PMID- 34547774
OWN - NLM
STAT- MEDLINE
DCOM- 20210923
LR  - 20221001
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 51
IP  - 3
DP  - 2021 Sep 30
TI  - Comparison of venous, capillary and interstitial blood glucose data measured 
      during hyperbaric oxygen treatment from patients with diabetes mellitus.
PG  - 240-247
LID - 10.28920/dhm51.3.240-247 [doi]
AB  - INTRODUCTION: Patients undergoing hyperbaric oxygen treatments (HBOT) have been 
      shown to experience a reduction in blood glucose (BG) levels during a treatment. 
      This necessitates frequent assessment of BG levels. Continuous glucose monitoring 
      (CGM) may represent an alternative to the current finger prick monitoring method 
      in-chamber, however, continuous sensor glucose (SG) data has not been validated 
      in situ. The aim was to determine the validity of continuous SG and intermittent 
      BG monitoring with serum BG levels in diabetic patients during HBOT. METHODS: 
      Measurements were obtained (finger prick [capillary sample], CGM [interstitial 
      fluid], and serum [venous sample]) at baseline, and at 30, 60, 90 and 120 minutes 
      during the hyperbaric treatment. Data were analysed by calculating intraclass 
      correlation coefficients (ICC) and using mixed effects linear regression. 
      RESULTS: The ICC results (n = 10 patients) between the three methods indicated 
      very high and statistically significant absolute agreement at baseline (pre-dive) 
      (ICC = 0.90, 95% CI 0.74-0.97), at 30 minutes (ICC = 0.85, 95% CI 0.61-0.96), 60 
      minutes (ICC = 0.86, 95% CI 0.58-0.96), 90 minutes (ICC = 0.87, 96% CI 0.63-0.96) 
      and 120 minutes (ICC = 0.90, 95% CI 0.70-0.97). Capillary glucose and CGM SG 
      readings were each within 1 mmol.L-1 on average of the serum glucose reading, 
      with multi-level linear regression finding the average difference between the CGM 
      SG and capillary glucose methods of BG sampling was not statistically significant 
      (P = 0.81). CONCLUSIONS: The CGM SG data were comparable with glucose readings 
      from capillary monitoring. Both CGM and capillary data were consistent with serum 
      values.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Baines, Carol
AU  - Baines C
AD  - Department of Diving and Hyperbaric Medicine, Royal Hobart Hospital, Tasmania, 
      Australia.
AD  - Dr Carol Baines, Department of Diving and Hyperbaric Medicine, Royal Hobart 
      Hospital, 48 Liverpool Street, GPO 1061 Hobart, Tasmania 7001, Australia, 
      carol.baines@ths.tas.gov.au.
FAU - Vicendese, Don
AU  - Vicendese D
AD  - Department of Mathematics and Statistics, La Trobe University, Melbourne, 
      Victoria, Australia.
AD  - Allergy and Lung Health Unit, Melbourne School of Population and Global Health, 
      The University of Melbourne, Victoria, Australia.
FAU - Cooper, David
AU  - Cooper D
AD  - Department of Diving and Hyperbaric Medicine, Royal Hobart Hospital, Tasmania, 
      Australia.
FAU - McGuiness, William
AU  - McGuiness W
AD  - School of Nursing and Midwifery, La Trobe University, Melbourne, Victoria, 
      Australia.
FAU - Miller, Charne
AU  - Miller C
AD  - School of Nursing and Midwifery, La Trobe University, Melbourne, Victoria, 
      Australia.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - 0 (Blood Glucose)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Blood Glucose
MH  - Blood Glucose Self-Monitoring
MH  - *Diabetes Mellitus/therapy
MH  - *Diabetes Mellitus, Type 1
MH  - Humans
MH  - *Hyperbaric Oxygenation
MH  - Oxygen
PMC - PMC8608443
OTO - NOTNLM
OT  - Blood sugar level
OT  - Endocrinology
OT  - Hyperbaric medicine
OT  - Hyperbaric research
OT  - Patient monitoring
COIS- Conflict of interest and funding Patients and clinical staff at the research site 
      who gave their time and support for this project.
EDAT- 2021/09/22 06:00
MHDA- 2021/09/24 06:00
PMCR- 2022/09/30
CRDT- 2021/09/21 20:33
PHST- 2020/08/11 00:00 [received]
PHST- 2021/04/18 00:00 [accepted]
PHST- 2021/09/21 20:33 [entrez]
PHST- 2021/09/22 06:00 [pubmed]
PHST- 2021/09/24 06:00 [medline]
PHST- 2022/09/30 00:00 [pmc-release]
AID - 10.28920/dhm51.3.240-247 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2021 Sep 30;51(3):240-247. doi: 10.28920/dhm51.3.240-247.