PMID- 34567356
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210929
IS  - 1939-795X (Print)
IS  - 1939-795X (Electronic)
IS  - 1939-795X (Linking)
VI  - 14
IP  - 2
DP  - 2021
TI  - Reverse Myocardial Remodeling in Hypertrophic Cardiomyopathy: Little Explored 
      Benefit of Exercise.
PG  - 1018-1026
AB  - Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease that causes 
      myocardial remodeling. Physical exercise (PE) is a therapeutic resource used in 
      Supervised Cardiac Rehabilitation (SCR) to improve Quality of Life (QL), reducing 
      cardiovascular morbidity and mortality. Therefore, the aim of this study is to 
      report how SCR using a personalized exercise prescription, promoted Reverse 
      Myocardial Remodeling (RMR), improved functionality and QL of a patient with HCM. 
      This is a case report of a 43-year-old sedentary female patient with a Body Mass 
      Index (BMI) of 24.7 kg/m(2). The patient was diagnosed with Septal Type 
      Asymmetric HCM. Heart Failure (HF) grade III / IV, according to the New York 
      Heart Association (NYHA), was initially treated with 40mg of Propranolol 
      Hydrochloride twice a day, and presented with excessive fatigue, and angina. The 
      echocardiogram showed a final diastolic volume (FDV) of 130 ml, a final systolic 
      volume (FSV) of 44 ml, a left ventricular mass (LVM) of 236 g, interventricular 
      septum thickness of 14 mm, left ventricular posterior wall (LVPW) thickness of 9 
      mm, left atrium diameter 46 mm, left ventricular end diastolic diameter of 52mm, 
      septum/left ventricular wall ratio of 1.55 mm, and ejection fraction (EF) of 66% 
      (Teicholz). It was obtained as a result of decreased FDV 130 vs. 102ml, decreased 
      FSV 44 vs. 32 ml, decreased LVM 236 vs. 201 g, increased EF 66 vs. 69%, 26% 
      improvement in QL, and 50% reduction in the dosage of Propranolol Hydrochloride. 
      These results suggest that a personalized SCR program is an adjuvant treatment 
      capable of promoting RMR and improving QL and functionality in a patient with 
      HCM.
FAU - Petto, Jefferson
AU  - Petto J
AD  - Bahia Social University Center, Salvador, BA, BRAZIL.
AD  - Bahiana School of Medicine and Public Health, Salvador, BA, BRAZIL.
AD  - Actus-Cordios, Cardiovascular and Metabolic Rehabilitation, Salvador, BA, BRAZIL.
FAU - DE Oliveira, Edna C
AU  - DE Oliveira EC
AD  - Bahia Adventist College, Cachoeira, BA, BRAZIL.
FAU - DE Almeida, Raissa V A
AU  - DE Almeida RVA
AD  - Bahia Adventist College, Cachoeira, BA, BRAZIL.
FAU - DE Oliveira, Alice M
AU  - DE Oliveira AM
AD  - Bahia Social University Center, Salvador, BA, BRAZIL.
FAU - DO Amaral, Danielly S N
AU  - DO Amaral DSN
AD  - Bahia Adventist College, Cachoeira, BA, BRAZIL.
FAU - DE Pinna Junior, Braulio J B
AU  - DE Pinna Junior BJB
AD  - Actus-Cordios, Cardiovascular and Metabolic Rehabilitation, Salvador, BA, BRAZIL.
LA  - eng
PT  - Journal Article
DEP - 20210801
PL  - United States
TA  - Int J Exerc Sci
JT  - International journal of exercise science
JID - 101513127
PMC - PMC8439682
OTO - NOTNLM
OT  - Ventricular remodeling
OT  - cardiac rehabilitation
OT  - heart failure
OT  - quality of life
EDAT- 2021/09/28 06:00
MHDA- 2021/09/28 06:01
PMCR- 2021/08/01
CRDT- 2021/09/27 06:08
PHST- 2021/09/27 06:08 [entrez]
PHST- 2021/09/28 06:00 [pubmed]
PHST- 2021/09/28 06:01 [medline]
PHST- 2021/08/01 00:00 [pmc-release]
AID - ijes-14-2-1018 [pii]
PST - epublish
SO  - Int J Exerc Sci. 2021 Aug 1;14(2):1018-1026. eCollection 2021.