PMID- 34538762
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221029
IS  - 2531-1387 (Electronic)
IS  - 2531-1379 (Print)
IS  - 2531-1379 (Linking)
VI  - 44
IP  - 4
DP  - 2022 Oct-Dec
TI  - Comparative analysis of hematological parameters of first-time and repeat blood 
      donors: Experience of a blood bank in southern Nigeria.
PG  - 512-518
LID - S2531-1379(21)00124-3 [pii]
LID - 10.1016/j.htct.2021.06.013 [doi]
AB  - INTRODUCTION: The safety of a blood transfusion practice is anchored on safe 
      blood from a healthy donor, while further protecting the donor from future harm. 
      This study aimed to evaluate the hematological parameters of blood donors in view 
      of their donor category to aid in assessing the safety threshold in terms of 
      donation frequency. METHODS: This study made use of the descriptive 
      cross-sectional design. The blood donors were bled and their samples analyzed 
      using a hematology autoanalyzer. RESULTS: A total of 178 male blood donors were 
      recruited. Most of the donors were aged 18 to 39 years and were mostly students. 
      A greater part of them were repeat donors who had donated blood more than four 
      times. First- and second-time donors constituted the majority of the voluntary 
      donors. While the total red cell count was significantly lower in repeat 
      third-time donors, the hemoglobin and hematocrit of the first-time donors were 
      significantly higher than those of the repeat fourth-time donors. The mean 
      corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) 
      of the first-time donors were significantly higher than those of the repeat 
      fifth-time donors. The red cell distribution width (RDW) and mean platelet volume 
      (MPV) were significantly lower in the first-time donors from those of the sixth- 
      and seventh-time donors, respectively. Most of the fifth-time donors have 
      subclinical anemia. There was more subclinical anemia in commercial donors than 
      in voluntary donors. CONCLUSION: Repeat donors more than fifth-time donors are at 
      risk of donation-induced iron deficiency anemia.
CI  - Copyright (c) 2021 Associacao Brasileira de Hematologia, Hemoterapia e Terapia 
      Celular. Published by Elsevier Espana, S.L.U. All rights reserved.
FAU - Ogar, Christopher Ogar
AU  - Ogar CO
AD  - University of Calabar, Calabar, Nigeria.
FAU - Okpokam, Dorathy Chioma
AU  - Okpokam DC
AD  - University of Calabar, Calabar, Nigeria.
FAU - Okoroiwu, Henshaw Uchechi
AU  - Okoroiwu HU
AD  - University of Calabar, Calabar, Nigeria. Electronic address: 
      okoroiwuhenshaw@gmail.com.
FAU - Okafor, Ifeyinwa Maryann
AU  - Okafor IM
AD  - University of Calabar, Calabar, Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20210911
PL  - Brazil
TA  - Hematol Transfus Cell Ther
JT  - Hematology, transfusion and cell therapy
JID - 101725732
PMC - PMC9605908
OTO - NOTNLM
OT  - Anemia in donors
OT  - Blood donors
OT  - Hematological parameters
COIS- Conflicts of interest The authors declare none.
EDAT- 2021/09/21 06:00
MHDA- 2021/09/21 06:01
PMCR- 2021/09/11
CRDT- 2021/09/20 05:48
PHST- 2021/02/16 00:00 [received]
PHST- 2021/05/18 00:00 [revised]
PHST- 2021/06/25 00:00 [accepted]
PHST- 2021/09/21 06:00 [pubmed]
PHST- 2021/09/21 06:01 [medline]
PHST- 2021/09/20 05:48 [entrez]
PHST- 2021/09/11 00:00 [pmc-release]
AID - S2531-1379(21)00124-3 [pii]
AID - 10.1016/j.htct.2021.06.013 [doi]
PST - ppublish
SO  - Hematol Transfus Cell Ther. 2022 Oct-Dec;44(4):512-518. doi: 
      10.1016/j.htct.2021.06.013. Epub 2021 Sep 11.