PMID- 34515258 OWN - NLM STAT- MEDLINE DCOM- 20220708 LR - 20220708 IS - 1423-0399 (Electronic) IS - 0042-1138 (Linking) VI - 106 IP - 7 DP - 2022 TI - Impact of Preoperative Stenting on the Outcome of Flexible Ureterorenoscopy for Upper Urinary Tract Urolithiasis: A Systematic Review and Meta-Analysis. PG - 679-687 LID - 10.1159/000518160 [doi] AB - PURPOSE: This study aimed to investigate the effect of preoperative stenting (POS) on the perioperative outcomes of flexible ureterorenoscopy (fURS). MATERIALS AND METHODS: A systematic review and meta-analysis was conducted based on the PRISMA statement. From the initially retrieved 609 reports, we excluded the ineligible studies at 2 stages. We only included studies that contained fURS patients with and without POS in the same report. Data of patients who underwent semirigid ureteroscope only were excluded from the analysis. The Newcastle-Ottawa Scale (NOS) system was applied for risk of bias assessment. RESULTS: A total of 20 studies including 5,852 patients were involved. 48.5% of the patients had preoperative stent. Stone-free rate was significantly higher with prestenting; odds ratio (OR) was 1.98 (95% CI: 1.51-2.58) (Z = 5.02; p = 0.00001). It also displayed tendency toward lower complications; OR was 0.74 (95% CI: 0.52-1.05) (Z = 1.67; p = 0.09). POS significantly increased the use of ureteral access sheath; OR was 1.49 (95% CI: 1.05-2.13) (Z = 2.22; p = 0.03). Risk of bias assessment showed 13 and 7 studies with low and moderate risk, respectively. CONCLUSIONS: POS clearly improves the stone-free rates after fURS. It might reduce the complications, especially ureteral injury. These findings might help solve the current debate and can be useful for urologists during patient counselling for a proper decision-making. CI - (c) 2021 S. Karger AG, Basel. FAU - Fahmy, Omar AU - Fahmy O AD - Department of Urology, Universiti Putra Malaysia, Selangor, Malaysia. FAU - Shsm, Hadi AU - Shsm H AD - Department of Urology, Royal Cornwall Hospital, Truro, United Kingdom. FAU - Lee, Cks AU - Lee C AD - Department of Urology, Universiti Putra Malaysia, Selangor, Malaysia. FAU - Khairul-Asri, Mohd Ghani AU - Khairul-Asri MG AD - Department of Urology, Universiti Putra Malaysia, Selangor, Malaysia. LA - eng PT - Meta-Analysis PT - Systematic Review DEP - 20210825 PL - Switzerland TA - Urol Int JT - Urologia internationalis JID - 0417373 SB - IM MH - Humans MH - *Kidney Calculi/surgery MH - Stents MH - *Ureter/surgery MH - Ureteroscopy MH - *Urolithiasis OTO - NOTNLM OT - Flexible ureteroscopy OT - Preoperative stenting OT - Prestenting OT - Retrograde intrarenal surgery OT - Ureterorenoscopy EDAT- 2021/09/14 06:00 MHDA- 2022/07/09 06:00 CRDT- 2021/09/13 09:28 PHST- 2021/03/20 00:00 [received] PHST- 2021/06/22 00:00 [accepted] PHST- 2021/09/14 06:00 [pubmed] PHST- 2022/07/09 06:00 [medline] PHST- 2021/09/13 09:28 [entrez] AID - 000518160 [pii] AID - 10.1159/000518160 [doi] PST - ppublish SO - Urol Int. 2022;106(7):679-687. doi: 10.1159/000518160. Epub 2021 Aug 25.