PMID- 34584012
OWN - NLM
STAT- MEDLINE
DCOM- 20220204
LR  - 20231107
IS  - 2332-7812 (Electronic)
IS  - 2332-7812 (Linking)
VI  - 8
IP  - 6
DP  - 2021 Nov
TI  - Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR 
      Encephalitis.
LID - 10.1212/NXI.0000000000001085 [doi]
LID - e1085
AB  - BACKGROUND AND OBJECTIVES: To investigate the genetic determinants of the most 
      common type of antibody-mediated autoimmune encephalitis, anti-NMDA receptor 
      (anti-NMDAR) encephalitis. METHODS: We performed a genome-wide association study 
      in 178 patients with anti-NMDAR encephalitis and 590 healthy controls, followed 
      by a colocalization analysis to identify putatively causal genes. RESULTS: We 
      identified 2 independent risk loci harboring genome-wide significant variants (p 
      < 5 x 10(-8), OR >/= 2.2), 1 on chromosome 15, harboring only the LRRK1 gene, and 1 
      on chromosome 11 centered on the ACP2 and NR1H3 genes in a larger region of high 
      linkage disequilibrium. Colocalization signals with expression quantitative trait 
      loci for different brain regions and immune cell types suggested ACP2, NR1H3, 
      MADD, DDB2, and C11orf49 as putatively causal genes. The best candidate genes in 
      each region are LRRK1, encoding leucine-rich repeat kinase 1, a protein involved 
      in B-cell development, and NR1H3 liver X receptor alpha, a transcription factor 
      whose activation inhibits inflammatory processes. DISCUSSION: This study provides 
      evidence for relevant genetic determinants of antibody-mediated autoimmune 
      encephalitides outside the human leukocyte antigen (HLA) region. The results 
      suggest that future studies with larger sample sizes will successfully identify 
      additional genetic determinants and contribute to the elucidation of the 
      pathomechanism.
CI  - Copyright (c) 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on 
      behalf of the American Academy of Neurology.
FAU - Tietz, Anja K
AU  - Tietz AK
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Angstwurm, Klemens
AU  - Angstwurm K
AUID- ORCID: 0000-0003-3220-8829
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Baumgartner, Tobias
AU  - Baumgartner T
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Doppler, Kathrin
AU  - Doppler K
AUID- ORCID: 0000-0003-2883-0009
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Eisenhut, Katharina
AU  - Eisenhut K
AUID- ORCID: 0000-0001-6448-3126
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Elisak, Martin
AU  - Elisak M
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Franke, Andre
AU  - Franke A
AUID- ORCID: 0000-0003-1530-5811
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Golombeck, Kristin S
AU  - Golombeck KS
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Handreka, Robert
AU  - Handreka R
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Kaufmann, Max
AU  - Kaufmann M
AUID- ORCID: 0000-0002-1954-4425
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Kraemer, Markus
AU  - Kraemer M
AUID- ORCID: 0000-0002-5667-3621
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Kraft, Andrea
AU  - Kraft A
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Lewerenz, Jan
AU  - Lewerenz J
AUID- ORCID: 0000-0002-9272-529X
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Lieb, Wolfgang
AU  - Lieb W
AUID- ORCID: 0000-0003-2544-4460
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Madlener, Marie
AU  - Madlener M
AUID- ORCID: 0000-0002-6299-8238
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Melzer, Nico
AU  - Melzer N
AUID- ORCID: 0000-0002-2420-701X
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Mojzisova, Hana
AU  - Mojzisova H
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Moller, Peter
AU  - Moller P
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Pfefferkorn, Thomas
AU  - Pfefferkorn T
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Pruss, Harald
AU  - Pruss H
AUID- ORCID: 0000-0002-8283-7976
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Rostasy, Kevin
AU  - Rostasy K
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Schnegelsberg, Margret
AU  - Schnegelsberg M
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Schroder, Ina
AU  - Schroder I
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Siebenbrodt, Kai
AU  - Siebenbrodt K
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Suhs, Kurt-Wolfram
AU  - Suhs KW
AUID- ORCID: 0000-0002-8077-481X
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Wickel, Jonathan
AU  - Wickel J
AUID- ORCID: 0000-0002-5854-3759
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Wandinger, Klaus-Peter
AU  - Wandinger KP
AUID- ORCID: 0000-0002-5483-4276
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Leypoldt, Frank
AU  - Leypoldt F
AUID- ORCID: 0000-0002-8972-515X
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany.
