PMID- 34525958
OWN - NLM
STAT- MEDLINE
DCOM- 20220118
LR  - 20220118
IS  - 1471-2261 (Electronic)
IS  - 1471-2261 (Linking)
VI  - 21
IP  - 1
DP  - 2021 Sep 15
TI  - Predictive value of CHADS(2) and CHA(2)DS(2)-VASc scores for coronary artery 
      lesions and in-hospital prognosis of patients with acute ST-segment elevation 
      myocardial infarction.
PG  - 439
LID - 10.1186/s12872-021-02257-2 [doi]
LID - 439
AB  - OBJECTIVE: To evaluate the predictive value of CHADS(2) and CHA(2)DS(2)-VASc 
      scores for coronary artery lesions and in-hospital prognosis of patients with 
      acute ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 524 
      patients who were diagnosed with STEMI from January 2016 to August 2017 were 
      retrospectively reviewed. The correlation between CHADS(2) and CHA(2)DS(2)-VASc 
      scores with the patients' clinical data, number of coronary lesions, Gensini 
      scores, the target vessel and hospitalization time and in-hospital adverse events 
      (AEs) was analyzed. RESULTS: The number of coronary lesions in STEMI patients was 
      mainly single and double lesions. The CHADS(2) and CHA(2)DS(2)-VASc scores were 
      not meaningful for predicting the number of coronary lesions. However, for left 
      main coronary artery lesion, CHADS(2) score was significantly increased when the 
      number increased (P < 0.05), but CHA(2)DS(2)-VASc score showed no statistical 
      difference (P > 0.05). The incidence of target lesions in STMEI patients was 
      mainly left anterior descending coronary artery (LAD) and right coronary artery 
      (RCA). The two scores were not meaningful for predicting target lesions 
      (P > 0.05). For the severity of coronary lesions, there was positive correlation 
      between CHADS(2) score with Gensini score (P < 0.05), but no exact correlation 
      between CHA(2)DS(2)-VASc score and Gensini score (P > 0.05). The stratifications 
      of CHADS(2) score and CHA(2)DS(2)-VASc score were significantly associated with 
      hospitalization time and adverse events during hospitalization (P < 0.05). The 
      high score group had longer hospitalization time and more AEs during 
      hospitalization than the low score group and the middle group statistically 
      (P < 0.05). CONCLUSION: CHADS(2) score had a certain value to predict the 
      severity of coronary lesion and the presence of left main coronary artery in 
      STEMI. The CHA(2)DS(2)-VASc score had no predictive ability to do it. There was 
      no significant value in predicting the number of coronary lesions and the 
      location of the target lesions in STEMI patients. However, both scores had the 
      predictive ability for patient hospitalization and AEs during hospitalization.
CI  - (c) 2021. The Author(s).
FAU - Li, Xiaoli
AU  - Li X
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University; 
      Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang 
      Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, 
      Beijing, 100020, China.
FAU - Zeng, Zhen
AU  - Zeng Z
AD  - Geriatric Department, Chui Yang Liu Hospital, Tsinghua University, Beijing, 
      100022, China.
FAU - Yang, Xinchun
AU  - Yang X
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University; 
      Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang 
      Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, 
      Beijing, 100020, China.
FAU - Wang, Hongjiang
AU  - Wang H
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University; 
      Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang 
      Hospital, Capital Medical University, No.8 Gongti South Road, Chaoyang District, 
      Beijing, 100020, China. yangxinchuncyyy1@163.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210915
PL  - England
TA  - BMC Cardiovasc Disord
JT  - BMC cardiovascular disorders
JID - 100968539
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Coronary Artery Disease/*diagnosis/therapy
MH  - *Decision Support Techniques
MH  - Female
MH  - *Hospitalization
MH  - Humans
MH  - Length of Stay
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*diagnosis/therapy
MH  - Severity of Illness Index
MH  - Time Factors
PMC - PMC8442268
OTO - NOTNLM
OT  - Acute ST-segment elevation myocardial infarction
OT  - Adverse events during hospitalization
OT  - CHA2DS2-VASc score
OT  - CHADS2 score
OT  - Gensini score
COIS- The authors declare that they have no competing interests.
EDAT- 2021/09/17 06:00
MHDA- 2022/01/19 06:00
PMCR- 2021/09/15
CRDT- 2021/09/16 05:41
PHST- 2021/04/20 00:00 [received]
PHST- 2021/09/08 00:00 [accepted]
PHST- 2021/09/16 05:41 [entrez]
PHST- 2021/09/17 06:00 [pubmed]
PHST- 2022/01/19 06:00 [medline]
PHST- 2021/09/15 00:00 [pmc-release]
AID - 10.1186/s12872-021-02257-2 [pii]
AID - 2257 [pii]
AID - 10.1186/s12872-021-02257-2 [doi]
PST - epublish
SO  - BMC Cardiovasc Disord. 2021 Sep 15;21(1):439. doi: 10.1186/s12872-021-02257-2.