PMID- 34561794 OWN - NLM STAT- MEDLINE DCOM- 20211115 LR - 20211115 IS - 1573-2800 (Electronic) IS - 0004-0002 (Linking) VI - 50 IP - 7 DP - 2021 Oct TI - Variations in Sexual Behaviors by Use of Specific Substances Among Vancouver Gay, Bisexual, and Other Men Who Have Sex with Men: An Event-Level Analysis. PG - 2875-2886 LID - 10.1007/s10508-021-02068-8 [doi] AB - Event-level studies measure substance use and sexual behaviors happening during a specific sexual encounter, ensuring that both variables are temporally paired. This study explored the event-level associations between a range of sexual behaviors (masturbation, anal sex, oral sex, rimming, fisting, sex toys, and group sex) and five sexualized substances (poppers, methamphetamine, GHB, ecstasy/MDMA, and ketamine) used during 11,582 sexual events reported by 762 gay, bisexual, and other men who have sex with men (GBMSM) in Vancouver, Canada. Data were obtained from a prospective cohort of GBMSM who self-reported their behaviors via computer-based questionnaires on their last sexual encounter with up to five of their most recent partners in the past six months. These clustered data were analyzed with multivariable generalized linear mixed models. Participants reported popper use in 16.1% of sexual encounters, methamphetamine in 8.6%, gamma-hydroxybutyrate (GHB) in 4.1%, ecstasy/3,4-methylenedioxymethamphetamine (MDMA) in 3.3%, and ketamine in 1.5%. Condomless receptive anal sex (25.0% of events) was associated with increased odds of using poppers, methamphetamine, GHB, and ecstasy/MDMA. Group sex (13.1% of events) and sharing sex toys (2.0% of events) were more likely with the use of all five substances. Receiving money/drugs/goods in exchange for sex (2.5% of events) was associated with increased odds of poppers, methamphetamine, GHB, and ecstasy/MDMA use. GBMSM living with HIV (29.9% of participants) had higher odds of using poppers, methamphetamine, and GHB, but lower odds of using ecstasy/MDMA. In conclusion, these event-level results suggest public health strategies are needed to address the possible negative impacts of sexualized substance use among GBMSM. CI - (c) 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. FAU - Aguilera-Mijares, Santiago AU - Aguilera-Mijares S AD - Health Services and Systems Innovation, National Institute of Public Health of Mexico, Cuernavaca, Morelos, Mexico. FAU - Sang, Jordan M AU - Sang JM AUID- ORCID: 0000-0001-5649-0326 AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. jsang@cfenet.ubc.ca. FAU - Wang, Lu AU - Wang L AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. FAU - Barath, Justin AU - Barath J AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. FAU - Card, Kiffer G AU - Card KG AUID- ORCID: 0000-0001-6545-1249 AD - Public Health and Social Policy, University of Victoria, Victoria, BC, Canada. FAU - Lachowsky, Nathan J AU - Lachowsky NJ AUID- ORCID: 0000-0002-6336-8780 AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. AD - Public Health and Social Policy, University of Victoria, Victoria, BC, Canada. FAU - Lal, Allan AU - Lal A AUID- ORCID: 0000-0001-7044-2494 AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. FAU - Roth, Eric AU - Roth E AUID- ORCID: 0000-0002-9128-0997 AD - Public Health and Social Policy, University of Victoria, Victoria, BC, Canada. FAU - Hogg, Robert S AU - Hogg RS AUID- ORCID: 0000-0003-3463-5488 AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. AD - Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada. FAU - Moore, David M AU - Moore DM AUID- ORCID: 0000-0003-1078-9247 AD - British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, V6Z 1Y6, Canada. AD - Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada. LA - eng GR - R01DA031055-01A1/DA/NIDA NIH HHS/United States GR - MOP-107544, FDN-143342/CIHR/Canada GR - PJT-153139/CIHR/Canada GR - R01DA031055-01A1/DA/NIDA NIH HHS/United States GR - MOP-107544, FDN-143342/CIHR/Canada GR - PJT-153139/CIHR/Canada PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20210924 PL - United States TA - Arch Sex Behav JT - Archives of sexual behavior JID - 1273516 SB - IM MH - Bisexuality MH - *HIV Infections MH - Homosexuality, Male MH - Humans MH - Male MH - Prospective Studies MH - Risk-Taking MH - Sexual Behavior MH - *Sexual and Gender Minorities MH - *Substance-Related Disorders/epidemiology OTO - NOTNLM OT - Event-level data OT - Gay and bisexual men OT - Sexual behavior OT - Sexual orientation OT - Substance use EDAT- 2021/09/26 06:00 MHDA- 2021/11/16 06:00 CRDT- 2021/09/25 06:23 PHST- 2020/10/22 00:00 [received] PHST- 2021/06/03 00:00 [accepted] PHST- 2021/05/28 00:00 [revised] PHST- 2021/09/26 06:00 [pubmed] PHST- 2021/11/16 06:00 [medline] PHST- 2021/09/25 06:23 [entrez] AID - 10.1007/s10508-021-02068-8 [pii] AID - 10.1007/s10508-021-02068-8 [doi] PST - ppublish SO - Arch Sex Behav. 2021 Oct;50(7):2875-2886. doi: 10.1007/s10508-021-02068-8. Epub 2021 Sep 24.