PMID- 34547405
OWN - NLM
STAT- MEDLINE
DCOM- 20211213
LR  - 20220531
IS  - 1873-6815 (Electronic)
IS  - 0531-5565 (Linking)
VI  - 155
DP  - 2021 Nov
TI  - Regular physical activity reduces the effects of inflammaging in diabetic and 
      hypertensive men.
PG  - 111558
LID - S0531-5565(21)00340-5 [pii]
LID - 10.1016/j.exger.2021.111558 [doi]
AB  - The aim of this study was to assess the influence of physical activity in 
      inflammatory, biochemical and endocrine parameters of middle-aged and elderly men 
      with Systemic Arterial Hypertension (SAH) and Type 2 Diabetes Mellitus (T2DM). 
      The assessment was comprised by 77 male volunteers aged between 45 and 59 years 
      old (middle-aged men) or 60 to 86 years old (elderly men), diagnosed with SAH and 
      T2DM, assisted by Family Health Units in Vitoria da Conquista, Bahia, Brazil. 
      According to age and lifestyle (sedentary or practicing physical activity), these 
      men were classified as middle-aged sedentary men, middle-aged physically active 
      men, elderly sedentary men, or elderly physically active men. It was noticed that 
      active elderly people with SAH and T2DM had a better inflammatory balance than 
      sedentary middle-aged men, through the evaluation of the relationship between the 
      cytokines IL-10/TNF-alpha, IL-10/IL-17A and IL-10/IFN-gamma. Moreover, in the extended 
      correlation analysis, a greater global balance was observed among anthropometric, 
      blood pressure, biochemical and cytokine parameters. Physical activity 
      beneficially modulates aging-related disease risk factors even in elderly 
      individuals.
CI  - Copyright (c) 2021 Elsevier Inc. All rights reserved.
FAU - Ribeiro, Israel S
AU  - Ribeiro IS
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil; Paulo Freire Campus - Federal 
      University of Southern Bahia, 250 Joana Angelica Square, Sao Jose, 45.988-058 
      Teixeira de Freitas, Bahia, Brazil.
FAU - Pereira, Italo S
AU  - Pereira IS
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil.
FAU - Galantini, Maria P L
AU  - Galantini MPL
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil.
FAU - Santos, Denisar P
AU  - Santos DP
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil; FG Universitary Center - UniFG, 
      459 Barao do Rio Branco Avenue, Zip code: 46430-000 Guanambi, Bahia, Brazil.
FAU - Teles, Mauro F
AU  - Teles MF
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil.
FAU - Muniz, Igor P R
AU  - Muniz IPR
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil.
FAU - Santos, Gilvaneia S
AU  - Santos GS
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil.
FAU - Silva, Robson A A
AU  - Silva RAA
AD  - Multidisciplinary Institute of Health, Anisio Teixeira Campus - Federal 
      University of Bahia, 58 Hormindo Barros Street - 17 Block - 58 Lot, Candeias, 
      45.029-094 Vitoria da Conquista, Bahia, Brazil. Electronic address: 
      ramaro@ufba.br.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210920
PL  - England
TA  - Exp Gerontol
JT  - Experimental gerontology
JID - 0047061
RN  - 0 (Cytokines)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Aging
MH  - Cytokines
MH  - *Diabetes Mellitus, Type 2
MH  - *Exercise
MH  - Humans
MH  - *Hypertension
MH  - Inflammation/*prevention & control
MH  - Life Style
MH  - Male
MH  - Middle Aged
OTO - NOTNLM
OT  - Aging
OT  - Men
OT  - Physical activity
OT  - Systemic arterial hypertension
OT  - Type 2 diabetes mellitus
EDAT- 2021/09/22 06:00
MHDA- 2021/12/15 06:00
CRDT- 2021/09/21 20:15
PHST- 2021/06/20 00:00 [received]
PHST- 2021/09/13 00:00 [revised]
PHST- 2021/09/15 00:00 [accepted]
PHST- 2021/09/22 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/09/21 20:15 [entrez]
AID - S0531-5565(21)00340-5 [pii]
AID - 10.1016/j.exger.2021.111558 [doi]
PST - ppublish
SO  - Exp Gerontol. 2021 Nov;155:111558. doi: 10.1016/j.exger.2021.111558. Epub 2021 
      Sep 20.