PMID- 34552042
OWN - NLM
STAT- MEDLINE
DCOM- 20210924
LR  - 20211117
IS  - 1941-5923 (Electronic)
IS  - 1941-5923 (Linking)
VI  - 22
DP  - 2021 Sep 23
TI  - Treatment of a Gastrointestinal Sarcoidosis Flare: A Multidisciplinary Approach 
      for a Multisystem Disease.
PG  - e932494
LID - 10.12659/AJCR.932494 [doi]
AB  - BACKGROUND Sarcoidosis is a multisystem granulomatous disease with predominant 
      pulmonary involvement and rare gastrointestinal (GI) involvement. The stomach is 
      the most common site when there is GI involvement. Symptomatic gastric 
      sarcoidosis with biopsy-proven disease has rarely been reported and much of the 
      knowledge is from case reports involving white patients. CASE REPORT Our unique 
      case involves a flare of gastric sarcoid in an African American patient with 
      biopsy-proven disease and we highlight our unique broad, multidisciplinary 
      treatment approach that has not been described previously. A 68-year-old woman 
      with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and 
      dysphagia. The diagnosis of gastric sarcoid was made several years prior based on 
      an upper endoscopy biopsy showing non-caseating granulomas in the antrum. She had 
      previously experienced minimal relief of gastric symptoms with corticosteroids. 
      In addition to a steroid taper, the patient experienced improvement in symptoms 
      with a PPI (proton pump inhibitor), bowel regimen, and speech therapy techniques. 
      CONCLUSIONS Gastric symptoms can be a presenting sign for a sarcoid flare in a 
      patient with pulmonary sarcoidosis, which is important for both pulmonologists 
      and gastroenterologists to recognize. In addition to traditional therapy with 
      corticosteroids, our unique broader, multidisciplinary approach with PPI, bowel 
      regimen, and speech therapy techniques such as a liquid wash are important 
      components of treatment for gastric sarcoid that have not been described in 
      previous case reports.
FAU - Nadpara, Neil
AU  - Nadpara N
AD  - Section of Gastroenterology, Lewis Katz School of Medicine at Temple University, 
      Philadelphia, PA, USA.
FAU - Greenwald, Holly S
AU  - Greenwald HS
AD  - Section of Gastroenterology, Lewis Katz School of Medicine at Temple University, 
      Philadelphia, PA, USA.
FAU - Parkman, Henry P
AU  - Parkman HP
AD  - Section of Gastroenterology, Lewis Katz School of Medicine at Temple University, 
      Philadelphia, PA, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20210923
PL  - United States
TA  - Am J Case Rep
JT  - The American journal of case reports
JID - 101489566
SB  - IM
MH  - Abdominal Pain
MH  - Aged
MH  - Biopsy
MH  - Female
MH  - Humans
MH  - *Sarcoidosis/diagnosis/drug therapy
MH  - *Stomach Diseases
PMC - PMC8477980
COIS- Conflict of interest: None declared
EDAT- 2021/09/24 06:00
MHDA- 2021/09/25 06:00
PMCR- 2021/09/23
CRDT- 2021/09/23 05:58
PHST- 2021/09/23 05:58 [entrez]
PHST- 2021/09/24 06:00 [pubmed]
PHST- 2021/09/25 06:00 [medline]
PHST- 2021/09/23 00:00 [pmc-release]
AID - 932494 [pii]
AID - 10.12659/AJCR.932494 [doi]
PST - epublish
SO  - Am J Case Rep. 2021 Sep 23;22:e932494. doi: 10.12659/AJCR.932494.