PMID- 34517976
OWN - NLM
STAT- MEDLINE
DCOM- 20211210
LR  - 20211214
IS  - 1768-3181 (Electronic)
IS  - 0003-3928 (Linking)
VI  - 70
IP  - 4
DP  - 2021 Oct
TI  - [Study of the factors contributing to poor quality of life in chronic heart 
      failure with reduced ejection fraction].
PG  - 231-236
LID - S0003-3928(21)00087-1 [pii]
LID - 10.1016/j.ancard.2021.07.004 [doi]
AB  - BACKGROUND: The increasing prevalence and poor prognosis associated with chronic 
      heart failure (CHF) have made the improvement of quality of life (QoL) one of the 
      main goals in the treatment of CHF patients. Since little is known about the QoL 
      in Tunisian patients with heart failure (HF), the current study was performed to 
      assess QoL in a sample of Tunisian patients hospitalized with HF and to identify 
      factors related to QoL. METHODS: In this prospective study, we evaluated patients 
      with CHF attending the cardiology department of Habib Thameur University Hospital 
      in a four-month period. Echocardiography was performed and patients with left 
      ventricular ejection fraction of 45% or less were selected. QoL assessment was 
      performed with a disease-specific instrument: the Minnesota Living with Heart 
      Failure Questionnaire (MLHFQ) in a sample of 100 selected patients. Relationships 
      between health-related QoL and the studied variables were examined with bivariate 
      correlations and binary logistic regression analysis. RESULTS: In the total 
      sample (n = 100), mean age was 62.7 years. The majority were male (77%), married 
      (76%), with a mean of 2.5 comorbidities, and in a New York Heart Association 
      (NYHA) functional class III to IV (61%). Mean LVEF was 36%. Half of the patients 
      had poor QoL on the total MLHFQ scale (median = 41.5) as well as on its physical 
      (median = 17.5) and emotional (median = 11.25) domains. In univariate analysis, 
      the following variables were related to poor QoL with p < 0.005: not being 
      employed, suffering from hypertension, renal failure, anemia, being under a 
      low-salt diet, having no regular physical activity, having the physical symptoms 
      of HF, higher NYHA class and longer QRS duration. In multiple regression 
      analysis, the main independent predictors of poor QoL on the total scale were 
      higher NYHA functional class and renal dysfunction,. The data provided no 
      evidence of an association between LVEF and QoL. CONCLUSION: This study has found 
      that higher NHYA functional class and chronic kidney disease are risk factors for 
      impaired QoL, independently of disease severity among patients with heart 
      failure.
CI  - Copyright (c) 2021 Elsevier Masson SAS. All rights reserved.
FAU - Ihsen, Zairi
AU  - Ihsen Z
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040. 
      Electronic address: zairiihsen@yahoo.fr.
FAU - Khadija, Mzoughi
AU  - Khadija M
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040.
FAU - Marwa, Chouaieb
AU  - Marwa C
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040.
FAU - Imtinen, Ben Mrad
AU  - Imtinen BM
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040.
FAU - Fethia, Ben Moussa
AU  - Fethia BM
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040.
FAU - Sofien, Kamoun
AU  - Sofien K
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040. 
      Electronic address: kamounsofien@yahoo.fr.
FAU - Sondos, Kraiem
AU  - Sondos K
AD  - Service de cardiologie Hopital Habib Thameur, 03 Rue Salman el Fersi Rades 2040.
LA  - fre
PT  - Journal Article
TT  - Etude des facteurs de mauvaise qualite de vie de l'insuffisant cardiaque 
      chronique a fraction d'ejection alteree.
DEP - 20210910
PL  - France
TA  - Ann Cardiol Angeiol (Paris)
JT  - Annales de cardiologie et d'angeiologie
JID - 0142167
SB  - IM
MH  - Female
MH  - *Heart Failure
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Stroke Volume
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Heart failure
OT  - Insuffisance cardiaque
OT  - Quality of life
OT  - Qualite de vie
OT  - Questionnaire
EDAT- 2021/09/15 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/09/14 05:47
PHST- 2020/08/18 00:00 [received]
PHST- 2021/07/01 00:00 [accepted]
PHST- 2021/09/15 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/09/14 05:47 [entrez]
AID - S0003-3928(21)00087-1 [pii]
AID - 10.1016/j.ancard.2021.07.004 [doi]
PST - ppublish
SO  - Ann Cardiol Angeiol (Paris). 2021 Oct;70(4):231-236. doi: 
      10.1016/j.ancard.2021.07.004. Epub 2021 Sep 10.