(11):pzab209. doi: 10.1093/ptj/pzab209.