FAU - Kuhlenbaumer, Gregor
AU  - Kuhlenbaumer G
AD  - From the Department of Neurology (A.K.T., F.L., G.K.), Kiel University; 
      Department of Neurology (K.A.), University Hospital Regensburg; Department of 
      Epileptiology (T.B.), University Hospital Bonn; Department of Neurology (K.D.), 
      University Hospital Wurzburg; Institute of Clinical Neuroimmunology (K.E.), 
      Biomedical Center and University Hospital, Ludwig Maximilians University, Munich, 
      Germany; Department of Neurology (M.E., H.M.), Charles University, Second Faculty 
      of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of 
      Clinical Molecular Biology (A.F.), Kiel University; Department of Neurology 
      (K.S.G.), University Hospital Munster; Department of Neurology (R.H.), 
      Carl-Thiem-Klinikum Cottbus; Institute of Neuroimmunology and Multiple Sclerosis 
      (INIMS) (Max Kaufmann), University Medical Center Hamburg-Eppendorf; Department 
      of Neurology (Markus Kraemer), Alfried Krupp Hospital, Essen; Department of 
      Neurology (Markus Kraemer, N.M.), Medical Faculty, Heinrich-Heine University 
      Dusseldorf; Department of Neurology (A.K.), Martha-Maria Hospital Halle; 
      Department of Neurology (J.L.), University of Ulm; Institute of Epidemiology 
      (W.L.), Kiel University; Department of Neurology (M.M.), University Hospital 
      Cologne; Department of Neurology and Clinical Neurophysiology (P.M.), Klinikum 
      Weimar; Department of Neurology (T.P.), Klinikum Ingolstadt; Department of 
      Neurology and Experimental Neurology (H.P.), Charite - Universitatsmedizin Berlin 
      and German Center for Neurodegenerative Diseases (DZNE) Berlin; Department of 
      Pediatric Neurology (K.R.), Children's Hospital Datteln, Witten/Herdecke 
      University; Department of Neurology (M.S.), Asklepios Hospitals Schildautal, 
      Seesen; Neuroimmunology (I.S., K.-P.W., F.L.), Institute of Clinical Chemistry, 
      University Hospital Schleswig-Holstein, Kiel/Lubeck; Epilepsy Center Frankfurt 
      Rhine-Main and Department of Neurology (K.S.), Unversity Hospital and Goethe 
      Universiy Frankfurt; Department of Neurology (K.-W.S.), Hannover Medical School; 
      and Section Translational Neuroimmunology (J.W.), Department of Neurology, 
      University Hospital Jena, Germany. g.kuhlenbaeumer@neurologie.uni-kiel.de.
CN  - German Network for Research on Autoimmune Encephalitis (GENERATE)
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20210928
PL  - United States
TA  - Neurol Neuroimmunol Neuroinflamm
JT  - Neurology(R) neuroimmunology & neuroinflammation
JID - 101636388
SB  - IM
MH  - Adult
MH  - Anti-N-Methyl-D-Aspartate Receptor Encephalitis/*genetics
MH  - Case-Control Studies
MH  - Female
MH  - Genetic Loci
MH  - *Genome-Wide Association Study
MH  - Humans
MH  - Male
PMC - PMC8479862
FIR - Kraemer, Markus
IR  - Kraemer M
FIR - Heide, Wolfgang
IR  - Heide W
FIR - Schreiber, Stephan
IR  - Schreiber S
