PMID- 3455212
OWN - NLM
STAT- MEDLINE
DCOM- 19881024
LR  - 20161123
IS  - 0276-3508 (Print)
IS  - 0276-3508 (Linking)
VI  - 6
DP  - 1987
TI  - Steroids and orbital blowout fractures--a new systematic concept in medical 
      management and surgical decision-making.
PG  - 291-300
AB  - Thirty-eight patients with computed tomography (CT)-proven orbital fractures and 
      diplopia were studied prospectively to determine the efficacy of steroids in the 
      medical management of orbital fractures. The protocol is based on double-blind 
      assignments to steroid (ST) and non-steroid (NT) treatment groups. Outcome 
      analysis was based on sorting fractures into three CT classes: I-without soft 
      tissue prolapse (n = 15); II-with soft tissue prolapse (n = 14); and III-CT 
      evidence of inferior rectus entrapment (n = 9). Results included resolution of 
      diplopia without surgery in both ST and NT groups in CT classes I and II. Median 
      time course of resolution was compressed to less than 5 days in the ST treatment 
      group, however, versus 13 days in the nontreatment group. All fractures in class 
      III had residual diplopia with five of nine patients having surgical results that 
      were enhanced in the ST treatment group. In addition, enophthalmos was unmasked 
      in the ST treatment group within 1 week of treatment versus 5 months without 
      treatment. A protocol for medical management and surgical decision-making in 
      blowout fracture is presented.
FAU - Millman, A L
AU  - Millman AL
AD  - New York Eye and Ear Infirmary, New York 10003.
FAU - Della Rocca, R C
AU  - Della Rocca RC
FAU - Spector, S
AU  - Spector S
FAU - Leibeskind, A L
AU  - Leibeskind AL
FAU - Messina, A
AU  - Messina A
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - United States
TA  - Adv Ophthalmic Plast Reconstr Surg
JT  - Advances in ophthalmic plastic and reconstructive surgery
JID - 8213022
RN  - VB0R961HZT (Prednisone)
SB  - IM
MH  - Double-Blind Method
MH  - Eye Diseases/etiology/surgery
MH  - Humans
MH  - Orbital Fractures/complications/diagnostic imaging/*drug therapy/surgery
MH  - Prednisone/*therapeutic use
MH  - Prognosis
MH  - Prospective Studies
MH  - Random Allocation
MH  - Skull Fractures/*drug therapy
MH  - Tomography, X-Ray Computed
EDAT- 1987/01/01 00:00
MHDA- 1987/01/01 00:01
CRDT- 1987/01/01 00:00
PHST- 1987/01/01 00:00 [pubmed]
PHST- 1987/01/01 00:01 [medline]
PHST- 1987/01/01 00:00 [entrez]
PST - ppublish
SO  - Adv Ophthalmic Plast Reconstr Surg. 1987;6:291-300.