PMID- 34557461
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210925
IS  - 2296-2360 (Print)
IS  - 2296-2360 (Electronic)
IS  - 2296-2360 (Linking)
VI  - 9
DP  - 2021
TI  - Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant.
PG  - 729917
LID - 10.3389/fped.2021.729917 [doi]
LID - 729917
AB  - The estimated incidence of pediatric testis tumor is 0.5-2.0 per 100,000 
      children, accounting for 1-2% of all pediatric tumors. Mixed germ cell tumors 
      (MGCT) in prepubertal males are exceedingly rare, with only one previous case 
      report found in the literature. We report a case of a MGCT in an infant. For 
      prepubertal males, GCTs typically present with a painless scrotal mass, though 
      trauma, testis torsion and hydrocele are also common presentations. Similar to 
      such tumors in postpubertal males, ultrasonography, computed tomography, and 
      tumor markers are integral to determine the best treatment. The patient described 
      in this report presented with a painless scrotal mass. Following orchiectomy, the 
      patient was found to have MGCT that was limited to the testis. With prudent 
      management, these patients tend to have favorable prognoses.
CI  - Copyright (c) 2021 Talluri, Goedde, Coventry, Rosenberg, Canalichio, Peppas and 
      White.
FAU - Talluri, Sriharsha
AU  - Talluri S
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
FAU - Goedde, Michael A
AU  - Goedde MA
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
FAU - Coventry, Susan
AU  - Coventry S
AD  - Department of Pediatric Anatomic Pathology, Norton Healthcare, Louisville, KY, 
      United States.
FAU - Rosenberg, Eran
AU  - Rosenberg E
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
AD  - Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United 
      States.
FAU - Canalichio, Katie L
AU  - Canalichio KL
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
AD  - Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United 
      States.
FAU - Peppas, Dennis
AU  - Peppas D
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
AD  - Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United 
      States.
FAU - White, Jeffrey T
AU  - White JT
AD  - Department of Urology, University of Louisville, Louisville, KY, United States.
AD  - Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United 
      States.
LA  - eng
PT  - Case Reports
DEP - 20210907
PL  - Switzerland
TA  - Front Pediatr
JT  - Frontiers in pediatrics
JID - 101615492
PMC - PMC8453063
OTO - NOTNLM
OT  - germ cell tumor
OT  - pediatric cancer
OT  - pediatric urology
OT  - surgery
OT  - testicular tumor
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2021/09/25 06:00
MHDA- 2021/09/25 06:01
PMCR- 2021/09/07
CRDT- 2021/09/24 07:10
PHST- 2021/06/24 00:00 [received]
PHST- 2021/08/06 00:00 [accepted]
PHST- 2021/09/24 07:10 [entrez]
PHST- 2021/09/25 06:00 [pubmed]
PHST- 2021/09/25 06:01 [medline]
PHST- 2021/09/07 00:00 [pmc-release]
AID - 10.3389/fped.2021.729917 [doi]
PST - epublish
SO  - Front Pediatr. 2021 Sep 7;9:729917. doi: 10.3389/fped.2021.729917. eCollection 
      2021.