PMID- 34522562 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220429 IS - 2168-8184 (Print) IS - 2168-8184 (Linking) VI - 13 IP - 9 DP - 2021 Sep TI - Light Chain Glomerulopathy Causing Kidney Failure in Renal Cell Carcinoma. PG - e17850 LID - 10.7759/cureus.17850 [doi] AB - Light chain deposition disease (LCDD) is a rare cause of kidney failure. It is associated with multiple myeloma and is diagnosed by the evaluation of serum and urine free light chains. Patients who are diagnosed with this disease often develop rapidly progressive renal failure. To our knowledge, it does not have any association with other malignancies aside from multiple myeloma. We present a case that highlights a novel association between renal cell carcinoma and light chain-mediated renal disease. Our patient was admitted due to acute renal failure and underwent a comprehensive diagnostic evaluation with an eventual diagnosis of light chain glomerulopathy in the setting of metastatic renal cell carcinoma. CI - Copyright (c) 2021, Farzam et al. FAU - Farzam, Khashayar AU - Farzam K AD - Family Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA. FAU - Zarei, Keyan AU - Zarei K AD - Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA. LA - eng GR - T32 GM007337/GM/NIGMS NIH HHS/United States GR - T32 GM139776/GM/NIGMS NIH HHS/United States PT - Case Reports PT - Retracted Publication DEP - 20210909 PL - United States TA - Cureus JT - Cureus JID - 101596737 RIN - Cureus. 2021 Dec 6;13(12):r38. PMID: 34926100 OTO - NOTNLM OT - light cast chain nephropathy OT - light chain deposition disease OT - multiple myeloma OT - renal cell caricnoma OT - systemic capillary leak syndrome COIS- The authors have declared that no competing interests exist. EDAT- 2021/09/16 06:00 MHDA- 2021/09/16 06:01 CRDT- 2021/09/15 07:17 PHST- 2021/09/09 00:00 [accepted] PHST- 2021/09/15 07:17 [entrez] PHST- 2021/09/16 06:00 [pubmed] PHST- 2021/09/16 06:01 [medline] AID - 10.7759/cureus.17850 [doi] PST - epublish SO - Cureus. 2021 Sep 9;13(9):e17850. doi: 10.7759/cureus.17850. eCollection 2021 Sep.