PMID- 34543884
OWN - NLM
STAT- MEDLINE
DCOM- 20211124
LR  - 20211124
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1656
DP  - 2021 Oct 25
TI  - Capillary coated with three-dimensional covalent organic frameworks for 
      separation of fluoroquinolones by open-tubular capillary electrochromatography.
PG  - 462549
LID - S0021-9673(21)00673-7 [pii]
LID - 10.1016/j.chroma.2021.462549 [doi]
AB  - The Schiff-base reaction of 1,3,5-triformylphloroglucinol (Tp) and 
      tetra(4-aminophenyl)methane (TAM) was performed for the synthesis of a 
      three-dimensional covalent organic framework named 3D TpTAM, which was obtained 
      by an ultrasound-assisted method for the first time. The morphology and structure 
      of the synthesized TpTAM were characterized through various methods. Then, 
      TpTAM-coated capillary columns were subsequently prepared by a covalent bonding 
      method within a short time and applied for the separation of fluoroquinolones by 
      capillary electrochromatography (CEC) with good resolution and reproducibility. 
      The intraday relative standard deviations (RSDs) of the retention time and peak 
      areas were 0.88%-0.95% and 2.27%-3.81%, respectively. The interday RSDs of 
      retention time and peak areas were 0.71%-0.89% and 0.88%-3.60%, respectively. The 
      column-to-column RSDs of retention time and peak areas were less than 1.90% and 
      13.56%, respectively. The interbatch RSDs of retention time and peak areas were 
      less than 3.48% and 3.89%, respectively. The TpTAM-coated capillary columns could 
      be used for no less than 100 runs with no observable changes in the separation 
      efficiency. The separation mechanism was also studied, which indicated that pi-pi 
      stacking effects, hydrophobic interactions and hydrogen bonding were the main 
      factors. The results revealed that 3D TpTAM should have superior potential as the 
      stationary phase in CEC for chromatographic separation.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Zong, Rui
AU  - Zong R
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China.
FAU - Wang, Xuan
AU  - Wang X
AD  - China Institute of Veterinary Drug Control, Beijing 100081, PR China.
FAU - Yin, Han
AU  - Yin H
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China.
FAU - Li, Zijian
AU  - Li Z
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China.
FAU - Huang, Chuanlin
AU  - Huang C
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China.
FAU - Xiang, Yuhong
AU  - Xiang Y
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China. 
      Electronic address: xiangyh@cnu.edu.cn.
FAU - Ye, Nengsheng
AU  - Ye N
AD  - Department of Chemistry, Capital Normal University, Beijing 100048, PR China. 
      Electronic address: yensh@cnu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20210910
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Fluoroquinolones)
RN  - 0 (Metal-Organic Frameworks)
RN  - OP0UW79H66 (Methane)
SB  - IM
MH  - *Capillary Electrochromatography
MH  - Fluoroquinolones
MH  - *Metal-Organic Frameworks
MH  - Methane
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - Capillary electrochromatography
OT  - Fluoroquinolones
OT  - Open-tubular capillary
OT  - Three-dimensional covalent organic frameworks
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2021/09/21 06:00
MHDA- 2021/11/25 06:00
CRDT- 2021/09/20 20:23
PHST- 2021/05/29 00:00 [received]
PHST- 2021/09/02 00:00 [revised]
PHST- 2021/09/05 00:00 [accepted]
PHST- 2021/09/21 06:00 [pubmed]
PHST- 2021/11/25 06:00 [medline]
PHST- 2021/09/20 20:23 [entrez]
AID - S0021-9673(21)00673-7 [pii]
AID - 10.1016/j.chroma.2021.462549 [doi]
PST - ppublish
SO  - J Chromatogr A. 2021 Oct 25;1656:462549. doi: 10.1016/j.chroma.2021.462549. Epub 
      2021 Sep 10.