FIR - Entscheva, Marina
IR  - Entscheva M
FIR - Faiss, Jurgen Hartmut
IR  - Faiss JH
FIR - Berger, Robert
IR  - Berger R
FIR - Stammel, Oliver
IR  - Stammel O
FIR - Hoffmann, Anna
IR  - Hoffmann A
FIR - Seidel, Gunter
IR  - Seidel G
FIR - Handreka, Robert
IR  - Handreka R
FIR - Pruss, Harald
IR  - Pruss H
FIR - Priller, Josef
IR  - Priller J
FIR - Finke, Carsten
IR  - Finke C
FIR - Friedemann, Paul
IR  - Friedemann P
FIR - Kortvelyessy, Peter
IR  - Kortvelyessy P
FIR - Stolze, Henning
IR  - Stolze H
FIR - Blaschek, Astrid
IR  - Blaschek A
FIR - Bauer, Sebastian
IR  - Bauer S
FIR - Rosenow, Felix
IR  - Rosenow F
FIR - Siebenbrodt, Kai
IR  - Siebenbrodt K
FIR - Knake, Susanne
IR  - Knake S
FIR - Wunderlich, Benjamin
IR  - Wunderlich B
FIR - Ehrlich, Sven
IR  - Ehrlich S
FIR - Edelhoff, Lena
IR  - Edelhoff L
FIR - Wagner, Judith
IR  - Wagner J
FIR - Trendelenburg, George
IR  - Trendelenburg G
FIR - Gorsler, Anna
IR  - Gorsler A
FIR - Baatz, Sebastian
IR  - Baatz S
FIR - Benesch, Sonka
IR  - Benesch S
FIR - von Mering, Matthias
IR  - von Mering M
FIR - Grau, Armin
IR  - Grau A
FIR - Urbanek, Christian
IR  - Urbanek C
FIR - Reimann, Gernot
IR  - Reimann G
FIR - Neumann-Haefelin, Tobias
IR  - Neumann-Haefelin T
FIR - Pfefferkorn, Thomas
IR  - Pfefferkorn T
FIR - Berning, Sascha
IR  - Berning S
FIR - Kellinghaus, Christoph
IR  - Kellinghaus C
FIR - Nagel, Michael
IR  - Nagel M
FIR - Binder, Andreas
IR  - Binder A
FIR - Dreeesmann, Mona
IR  - Dreeesmann M
FIR - Ismail, Fatme Seval
IR  - Ismail FS
FIR - Oy, Ulrich Hofstadt-van
IR  - Oy UH
FIR - Bien, Christian
IR  - Bien C
FIR - Gebhard, Marcel
IR  - Gebhard M
FIR - Hoffmann, Frank
IR  - Hoffmann F
FIR - Kraft, Andrea
IR  - Kraft A
FIR - Blaes, Franz
IR  - Blaes F
FIR - Bien, Corinna
IR  - Bien C
FIR - Linsa, Andeas
IR  - Linsa A
FIR - Eisenhut, Katharina
IR  - Eisenhut K
FIR - Havla, Joachim
IR  - Havla J
FIR - Thaler, Franziska
IR  - Thaler F
FIR - Kumpfel, Tanja
IR  - Kumpfel T
FIR - Menge, Til
IR  - Menge T
FIR - Friese, Manuel
IR  - Friese M
FIR - Kaufmann, Max
IR  - Kaufmann M
FIR - Stangel, Martin
IR  - Stangel M
FIR - Suhs, Kurt-Wolfram
IR  - Suhs KW
FIR - Trebst, Corinna
IR  - Trebst C
FIR - Obrocki, Jost
IR  - Obrocki J
FIR - Schaumberg, Jens
IR  - Schaumberg J
FIR - Ayzenberg, Ilya
IR  - Ayzenberg I
FIR - Hellwig, Kerstin
IR  - Hellwig K
FIR - Krogias, Christos
IR  - Krogias C
FIR - Ebinger, Friedrich
IR  - Ebinger F
FIR - Finke, Alexander
IR  - Finke A
FIR - Mono, Marie-Luise
IR  - Mono ML
FIR - Bittner, Daniel
IR  - Bittner D
FIR - Bittner, Stefan
IR  - Bittner S
FIR - Tauber, Simone
IR  - Tauber S
FIR - Hausler, Martin
IR  - Hausler M
FIR - Baumgartner, Annette
IR  - Baumgartner A
FIR - Probstel, Anne-Katrin
IR  - Probstel AK
FIR - Ruegg, Stephan
IR  - Ruegg S
FIR - Bernsen, Sarah
IR  - Bernsen S
FIR - Philipsen, Alexandra
IR  - Philipsen A
FIR - Rohner, Hendrik
IR  - Rohner H
FIR - Hillebrand, Philip
IR  - Hillebrand P
FIR - Wopking, Sigrid
IR  - Wopking S
FIR - Karenfort, Michael
IR  - Karenfort M
