PMID- 34521485
OWN - NLM
STAT- MEDLINE
DCOM- 20220713
LR  - 20220713
IS  - 1467-1107 (Electronic)
IS  - 1047-9511 (Linking)
VI  - 32
IP  - 7
DP  - 2022 Jul
TI  - Contemporary outcomes of aortic arch hypoplasia and coarctation repair in a 
      tertiary paediatric cardiac surgery centre.
PG  - 1098-1103
LID - 10.1017/S1047951121003747 [doi]
AB  - OBJECTIVES: There are several studies reporting the outcomes of hypoplastic 
      aortic arch and aortic coarctation repair with combination of techniques. 
      However, only few studies reported of aortic arch and coarctation repair using a 
      homograft patch through sternotomy and circulatory arrest with retrograde 
      cerebral perfusion. We report our experience and outcomes of this cohort of 
      neonates and infants. METHODS: We performed retrospective data collection for all 
      neonates and infants who underwent aortic arch reconstruction between 2015 and 
      2020 at our institute. Data are presented as median and inter-quartile range 
      (IQR). RESULTS: The cohort included 76 patients: 49 were males (64.5%). Median 
      age at operation was 16 days (IQR 9-43.25 days). Median weight was 3.5 kg (IQR 
      3.10-4 kg). There was no 30 days mortality. Three patients died in hospital after 
      30 days (3.95%), neurological adverse events occurred in only one patient (1.32%) 
      and recurrent laryngeal nerve injury was noted in four patients (5.26%). Only 
      three patients required the support of extracorporeal membrane oxygenation (ECMO) 
      with a median ECMO run of 4 days. Median follow-up was 35 months (IQR 18.9-46.4 
      months); 5 years survival was 93.42% (n = 71). The rate of re-intervention on the 
      aortic arch was 9.21% (n = 7). CONCLUSION: Our experience shows excellent 
      outcomes in repairing aortic arch hypoplasia with homograft patch under moderate 
      to deep hypothermia with low in-hospital and 5 years mortality rates.
FAU - Ashry, Amr
AU  - Ashry A
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
AD  - Department of Cardiothoracic Surgery, Assiut University Hospital, Faculty of 
      Medicine, Assiut University, Assiut, Egypt.
FAU - Harky, Amer
AU  - Harky A
AUID- ORCID: 0000-0001-5507-5841
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
AD  - School of Medicine, Faculty of Health and Life Sciences, University of Liverpool, 
      Liverpool, UK.
AD  - Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, 
      Liverpool, UK.
AD  - Liverpool Centre for Cardiovascular Science, University of Liverpool and 
      Liverpool Heart and Chest Hospital, Liverpool, UK.
FAU - Tarmahomed, Abdulla
AU  - Tarmahomed A
AD  - Department of Paediatric Cardiology, Alder Hey Children Hospital, Liverpool, UK.
FAU - Ugwu, Christopher
AU  - Ugwu C
AD  - Department of Paediatric Cardiology, Alder Hey Children Hospital, Liverpool, UK.
FAU - Mohammed, Heba M
AU  - Mohammed HM
AD  - Department of Public Health and Community Medicine, Faculty of Medicine, Assiut 
      University, Assiut, Egypt.
FAU - Kutty, Ramesh
AU  - Kutty R
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
FAU - Lotto, Attilio
AU  - Lotto A
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
AD  - Liverpool Centre for Cardiovascular Science, University of Liverpool and 
      Liverpool Heart and Chest Hospital, Liverpool, UK.
AD  - Faculty of Health, Liverpool John Moores University, Liverpool, UK.
FAU - Guerrero, Rafael
AU  - Guerrero R
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
FAU - Dhannapuneni, Ramana
AU  - Dhannapuneni R
AD  - Department of Paediatric Cardiac Surgery, Alder Hey Children Hospital, Liverpool, 
      UK.
LA  - eng
PT  - Journal Article
DEP - 20210915
PL  - England
TA  - Cardiol Young
JT  - Cardiology in the young
JID - 9200019
SB  - IM
MH  - Aorta, Thoracic/abnormalities/surgery
MH  - *Aortic Coarctation/surgery
MH  - *Cardiac Surgical Procedures/methods
MH  - Child
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Vascular Surgical Procedures/methods
OTO - NOTNLM
OT  - Aortic arch hypoplasia
OT  - coarctation
OT  - homograft
OT  - selective cerebral perfusion
EDAT- 2021/09/16 06:00
MHDA- 2022/07/14 06:00
CRDT- 2021/09/15 05:49
PHST- 2021/09/16 06:00 [pubmed]
PHST- 2022/07/14 06:00 [medline]
PHST- 2021/09/15 05:49 [entrez]
AID - S1047951121003747 [pii]
AID - 10.1017/S1047951121003747 [doi]
PST - ppublish
SO  - Cardiol Young. 2022 Jul;32(7):1098-1103. doi: 10.1017/S1047951121003747. Epub 
      2021 Sep 15.