PMID- 34581465
OWN - NLM
STAT- MEDLINE
DCOM- 20211231
LR  - 20211231
IS  - 1742-1241 (Electronic)
IS  - 1368-5031 (Linking)
VI  - 75
IP  - 12
DP  - 2021 Dec
TI  - Regular at-home abdominal paracentesis via Tenckhoff catheter in patients with 
      refractory congestive heart failure.
PG  - e14924
LID - 10.1111/ijcp.14924 [doi]
AB  - BACKGROUND: Peritoneal dialysis (PD) is increasingly used for the long-term 
      management of refractory congestive heart failure (CHF). Patients with severe CHF 
      and ascites were treated with regular at-home abdominal paracentesis via 
      Tenckhoff catheter. We investigated the outcome of those patients, aiming to 
      identify potential prognostic factors for longer survival. METHODS: Patients with 
      refractory CHF referred by cardiologists to the PD unit from years 2009 to 2019 
      and treated with regular at-home abdominal paracentesis via Tenckhoff catheter 
      without peritoneal exchanges, were enrolled into this prospective observational 
      study. RESULTS: From the total of 69 refractory CHF patients treated with PD, 18 
      (26%) were managed with regular at-home abdominal paracentesis via Tenckhoff 
      catheter and improved without the need for peritoneal exchanges for fluid removal 
      (no peripheral oedema or pulmonary congestion) or for solutes removal. Median 
      survival of severe CHF patients treated with abdominal paracentesis was 
      13.5 months (0-34 months). Long-term survivors demonstrated significant 
      improvement in the New York Heart Association (NYHA) functional class, 
      improvement in kidney function and decrease in serum C-reactive protein (CRP) and 
      Brain natriuretic peptide (BNP) compared with their baseline status. A subgroup 
      of patients with shorter survival were more likely to have evidence of liver 
      cirrhosis and significantly lower serum sodium compared with patients with longer 
      survival. CONCLUSIONS: Refractory CHF patients with massive ascites could be 
      successfully treated with regular at-home abdominal paracentesis via Tenckhoff 
      catheter. This treatment provides a useful alternative to periodical percutaneous 
      paracentesis on as-needed basis.
CI  - (c) 2021 John Wiley & Sons Ltd.
FAU - Kunin, Margarita
AU  - Kunin M
AD  - Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty 
      of Medicine, Tel-Hashomer, Israel.
FAU - Mini, Sharon
AU  - Mini S
AD  - Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty 
      of Medicine, Tel-Hashomer, Israel.
FAU - Abu-Amer, Nabil
AU  - Abu-Amer N
AD  - Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty 
      of Medicine, Tel-Hashomer, Israel.
FAU - Beckerman, Pazit
AU  - Beckerman P
AD  - Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty 
      of Medicine, Tel-Hashomer, Israel.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20211005
PL  - India
TA  - Int J Clin Pract
JT  - International journal of clinical practice
JID - 9712381
SB  - IM
MH  - Ascites/etiology/therapy
MH  - Catheters
MH  - *Heart Failure/therapy
MH  - Humans
MH  - Paracentesis
MH  - *Peritoneal Dialysis
OTO - NOTNLM
OT  - abdominal paracentesis
OT  - ascites
OT  - congestive heart failure
OT  - peritoneal dialysis
EDAT- 2021/09/29 06:00
MHDA- 2022/01/01 06:00
CRDT- 2021/09/28 09:58
PHST- 2021/09/19 00:00 [revised]
PHST- 2021/05/24 00:00 [received]
PHST- 2021/09/24 00:00 [accepted]
PHST- 2021/09/29 06:00 [pubmed]
PHST- 2022/01/01 06:00 [medline]
PHST- 2021/09/28 09:58 [entrez]
AID - 10.1111/ijcp.14924 [doi]
PST - ppublish
SO  - Int J Clin Pract. 2021 Dec;75(12):e14924. doi: 10.1111/ijcp.14924. Epub 2021 Oct 
      5.