PMID- 34557514
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210925
IS  - 2296-875X (Print)
IS  - 2296-875X (Electronic)
IS  - 2296-875X (Linking)
VI  - 8
DP  - 2021
TI  - Oncofertility Knowledge and Communication: Comparison Between Medical and 
      Surgical Oncologists and Breast Cancer Patients in Academic Chinese Centers.
PG  - 681614
LID - 10.3389/fsurg.2021.681614 [doi]
LID - 681614
AB  - Background: As cancer has become a major public health issue in China, fertility 
      preservation remains limited despite the wide application of Assisted 
      Reproductive Technology (ART) throughout the country. Objective: This study aimed 
      to identify gaps in knowledge and communication as well as referrals in the 
      previous year regarding oncofertility among medical and surgical oncologists and 
      breast cancer patients (BCPs) in Chinese academic settings to target areas of 
      needed improvement. Materials and Methods: A WeChat online questionnaire was 
      designed, distributed, and compared between medical and surgical oncology 
      specialists and reproductive age BCPs in academic teaching settings in Shanghai. 
      Results: Sixty-one medical and surgical oncologists and 125 BCPs responded to the 
      survey. 63.3% of oncologists were familiar with the term "oncofertility" compared 
      to 25.6% of BCPs (p < 0.001). Oncologists were more likely to correctly know the 
      costs associated with treatment (59.0 vs. 32.0%, p < 0.001); patient did not have 
      to be married to undergo oncofertility treatment (50.8 vs. 24.8%, p < 0.001). 
      Both oncologists and BCPs were similarly unlikely to know when patients could 
      utilize cryopreserved tissue in the future (37.7 vs. 22.2%, p = 0.056). While 
      oncologists reported they discussed all oncofertility options (41.0%) and offered 
      psychological counseling (98.4%), significantly fewer BCPs reported receiving 
      information on all options and offered counseling (3.2%, p < 0.001 and 85.6%, p < 
      0.01). Knowledge of oncofertility was the most important predictor for providing 
      and receiving counseling from oncologists [OR = 6.44 (95% CI = 1.59-26.1, p = 
      0.009] and BCPs (OR = 3.73 95% CI: = 1.36-10.2, p = 0.011). Overall, 57.4% of 
      oncologists referred <10 patients and none referred more than 25 patients in the 
      past year. Conclusion: Data suggests a significant knowledge gap and ineffective 
      communication/comprehension exists between academic Chinese oncologists and BCPs. 
      Continued education and raised awareness are needed to optimize utilization of 
      oncofertility services in China.
CI  - Copyright (c) 2021 Biskup, Xin, Li, Zucal, Lu, Sun, Appiah, Lindheim and Zhang.
FAU - Biskup, Ewelina
AU  - Biskup E
AD  - Department of Medical Oncology, Renji Hospital, School of Medicine, Shanghai Jiao 
      Tong University, Shanghai, China.
AD  - Department of Basic and Clinical Medicine, Shanghai University of Medicine and 
      Health Sciences, Shanghai, China.
AD  - International Center for Multimorbidity and Complexity in Medicine (ICMC), 
      Universitat Zurich, Zurich, Switzerland.
FAU - Xin, Zhaochen
AU  - Xin Z
AD  - Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 
      China.
FAU - Li, Rui
AU  - Li R
AD  - Department of Public Health Sciences, University of Rochester School of Medicine 
      and Dentistry, Rochester, NY, United States.
FAU - Zucal, John P
AU  - Zucal JP
AD  - Wright State University Boonshoft School of Medicine, Dayton, OH, United States.
FAU - Lu, Yao
AU  - Lu Y
AD  - Center for Reproductive Medicine, School of Medicine, Renji Hospital, Shanghai 
      Jiao Tong University, Shanghai, China.
AD  - Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, 
      Shanghai, China.
FAU - Sun, Yun
AU  - Sun Y
AD  - Center for Reproductive Medicine, School of Medicine, Renji Hospital, Shanghai 
      Jiao Tong University, Shanghai, China.
AD  - Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, 
      Shanghai, China.
FAU - Appiah, Leslie Coker
AU  - Appiah LC
AD  - Department of Obstetrics and Gynecology, The University of Colorado, Denver, CO, 
      United States.
FAU - Lindheim, Steven R
AU  - Lindheim SR
AD  - Wright State University Boonshoft School of Medicine, Dayton, OH, United States.
AD  - Center for Reproductive Medicine, School of Medicine, Renji Hospital, Shanghai 
      Jiao Tong University, Shanghai, China.
FAU - Zhang, Hongwei
AU  - Zhang H
AD  - Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20210907
PL  - Switzerland
TA  - Front Surg
JT  - Frontiers in surgery
JID - 101645127
PMC - PMC8453209
OTO - NOTNLM
OT  - breast cancer
OT  - breast cancer survivors
OT  - fertility preservation
OT  - oncofertility
OT  - oncologist
OT  - oncology
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2021/09/25 06:00
MHDA- 2021/09/25 06:01
PMCR- 2021/09/07
CRDT- 2021/09/24 07:10
PHST- 2021/04/07 00:00 [received]
PHST- 2021/07/30 00:00 [accepted]
PHST- 2021/09/24 07:10 [entrez]
PHST- 2021/09/25 06:00 [pubmed]
PHST- 2021/09/25 06:01 [medline]
PHST- 2021/09/07 00:00 [pmc-release]
AID - 10.3389/fsurg.2021.681614 [doi]
PST - epublish
SO  - Front Surg. 2021 Sep 7;8:681614. doi: 10.3389/fsurg.2021.681614. eCollection 
      2021.