PMID- 34511594
OWN - NLM
STAT- MEDLINE
DCOM- 20220107
LR  - 20220107
IS  - 2325-4416 (Electronic)
IS  - 2325-4394 (Linking)
VI  - 27
DP  - 2021 Sep 13
TI  - Size of Acute Myocardial Infarction Correlates with Earlier Time of Initiation of 
      Reperfusion Therapy with Cardiac Perfusion Scintigraphy: A National Single-Center 
      Study.
PG  - e933214
AB  - BACKGROUND The aim of this study was to determine the correlation between the 
      size of acute myocardial infarction (AMI) and the time of initiation of 
      reperfusion therapy with cardiac perfusion scintigraphy. MATERIAL AND METHODS 
      Overall, 80 patients with acute ST elevation myocardial infarction (STEMI) were 
      examined. All patients were treated with primary percutaneous coronary 
      intervention (pPCI). Data on patient and system delay expressed in minutes were 
      recorded and compared with recommended timelines. Cardiac scintigraphy was 
      performed with 99m Tc-sestamibi single-photon emission computed tomography 
      (SPECT). The median time of cardiac scintigraphy was 20 days. The correlation 
      between the size of infarction and the time of initiation of reperfusion therapy 
      was evaluated. RESULTS The mean age of patients was 60.5+/-11.5 years, and 72.5% 
      were male. The average system delay was 348 min, and the average patient delay 
      was 173 min. The mean total ischemic time was 800 min. There was a correlation 
      between time delays of reperfusion therapy and infarct size. Patients with a 
      shorter time delay to patent artery after FMC showed smaller infarct size when 
      compared to the patients with longer delay times. Multiple linear regression 
      analysis showed that FMC, being male, and smokers had statistical significance 
      when predicting infarct size. CONCLUSIONS There is a correlation between the size 
      of myocardial infarction and the time of initiation of reperfusion therapy 
      determined by perfusion myocardial scintigraphy. The study showed that there are 
      time delays in starting the treatment of AMI with pPCI when compared to the 
      recommended time, which requires an action plan in the near future to ensure 
      earlier treatment for our patients.
FAU - Citaku, Hajdin
AU  - Citaku H
AD  - Clinic for Cardiology, University Clinical Center of Kosovo, Prishtina, Kosovo.
FAU - Miftari, Rame
AU  - Miftari R
AD  - Nuclear Medicine Clinical Service, University Clinical Center of Kosovo, 
      Prishtina, Kosovo.
AD  - Department of Nuclear Medicine, Medical Faculty, University of Kosovo, Prishtina, 
      Kosovo.
FAU - Stubljar, David
AU  - Stubljar D
AD  - Department of Research and Development Slovenia, In-Medico, Metlika, Slovenia.
FAU - Krasniqi, Xhevdet
AU  - Krasniqi X
AD  - Clinic for Invasive Cardiology and Cardiac Surgery, University Clinical Center of 
      Kosovo, Prishtina, Kosovo.
AD  - Department of Internal Medicine, Medical Faculty, University of Kosovo, 
      Prishtina, Kosovo.
LA  - eng
PT  - Journal Article
DEP - 20210913
PL  - United States
TA  - Med Sci Monit Basic Res
JT  - Medical science monitor basic research
JID - 101597444
RN  - 971Z4W1S09 (Technetium Tc 99m Sestamibi)
SB  - IM
MH  - Aged
MH  - Female
MH  - Heart
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/diagnostic imaging/*therapy
MH  - *Myocardial Reperfusion
MH  - *Percutaneous Coronary Intervention
MH  - Perfusion Imaging
MH  - Technetium Tc 99m Sestamibi
MH  - Tomography, Emission-Computed, Single-Photon
EDAT- 2021/09/14 06:00
MHDA- 2022/01/08 06:00
CRDT- 2021/09/13 06:30
PHST- 2021/09/13 06:30 [entrez]
PHST- 2021/09/14 06:00 [pubmed]
PHST- 2022/01/08 06:00 [medline]
AID - 933214 [pii]
PST - epublish
SO  - Med Sci Monit Basic Res. 2021 Sep 13;27:e933214.