PMID- 34559121
OWN - NLM
STAT- MEDLINE
DCOM- 20211005
LR  - 20231004
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 100
IP  - 38
DP  - 2021 Sep 24
TI  - Risk factors and management of pulmonary infection in elderly patients with heart 
      failure: A retrospective analysis.
PG  - e27238
LID - 10.1097/MD.0000000000027238 [doi]
LID - e27238
AB  - Pulmonary infection is common in patients with heart failure, yet the risk 
      factors remain unclear. We aimed to evaluate the clinical characteristics and 
      risk factors of pulmonary infection in elderly patients with heart failure, to 
      provide reference to the prevention of pulmonary infection.This study was a 
      retrospective study design. We included elderly heart failure patient admitted to 
      our hospital from April 1, 2018 to August 31, 2020. The characteristics and 
      clinical data of pulmonary infection and no infection patients were assessed. 
      Logistic regression analyses were conducted to identify the risk factors of 
      pulmonary infections in patients with heart failure.A total of 201 patients were 
      included. The incidence of pulmonary infection in patients with heart failure was 
      23.88%. There were significant differences in the age, diabetes, New York Heart 
      Association (NYHA) grade, left ventricular ejection fraction (LVEF), C-reactive 
      protein (CRP) between infection and no infection group (all P < .05), and there 
      were not differences in the sex, body mass index, alcohol drinking, smoking, 
      hypertension, hyperlipidemia, length of hospital stay between 2 groups (all 
      P > .05). Logistic regression analyses indicated that age >/=70 years, diabetes, 
      NYHA grade III, LVEF </=55%, and CRP >/=10 mg/L were the independent risk factors of 
      pulmonary infections in patients with heart failure (all P < .05). Pseudomonas 
      aeruginosa (34.48%), Staphylococcus aureus (19.57%), and Klebsiella pneumoniae 
      (15.22%) were the most common 3 pathogens in patients with pulmonary 
      infection.Heart failure patients with age >/=70 years, diabetes, NYHA grade III, 
      LVEF </=55%, and CRP >/=10 mg/L have higher risks of pulmonary infections, preventive 
      measures targeted on those risk factors are needed to reduce pulmonary 
      infections.
CI  - Copyright (c) 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Peng, Qi
AU  - Peng Q
AD  - Cardiac Surgery, Wuhan Asia Heart Hospital, Jianghan District, Wuhan, Hubei, 
      China.
FAU - Yang, Qin
AU  - Yang Q
AUID- ORCID: 0000-0003-2677-9449
AD  - Pharmacy Intravenous Admixture Services, The Sixth Hospital of Wuhan, Affiliated 
      Hospital of Jianghan University, Jiangan District, Wuhan, Hubei, China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - C-Reactive Protein
MH  - Female
MH  - Geriatrics/methods/trends
MH  - Heart Failure/*complications/therapy
MH  - Humans
MH  - Male
MH  - Respiratory Tract Infections/complications/*therapy
MH  - Retrospective Studies
MH  - Risk Factors
PMC - PMC10545257
COIS- The authors report no conflicts of interest.
EDAT- 2021/09/25 06:00
MHDA- 2021/10/06 06:00
PMCR- 2021/09/24
CRDT- 2021/09/24 12:17
PHST- 2020/12/31 00:00 [received]
PHST- 2021/08/21 00:00 [accepted]
PHST- 2021/09/24 12:17 [entrez]
PHST- 2021/09/25 06:00 [pubmed]
PHST- 2021/10/06 06:00 [medline]
PHST- 2021/09/24 00:00 [pmc-release]
AID - 00005792-202109240-00030 [pii]
AID - MD-D-20-12990 [pii]
AID - 10.1097/MD.0000000000027238 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2021 Sep 24;100(38):e27238. doi: 
      10.1097/MD.0000000000027238.