PMID- 34516579
OWN - NLM
STAT- MEDLINE
DCOM- 20211123
LR  - 20211123
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 16
IP  - 9
DP  - 2021
TI  - Size-specific dose estimates of adult, chest computed tomography examinations: 
      Comparison of Chinese and updated 2017 American College of Radiology diagnostic 
      reference levels based on the water-equivalent diameter.
PG  - e0257294
LID - 10.1371/journal.pone.0257294 [doi]
LID - e0257294
AB  - RATIONALE AND OBJECTIVES: This study aimed to compare the volume computed 
      tomography dose index (CTDIvol), dose length product (DLP), and size-specific 
      dose estimate (SSDE), with the China and updated 2017 American College of 
      Radiology (ACR) diagnostic reference levels (DRLs) in chest CT examinations of 
      adults based on the water-equivalent diameter (Dw). MATERIALS AND METHODS: All 
      chest CT examinations conducted without contrast administration from January 2020 
      to July 2020 were retrospectively included in this study. The Dw and SSDE of all 
      examinations were calculated automatically by "teamplay". The CTDIvol and DLP 
      were displayed on the DICOM-structured dose report in the console based on a 32cm 
      phantom.The differences in patient CTDIvol, DLP, and SSDE values between groups 
      were examined by the one-way ANOVA. The differences in patient CTDIvol, DLP, and 
      SSDE values between the updated 2017 ACR and the China DRLs were examined with 
      one sample t-tests. RESULTS: In total 14666 chest examinations were conducted in 
      our study. Patients were divided into four groups based on Dw:270 (1.84%) in 
      15-20 cm group, 10287 (70.14%) in the 21-25 cm group, 4097 (27.94%) in the 26-30 
      cm group, and 12 (0.08%) patients had sizes larger than 30 cm. CTDIvol, DLP, and 
      SSDE increased as a function of Dw (p<0.05). CTDIvol was smaller than SSDE among 
      groups (p<0.05). The mean CTDIvol and DLP values were lower than the 25th, 50th, 
      and 75th percentile of the China DRLs (p <0.05). The CTDIvol, DLP, and SSDE were 
      lower than the 50th and 75th percentiles of the updated 2017 ACR DRLs (p <0.05) 
      among groups. CONCLUSIONS: SSDE takes into account the influence of the scanning 
      parameters, patient size, and X-ray attenuation on the radiation dose, which can 
      give a more realistic estimate of radiation exposure dose for patients undergoing 
      CT examinations. Establishing hospital's own DRL according to CTDIvol and SSDE is 
      very important even though the radiation dose is lower than the national DRLs.
FAU - Hu, Xiaoyan
AU  - Hu X
AUID- ORCID: 0000-0002-5148-2068
AD  - Department of Radiology, Chengdu First People's Hospital, Chengdu, Sichuan 
      Province, China.
FAU - Gou, Jie
AU  - Gou J
AD  - Department of Radiology, Chengdu First People's Hospital, Chengdu, Sichuan 
      Province, China.
FAU - Lin, Wei
AU  - Lin W
AD  - Department of Radiology, Chengdu First People's Hospital, Chengdu, Sichuan 
      Province, China.
FAU - Zou, Chunhua
AU  - Zou C
AD  - Department of Radiology, Chengdu First People's Hospital, Chengdu, Sichuan 
      Province, China.
FAU - Li, Wenbo
AU  - Li W
AUID- ORCID: 0000-0003-2593-6131
AD  - Department of Radiology, Chengdu First People's Hospital, Chengdu, Sichuan 
      Province, China.
LA  - eng
PT  - Journal Article
DEP - 20210913
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - China
MH  - Diagnostic Reference Levels
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radiation Dosage
MH  - Reference Values
MH  - Retrospective Studies
MH  - Tomography, X-Ray Computed/*methods/standards
PMC - PMC8437305
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/09/14 06:00
MHDA- 2021/11/24 06:00
PMCR- 2021/09/13
CRDT- 2021/09/13 17:28
PHST- 2021/03/08 00:00 [received]
PHST- 2021/08/28 00:00 [accepted]
PHST- 2021/09/13 17:28 [entrez]
PHST- 2021/09/14 06:00 [pubmed]
PHST- 2021/11/24 06:00 [medline]
PHST- 2021/09/13 00:00 [pmc-release]
AID - PONE-D-21-05170 [pii]
AID - 10.1371/journal.pone.0257294 [doi]
PST - epublish
SO  - PLoS One. 2021 Sep 13;16(9):e0257294. doi: 10.1371/journal.pone.0257294. 
      eCollection 2021.