PMID- 34552957
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210925
IS  - 2296-861X (Print)
IS  - 2296-861X (Electronic)
IS  - 2296-861X (Linking)
VI  - 8
DP  - 2021
TI  - Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty 
      Management.
PG  - 731356
LID - 10.3389/fnut.2021.731356 [doi]
LID - 731356
AB  - Frailty is an age-related clinical syndrome that may increase the risk of falls, 
      disability, hospitalization, and death in older adults. Delaying the progression 
      of frailty helps improve the quality of life in older adults. Caloric restriction 
      (CR) may extend lifespan and reduce the risk of age-related diseases. However, 
      few studies have explored the relationship between CR and frailty. In this 
      review, we focused on the impact of CR on frailty and aimed to identify potential 
      associated mechanisms. Although CR may help prevent frailty, further studies are 
      required to determine the underlying mechanisms and specific CR regimens suitable 
      for use in humans.
CI  - Copyright (c) 2021 Liu, Li and Ma.
FAU - Liu, Pan
AU  - Liu P
AD  - Department of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, 
      China.
FAU - Li, Yun
AU  - Li Y
AD  - Department of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, 
      China.
FAU - Ma, Lina
AU  - Ma L
AD  - Department of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, 
      China.
AD  - National Clinical Research Center for Geriatric Medicine, Beijing, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210906
PL  - Switzerland
TA  - Front Nutr
JT  - Frontiers in nutrition
JID - 101642264
PMC - PMC8450361
OTO - NOTNLM
OT  - caloric restriction
OT  - frailty
OT  - lifespan
OT  - older adults
OT  - sarcopenia
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2021/09/24 06:00
MHDA- 2021/09/24 06:01
PMCR- 2021/01/01
CRDT- 2021/09/23 06:54
PHST- 2021/06/26 00:00 [received]
PHST- 2021/08/10 00:00 [accepted]
PHST- 2021/09/23 06:54 [entrez]
PHST- 2021/09/24 06:00 [pubmed]
PHST- 2021/09/24 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - 10.3389/fnut.2021.731356 [doi]
PST - epublish
SO  - Front Nutr. 2021 Sep 6;8:731356. doi: 10.3389/fnut.2021.731356. eCollection 2021.