PMID- 34513970 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210914 IS - 2297-1769 (Print) IS - 2297-1769 (Electronic) IS - 2297-1769 (Linking) VI - 8 DP - 2021 TI - Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine. PG - 699561 LID - 10.3389/fvets.2021.699561 [doi] LID - 699561 AB - The porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen causing epidemics of porcine reproductive and respiratory syndrome (PRRS), and is present in every major swine-farming country in the world. Previous studies have demonstrated that PRRSV infection leads to a range of consequences, such as persistent infection, secondary infection, and co-infection, and is common among pigs in the field. In recent years, coinfection of PRRSV and other porcine pathogens has occurred often, making it more difficult to define and diagnose PRRSV-related diseases. The study of coinfections may be extremely suitable for the current prevention and control in the field. However, there is a limited understanding of coinfection. Therefore, in this review, we have focused on the epidemiology of PRRSV coinfection with other pathogens in swine, both in vivo and in vitro. CI - Copyright (c) 2021 Zhao, Yang, Yuan, Shen, Zhang, Shi, Zhang, Cui, Yang, Chen, Hao, Zheng, Zhang and Liu. FAU - Zhao, Dengshuai AU - Zhao D AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Yang, Bo AU - Yang B AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Yuan, Xingguo AU - Yuan X AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Shen, Chaochao AU - Shen C AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Zhang, Dajun AU - Zhang D AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Shi, Xijuan AU - Shi X AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Zhang, Ting AU - Zhang T AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Cui, Huimei AU - Cui H AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Yang, Jinke AU - Yang J AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Chen, Xuehui AU - Chen X AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Hao, Yu AU - Hao Y AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Zheng, Haixue AU - Zheng H AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Zhang, Keshan AU - Zhang K AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. FAU - Liu, Xiangtao AU - Liu X AD - State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, China. LA - eng PT - Journal Article PT - Review DEP - 20210826 PL - Switzerland TA - Front Vet Sci JT - Frontiers in veterinary science JID - 101666658 PMC - PMC8426627 OTO - NOTNLM OT - co-infection OT - pathogens OT - porcine reproductive and respiratory syndrome virus OT - porcine respiratory disease complex OT - secondary infection COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2021/09/14 06:00 MHDA- 2021/09/14 06:01 PMCR- 2021/01/01 CRDT- 2021/09/13 06:56 PHST- 2021/05/11 00:00 [received] PHST- 2021/08/02 00:00 [accepted] PHST- 2021/09/13 06:56 [entrez] PHST- 2021/09/14 06:00 [pubmed] PHST- 2021/09/14 06:01 [medline] PHST- 2021/01/01 00:00 [pmc-release] AID - 10.3389/fvets.2021.699561 [doi] PST - epublish SO - Front Vet Sci. 2021 Aug 26;8:699561. doi: 10.3389/fvets.2021.699561. eCollection 2021.