FIR - Melzer, Nico
IR  - Melzer N
FIR - Meuth, Sven
IR  - Meuth S
FIR - Rauber, Saskia Jania
IR  - Rauber SJ
FIR - Ringelstein, Marius
IR  - Ringelstein M
FIR - Trollmann, Regina
IR  - Trollmann R
FIR - Reinecke, Raphael
IR  - Reinecke R
FIR - Endres, Dominique
IR  - Endres D
FIR - Storm van S Gravesande, Karin
IR  - Storm van S Gravesande K
FIR - von Poderwils, Felix
IR  - von Poderwils F
FIR - Syrbe, Steffen
IR  - Syrbe S
FIR - Balint, Bettina
IR  - Balint B
FIR - Wildemann, Brigitte
IR  - Wildemann B
FIR - Baade-Buttner, Carolin
IR  - Baade-Buttner C
FIR - Geis, Christian
IR  - Geis C
FIR - Ha-Yeun, Chung
IR  - Ha-Yeun C
FIR - Wickel, Jonathan
IR  - Wickel J
FIR - Malter, Michael
IR  - Malter M
FIR - Fazeli, Walid
IR  - Fazeli W
FIR - Stoppe, Muriel
IR  - Stoppe M
FIR - Bergh, Florian Then
IR  - Bergh FT
FIR - Piepgras, Johannes
IR  - Piepgras J
FIR - Held, Valentin
IR  - Held V
FIR - Zieger, Lara
IR  - Zieger L
FIR - Gallus, Marco
IR  - Gallus M
FIR - Grauer, Oliver
IR  - Grauer O
FIR - Kovac, Stjepana
IR  - Kovac S
FIR - Lehric, Christoph
IR  - Lehric C
FIR - Lunemann, Jan
IR  - Lunemann J
FIR - Meyer Zu Horste, Gerd
IR  - Meyer Zu Horste G
FIR - Wiendl, Heinz
IR  - Wiendl H
FIR - Dik, Andre
IR  - Dik A
FIR - Gross, Catharina
IR  - Gross C
FIR - Melzer, Kristin Stefanie
IR  - Melzer KS
FIR - Helena Rau, Johanna Maria
IR  - Helena Rau JM
FIR - Strippel, Christine
IR  - Strippel C
FIR - Monig, Constanze
IR  - Monig C
FIR - Witt, Karsten
IR  - Witt K
FIR - Weissert, Robert
IR  - Weissert R
FIR - Flotats-Bastardas, Marina
IR  - Flotats-Bastardas M
FIR - Schuster, Simon
IR  - Schuster S
FIR - Schroder, Ina
IR  - Schroder I
FIR - Leypoldt, Frank
IR  - Leypoldt F
FIR - van Baalen, Andreas
IR  - van Baalen A
FIR - Dargvainiene, Justina
IR  - Dargvainiene J
FIR - Jansen, Martina
IR  - Jansen M
FIR - Schmutz, Ina-Isabelle
IR  - Schmutz II
FIR - Schreyer, Gesa
IR  - Schreyer G
FIR - Wandinger, Klaus-Peter
IR  - Wandinger KP
FIR - Gul, Halime
IR  - Gul H
FIR - Lewerenz, Jan
IR  - Lewerenz J
FIR - Penner, Loana
IR  - Penner L
FIR - Senel, Makbule
IR  - Senel M
FIR - Tumani, Hayrettin
IR  - Tumani H
FIR - Turedi, Methab
IR  - Turedi M
FIR - Appeltshauser, Luise
IR  - Appeltshauser L
FIR - Doppler, Kathrin
IR  - Doppler K
FIR - Sommer, Claudia
IR  - Sommer C
FIR - Fitzner, Dirk
IR  - Fitzner D
FIR - Schmidt, Jens
IR  - Schmidt J
FIR - Hansen, Niels
IR  - Hansen N
FIR - Rostasy, Kevin
IR  - Rostasy K
FIR - Adelmann, Michael
IR  - Adelmann M
EDAT- 2021/09/30 06:00
MHDA- 2022/02/05 06:00
PMCR- 2021/09/28
CRDT- 2021/09/29 06:03
PHST- 2021/03/16 00:00 [received]
PHST- 2021/07/09 00:00 [accepted]
PHST- 2021/09/29 06:03 [entrez]
PHST- 2021/09/30 06:00 [pubmed]
PHST- 2022/02/05 06:00 [medline]
PHST- 2021/09/28 00:00 [pmc-release]
AID - 8/6/e1085 [pii]
AID - NEURIMMINFL2021038888 [pii]
AID - 10.1212/NXI.0000000000001085 [doi]
PST - epublish
SO  - Neurol Neuroimmunol Neuroinflamm. 2021 Sep 28;8(6):e1085. doi: 
      10.1212/NXI.0000000000001085. Print 2021 Nov.