PMID- 34509972
OWN - NLM
STAT- MEDLINE
DCOM- 20211203
LR  - 20211214
IS  - 1879-2219 (Electronic)
IS  - 0966-6362 (Linking)
VI  - 90
DP  - 2021 Oct
TI  - Minimal clinically important difference of modified dynamic gait index in people 
      with neurological disorders.
PG  - 210-214
LID - S0966-6362(21)00306-4 [pii]
LID - 10.1016/j.gaitpost.2021.08.024 [doi]
AB  - BACKGROUND: The minimal clinically important difference (MCID) of modified 
      Dynamic Gait Index (mDGI) has not yet been determined for People with 
      Neurological Disorders (PwND). RESEARCH QUESTION: To establish the MCID of the 
      mDGI to determine clinically meaningful improvement in balance and gait in PwND. 
      METHODS: In this longitudinal study from a randomised clinical trial, 55 
      participants both in and outpatients with neurological disorders, received 
      fifteen 40-minute rehabilitation sessions. Inpatients received daily treatments 
      over a period of three weeks while outpatients received three treatments/week 
      over a period of five weeks. An anchor-based method using percentage rating of 
      improvement in balance (Activities Balance Confidence scale, ABC) was used to 
      determine the MCID of mDGI. The MCID was defined as the minimum change in mDGI 
      total score (post - pre intervention) that was needed to perceive at least a 10 % 
      improvement on the ABC scale. A Receiver Operating Characteristic curve was used 
      to define the cut-off for the optimal MCID of the mDGI discriminating between 
      improved and not improved participants. RESULTS: The MCID of the mDGI total score 
      was 6 points and Area under the Curve was 0.64. For the mDGI time sub-scores the 
      MCID was 2 points and Area under the Curve was 0.6. SIGNIFICANCE: The MCID of 
      balance and gait improvement measured by mDGI was prudently establish at >/=7 
      points, meaning that this is the minimum improvement score PwND need to get to 
      perceive a clinically relevant change in their balance and gait confidence. These 
      reference values can be a tool incorporated into clinicians daily practice to 
      interpret mDGI change scores helping to determine whether the intervention is 
      effective; to develop clinical tailored intervention goals and to establish 
      meaningful perceived change in PwND.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Corrini, Chiara
AU  - Corrini C
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Torchio, Alessandro
AU  - Torchio A
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Anastasi, Denise
AU  - Anastasi D
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Parelli, Riccardo
AU  - Parelli R
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Meotti, Matteo
AU  - Meotti M
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Spedicato, Albino
AU  - Spedicato A
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Groppo, Elisabetta
AU  - Groppo E
AD  - U.O. Clinica Neurologica, III Ospedale San Paolo Via Antonio di Rudini 8, 20142, 
      Milano, Italy.
FAU - D'Arma, Alessia
AU  - D'Arma A
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Grosso, Cristina
AU  - Grosso C
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Montesano, Angelo
AU  - Montesano A
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
FAU - Cattaneo, Davide
AU  - Cattaneo D
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy; 
      Department of Pathophysiology and Transplantation, University of Milan 20100, 
      Milan, Italy. Electronic address: dcattaneo@dongnocchi.it.
FAU - Gervasoni, Elisa
AU  - Gervasoni E
AD  - IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20210828
PL  - England
TA  - Gait Posture
JT  - Gait & posture
JID - 9416830
SB  - IM
MH  - Disability Evaluation
MH  - Gait
MH  - Humans
MH  - Longitudinal Studies
MH  - *Minimal Clinically Important Difference
MH  - *Nervous System Diseases
OTO - NOTNLM
OT  - Dynamic balance
OT  - Minimal clinically important difference
OT  - Neurological disorders
OT  - Rehabilitation
EDAT- 2021/09/13 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/09/12 21:00
PHST- 2021/02/15 00:00 [received]
PHST- 2021/08/23 00:00 [revised]
PHST- 2021/08/27 00:00 [accepted]
PHST- 2021/09/13 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/09/12 21:00 [entrez]
AID - S0966-6362(21)00306-4 [pii]
AID - 10.1016/j.gaitpost.2021.08.024 [doi]
PST - ppublish
SO  - Gait Posture. 2021 Oct;90:210-214. doi: 10.1016/j.gaitpost.2021.08.024. Epub 2021 
      Aug 28.