PMID- 34509827 OWN - NLM STAT- MEDLINE DCOM- 20211020 LR - 20211020 IS - 1873-5800 (Electronic) IS - 0968-0160 (Linking) VI - 32 DP - 2021 Oct TI - The oxford knee score minimal clinically important difference for revision total knee arthroplasty. PG - 211-217 LID - S0968-0160(21)00204-0 [pii] LID - 10.1016/j.knee.2021.08.020 [doi] AB - BACKGROUND: Minimal clinically important difference (MCID) is crucial for interpreting meaningful improvements in patient-reported outcome measures (PROMs). No previous study has evaluated the MCID for the Oxford Knee Score (OKS) in revision total knee arthroplasty (TKA). This study aimed to propose the OKS MCID for revision TKA. METHODS: Prospectively collected data from 191 patients who underwent revision TKA at a single institution was analysed. Clinical assessment was performed preoperatively and at 2 years using OKS and Short-Form 36 Physical Component Score (SF-36 PCS). MCID was evaluated with a three-pronged methodology, using (1) anchor-based method with linear regression, (2) anchor-based method with receiver operating characteristic (ROC) and area under curve (AUC), (3) distribution-based method with standard deviation (SD). The anchors used were improvement in SF-36 PCS >/= 12, patient satisfaction, and implant survivorship following revision TKA. RESULTS: The MCID determined by anchor-based linear regression method using improvements in SF-36 PCS was 4.9 points. The MCID determined by anchor-based ROC was 10.5 points for satisfaction (AUC = 74.8%) and 13.5 points for implant survivorship (AUC = 73.7%). The MCID determined by distribution-based method of 0.5 SD was 4.7. CONCLUSION: The proposed MCID for OKS following revision TKA is 4.9 points. Patients who achieve an improvement in OKS of at least 10.5-13.5 points by 2 years are likely to be satisfied with their surgery and not require a subsequent re-revision TKA. Patients undergoing revision TKA should aim for an improvement in OKS of at least 10.5-13.5 points as a target score. CI - Copyright (c) 2021 Elsevier B.V. All rights reserved. FAU - Khow, Yong Zhi AU - Khow YZ AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. FAU - Liow, Ming Han Lincoln AU - Liow MHL AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. Electronic address: lincoln.liow.m.h@singhealth.com.sg. FAU - Goh, Graham S AU - Goh GS AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. FAU - Chen, Jerry Yongqiang AU - Chen JY AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. FAU - Lo, Ngai Nung AU - Lo NN AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. FAU - Yeo, Seng Jin AU - Yeo SJ AD - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. LA - eng PT - Journal Article DEP - 20210909 PL - Netherlands TA - Knee JT - The Knee JID - 9430798 SB - IM MH - *Arthroplasty, Replacement, Knee MH - Humans MH - Minimal Clinically Important Difference MH - *Osteoarthritis, Knee/surgery MH - Patient Reported Outcome Measures MH - Treatment Outcome OTO - NOTNLM OT - Minimal clinically important difference OT - Oxford knee score OT - Revision OT - Satisfaction OT - Survivorship OT - Total knee arthroplasty COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2021/09/13 06:00 MHDA- 2021/10/21 06:00 CRDT- 2021/09/12 20:53 PHST- 2021/04/11 00:00 [received] PHST- 2021/07/21 00:00 [revised] PHST- 2021/08/24 00:00 [accepted] PHST- 2021/09/13 06:00 [pubmed] PHST- 2021/10/21 06:00 [medline] PHST- 2021/09/12 20:53 [entrez] AID - S0968-0160(21)00204-0 [pii] AID - 10.1016/j.knee.2021.08.020 [doi] PST - ppublish SO - Knee. 2021 Oct;32:211-217. doi: 10.1016/j.knee.2021.08.020. Epub 2021 Sep 9.