PMID- 34552996 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210925 IS - 2328-8957 (Print) IS - 2328-8957 (Electronic) IS - 2328-8957 (Linking) VI - 8 IP - 9 DP - 2021 Sep TI - The Association of Human Leukocyte Antigen and COVID-19 in Southern China. PG - ofab410 LID - 10.1093/ofid/ofab410 [doi] LID - ofab410 AB - Human leukocyte antigen (HLA) polymorphism is hypothesized to be associated with diverse immune responses toward infectious diseases. Herein, by comparing against multiple subpopulation groups as control, we confirmed that HLA-B*15:27 and HLA-DRB1*04:06 were associated with coronavirus disease 2019 susceptibility in China. Both alleles were predicted to have weak binding affinities toward viral proteins. CI - (c) The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. FAU - Yu, Xueping AU - Yu X AD - Department of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Ho, Kuoting AU - Ho K AD - HI. Q Biomedical Laboratory, Quanzhou, Fujian, China. AD - School of Biomedical Science, Huaqiao University, Quanzhou, Fujian, China. FAU - Shen, Zhongliang AU - Shen Z AD - Department of Infectious Disease, Huashan Hospital, Fudan University, Shanghai, China. FAU - Fu, Xiaoying AU - Fu X AD - HI. Q Biomedical Laboratory, Quanzhou, Fujian, China. FAU - Huang, Hongbo AU - Huang H AD - Department of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Wu, Delun AU - Wu D AD - HI. Q Biomedical Laboratory, Quanzhou, Fujian, China. FAU - Lin, Yancheng AU - Lin Y AD - HI. Q Biomedical Laboratory, Quanzhou, Fujian, China. FAU - Lin, Yijian AU - Lin Y AD - Department of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Chen, Wenhuang AU - Chen W AD - Department of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Su, Milong AU - Su M AD - Department of Clinical Laboratory, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Qiu, Chao AU - Qiu C AD - Department of Infectious Disease, Huashan Hospital, Fudan University, Shanghai, China. FAU - Zhuang, Xibin AU - Zhuang X AD - Department of Respiratory Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. FAU - Su, Zhijun AU - Su Z AD - Department of Infectious Disease, The First Hospital of Quanzhou, affiliated to Fujian Medical University, Quanzhou, Fujian, China. LA - eng PT - Journal Article DEP - 20210806 PL - United States TA - Open Forum Infect Dis JT - Open forum infectious diseases JID - 101637045 PMC - PMC8436377 OTO - NOTNLM OT - COVID-19 OT - HLA OT - SARS-CoV-2 OT - population stratification OT - susceptibility EDAT- 2021/09/24 06:00 MHDA- 2021/09/24 06:01 PMCR- 2021/08/06 CRDT- 2021/09/23 06:54 PHST- 2021/03/12 00:00 [received] PHST- 2021/08/06 00:00 [accepted] PHST- 2021/09/23 06:54 [entrez] PHST- 2021/09/24 06:00 [pubmed] PHST- 2021/09/24 06:01 [medline] PHST- 2021/08/06 00:00 [pmc-release] AID - ofab410 [pii] AID - 10.1093/ofid/ofab410 [doi] PST - epublish SO - Open Forum Infect Dis. 2021 Aug 6;8(9):ofab410. doi: 10.1093/ofid/ofab410. eCollection 2021 Sep.