PMID- 34535244 OWN - NLM STAT- MEDLINE DCOM- 20211125 LR - 20211125 IS - 1532-6497 (Electronic) IS - 1067-991X (Linking) VI - 40 IP - 5 DP - 2021 Sep-Oct TI - Safety Matters: A Meta-analysis of Interhospital Transport Adverse Events in Critically Ill Patients. PG - 350-358 LID - S1067-991X(21)00088-2 [pii] LID - 10.1016/j.amj.2021.04.008 [doi] AB - OBJECTIVE: Interhospital transport (IHT) is common among critically ill patients. Our meta-analysis investigated the prevalence and possible factors associated with adverse events (AEs) during IHT. METHODS: Searching PubMed, Embase, and Scopus databases until February 12, 2021, we included studies that a priori defined AEs for adult medical patients. We excluded case reports, non-full-text, and non-English language studies. We performed a random effects meta-analysis and moderator analyses. RESULTS: We identified 554 studies and included 19 studies (14,969 patients) in our final analysis. The mean patients' (standard deviation) age was 60 (13.7). The pooled medical AEs for IHT was 1,059 (11%, 95% confidence interval, 7.5%-16%). The most common AE (n, %) was hypotension (424, 2.8%). Moderator analyses and meta-regressions suggested that conditions (P < .001) such as respiratory failure from coronavirus infection (88%), stroke (19%), and the need for extracorporeal membrane oxygenation (40%) were associated with higher AE prevalence. Transport by nurses (31%) and physicians (11%) was associated with a higher AE prevalence, whereas transport type did not influence AE prevalence. CONCLUSION: Our study suggests the prevalence of AEs of critically ill patients during IHT is low and likely due to patients' disease severity. Further studies should focus on interventions to mitigate AEs to improve patients' outcomes. CI - Copyright (c) 2021 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved. FAU - Jeyaraju, Maniraj AU - Jeyaraju M AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Andhavarapu, Sanketh AU - Andhavarapu S AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Palmer, Jamie AU - Palmer J AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Bzhilyanskaya, Vera AU - Bzhilyanskaya V AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Friedman, Eric AU - Friedman E AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Lurie, Tucker AU - Lurie T AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Patel, Priya AU - Patel P AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Raffman, Alison AU - Raffman A AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Wang, Jennifer AU - Wang J AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD. FAU - Tran, Quincy K AU - Tran QK AD - Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD; Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD; Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD. Electronic address: qtran@som.umaryland.edu. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review DEP - 20210524 PL - United States TA - Air Med J JT - Air medical journal JID - 9312325 MH - Adult MH - Critical Illness MH - *Extracorporeal Membrane Oxygenation MH - Humans MH - *Respiratory Insufficiency EDAT- 2021/09/19 06:00 MHDA- 2021/11/26 06:00 CRDT- 2021/09/18 05:31 PHST- 2021/03/12 00:00 [received] PHST- 2021/04/16 00:00 [accepted] PHST- 2021/09/18 05:31 [entrez] PHST- 2021/09/19 06:00 [pubmed] PHST- 2021/11/26 06:00 [medline] AID - S1067-991X(21)00088-2 [pii] AID - 10.1016/j.amj.2021.04.008 [doi] PST - ppublish SO - Air Med J. 2021 Sep-Oct;40(5):350-358. doi: 10.1016/j.amj.2021.04.008. Epub 2021 May 24.