PMID- 34565454
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210930
IS  - 1710-1484 (Print)
IS  - 1710-1492 (Electronic)
IS  - 1710-1484 (Linking)
VI  - 17
IP  - 1
DP  - 2021 Sep 26
TI  - Anaphylaxis after jellyfish ingestion with no history of stings: a pediatric case 
      report.
PG  - 99
LID - 10.1186/s13223-021-00601-x [doi]
LID - 99
AB  - BACKGROUND: Jellyfish stings are known to induce allergic skin reactions; 
      however, case reports of anaphylaxis after jellyfish ingestion have been 
      increasing, especially in Asian countries. Some cases of anaphylaxis after 
      jellyfish ingestion have been reported in patients with a previous history of 
      frequent jellyfish stings. Herein, we report a pediatric patient with anaphylaxis 
      after jellyfish ingestion with no history of jellyfish stings. CASE PRESENTATION: 
      A 14-year-old girl developed two episodes of anaphylaxis, and her diet diaries 
      revealed that edible jellyfish was common to the meals in both the anaphylaxis 
      events. A skin prick test using five types of edible jellyfish products revealed 
      a positive reaction to some jellyfish, and anaphylaxis was observed after the 
      ingestion of jellyfish in an oral food challenge test. She had no history of 
      jellyfish stings or frequent swimming in the ocean. The basophil activation test 
      showed positive results on stimulation with extracts from various types of edible 
      jellyfish. We observed serum immunoglobulin E (IgE) reactivity to purified 
      jellyfish collagen and jellyfish acid-soluble extracts. Moreover, immunoblotting 
      analysis showed IgE reactivity to two bands at approximately 40 and 70 kDa using 
      purified jellyfish collagen, which may be a causative antigen. CONCLUSIONS: 
      Edible salted jellyfish can be one of the causative foods of anaphylaxis. 
      Clinicians should be aware of the possibility of anaphylactic reactions due to 
      jellyfish ingestion even without a history of jellyfish stings.
CI  - (c) 2021. The Author(s).
FAU - Tsuge, Mitsuru
AU  - Tsuge M
AUID- ORCID: 0000-0001-9010-4708
AD  - Department of Pediatrics, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 700-8558, 
      Okayama, Japan. tsugemitsuru@okayama-u.ac.jp.
FAU - Ikeda, Masanori
AU  - Ikeda M
AD  - Department of Pediatrics, Fukuyama City Hospital, Fukuyama, Japan.
FAU - Mitani, Osamu
AU  - Mitani O
AD  - Department of Pediatrics, Fukuyama City Hospital, Fukuyama, Japan.
FAU - Yasui, Masato
AU  - Yasui M
AD  - Department of Pediatrics, Fukuyama City Hospital, Fukuyama, Japan.
FAU - Tsukahara, Hirokazu
AU  - Tsukahara H
AD  - Department of Pediatrics, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 700-8558, 
      Okayama, Japan.
LA  - eng
PT  - Journal Article
DEP - 20210926
PL  - England
TA  - Allergy Asthma Clin Immunol
JT  - Allergy, asthma, and clinical immunology : official journal of the Canadian 
      Society of Allergy and Clinical Immunology
JID - 101244313
PMC - PMC8474888
OTO - NOTNLM
OT  - Anaphylaxis
OT  - Basophil activation test
OT  - Food allergy
OT  - Immunoglobulin E
OT  - Jellyfish
OT  - Oral food challenge
OT  - Skin prick test
COIS- The authors declare no competing interests.
EDAT- 2021/09/28 06:00
MHDA- 2021/09/28 06:01
PMCR- 2021/09/26
CRDT- 2021/09/27 05:35
PHST- 2021/06/15 00:00 [received]
PHST- 2021/09/11 00:00 [accepted]
PHST- 2021/09/27 05:35 [entrez]
PHST- 2021/09/28 06:00 [pubmed]
PHST- 2021/09/28 06:01 [medline]
PHST- 2021/09/26 00:00 [pmc-release]
AID - 10.1186/s13223-021-00601-x [pii]
AID - 601 [pii]
AID - 10.1186/s13223-021-00601-x [doi]
PST - epublish
SO  - Allergy Asthma Clin Immunol. 2021 Sep 26;17(1):99. doi: 
      10.1186/s13223-021-00601-x.