PMID- 34558476
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20211015
IS  - 2212-554X (Electronic)
IS  - 2212-5531 (Linking)
VI  - 10
IP  - 2
DP  - 2021 Apr-Jun
TI  - Rare manifestation of ocular immune reconstitution inflammatory syndrome from 
      mycobacterium scrofulaceum infection in a patient with AIDS.
PG  - 202-205
LID - 10.4103/ijmy.ijmy_63_21 [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) is a common complication 
      following the initiation of antiretroviral therapy (ART). The most commonly 
      associated pathogens include Mycobacterium tuberculosis and Cryptococcus 
      spp.([1]) IRIS following nontuberculosis mycobacteria (NTM) infection is 
      uncommon, particularly, IRIS following NTM conjunctivitis.([2]) Herein, we 
      present a case of Mycobacterium scrofulaceum conjunctivitis with peripheral 
      ulcerative keratitis and orbital cellulitis in a 45-year-old patient with AIDS 
      who developed IRIS 1 month after starting ART therapy. A combination of both 
      systemic and topical antibiotics together with corticosteroids were used and 
      resulted in a satisfactory outcome with no early recurrence. This case 
      demonstrated a rare ocular IRIS manifestation involving both the external eye and 
      orbit and to the author's knowledge is the first case in the literature in which 
      M. scrofulaceum has been found to be involved in the eye.
FAU - Jiamjunkupt, Thanin
AU  - Jiamjunkupt T
AD  - Department of Medicine, Division of Infectious Diseases, Phramongkutklao 
      Hospital, Bangkok, Thailand.
FAU - Sasiprapha, Nathamon
AU  - Sasiprapha N
AD  - Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand.
FAU - Changpradub, Dhitiwat
AU  - Changpradub D
AD  - Department of Medicine, Division of Infectious Diseases, Phramongkutklao 
      Hospital, Bangkok, Thailand.
FAU - Choontanom, Raveewan
AU  - Choontanom R
AD  - Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand.
FAU - Sansanayudh, Wiwan
AU  - Sansanayudh W
AD  - Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Int J Mycobacteriol
JT  - International journal of mycobacteriology
JID - 101615660
SB  - IM
MH  - *Acquired Immunodeficiency Syndrome/complications
MH  - *HIV Infections/complications/drug therapy
MH  - Humans
MH  - *Immune Reconstitution Inflammatory Syndrome/complications
MH  - Middle Aged
MH  - *Mycobacterium Infections
MH  - Mycobacterium scrofulaceum
OTO - NOTNLM
OT  - HIV
OT  - Mycobacterium scrofulaceum
OT  - immune reconstitution inflammatory syndrome
OT  - nontuberculosis mycobacteria conjunctivitis
COIS- None
EDAT- 2021/09/25 06:00
MHDA- 2021/10/16 06:00
CRDT- 2021/09/24 08:45
PHST- 2021/09/24 08:45 [entrez]
PHST- 2021/09/25 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
AID - IntJMycobacteriol_2021_10_2_202_318385 [pii]
AID - 10.4103/ijmy.ijmy_63_21 [doi]
PST - ppublish
SO  - Int J Mycobacteriol. 2021 Apr-Jun;10(2):202-205. doi: 10.4103/ijmy.ijmy_63_21.