PMID- 34544989
OWN - NLM
STAT- MEDLINE
DCOM- 20211011
LR  - 20211011
IS  - 1349-3299 (Electronic)
IS  - 1349-2365 (Linking)
VI  - 62
IP  - 5
DP  - 2021 Sep 30
TI  - Fatal Pulmonary Hemorrhagic Infarction Caused by Pulmonary Vein Thrombotic 
      Occlusion During Venoarterial Extracorporeal Membrane Oxygenation.
PG  - 1182-1185
LID - 10.1536/ihj.21-226 [doi]
AB  - A 20-year-old man with arrhythmogenic right ventricular cardiomyopathy (ARVC) was 
      resuscitated from ventricular fibrillation. He was transferred to our hospital 
      because of progressive multiorgan dysfunction despite mechanical circulatory 
      support with peripheral venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) and intra-aortic balloon pump (IABP). At admission to our hospital, 
      chest X-ray showed bilateral complete lung opacification, and echocardiography 
      revealed a massive thrombus occupying the left atrium (LA) and left ventricle 
      (LV). Conversion to central ECMO with transapical LV venting and thrombectomy 
      were performed. The huge LA thrombus occluded all pulmonary veins (PVs). Despite 
      the surgery and intensive care, complete lung opacity remained, and he died of 
      multiorgan failure associated with sepsis. Autopsy demonstrated bilateral 
      pulmonary multiple red infarctions, and histopathology showed alveolar wall 
      necrosis with extensive hemorrhage, confirming a diagnosis of pulmonary 
      hemorrhagic infarction. Extensive pulmonary infarction was attributable to PV 
      occlusion due to massive LA thrombus. PV thrombosis should be considered when 
      refractory lung opacities are encountered during VA-ECMO and necessitates early 
      intervention.
FAU - Masaki, Kohei
AU  - Masaki K
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Hashimoto, Toru
AU  - Hashimoto T
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
AD  - Department of Advanced Cardiopulmonary Failure, Faculty of Medical Sciences, 
      Kyushu University.
FAU - Katsuki, Masato
AU  - Katsuki M
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Ohtani, Kisho
AU  - Ohtani K
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Higo, Taiki
AU  - Higo T
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Ushijima, Tomoki
AU  - Ushijima T
AD  - Department of Cardiovascular Surgery, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Tanoue, Yoshihisa
AU  - Tanoue Y
AD  - Department of Advanced Cardiopulmonary Failure, Faculty of Medical Sciences, 
      Kyushu University.
AD  - Department of Cardiovascular Surgery, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Shiose, Akira
AU  - Shiose A
AD  - Department of Cardiovascular Surgery, Faculty of Medical Sciences, Kyushu 
      University.
FAU - Tsutsui, Hiroyuki
AU  - Tsutsui H
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu 
      University.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20210917
PL  - Japan
TA  - Int Heart J
JT  - International heart journal
JID - 101244240
SB  - IM
MH  - Arrhythmogenic Right Ventricular Dysplasia/*complications
MH  - Autopsy/methods
MH  - Echocardiography/methods
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Fatal Outcome
MH  - Heart Atria/diagnostic imaging/pathology
MH  - Heart Ventricles/diagnostic imaging/pathology
MH  - Hemorrhage/complications/diagnosis
MH  - Humans
MH  - Intra-Aortic Balloon Pumping/methods
MH  - Male
MH  - Multiple Organ Failure/*complications
MH  - Pulmonary Infarction/diagnosis
MH  - Pulmonary Veins/diagnostic imaging/pathology
MH  - Pulmonary Veno-Occlusive Disease/complications/diagnosis
MH  - Resuscitation/methods
MH  - Sepsis/complications
MH  - Thrombectomy/methods
MH  - Thrombosis/*diagnosis/pathology/surgery
MH  - Ventricular Fibrillation/*etiology/therapy
MH  - Young Adult
OTO - NOTNLM
OT  - Arrhythmogenic right ventricular cardiomyopathy
OT  - Intracardiac thrombosis
OT  - Left ventricular venting
OT  - Pulmonary vein thrombosis
EDAT- 2021/09/22 06:00
MHDA- 2021/10/12 06:00
CRDT- 2021/09/21 05:52
PHST- 2021/09/22 06:00 [pubmed]
PHST- 2021/10/12 06:00 [medline]
PHST- 2021/09/21 05:52 [entrez]
AID - 10.1536/ihj.21-226 [doi]
PST - ppublish
SO  - Int Heart J. 2021 Sep 30;62(5):1182-1185. doi: 10.1536/ihj.21-226. Epub 2021 Sep 
      17.