PMID- 34585886
OWN - NLM
STAT- MEDLINE
DCOM- 20211001
LR  - 20211001
IS  - 0004-5772 (Print)
IS  - 0004-5772 (Linking)
VI  - 69
IP  - 9
DP  - 2021 Sep
TI  - Low Serum Testosterone Levels in Male Patients with Type 2 Diabetes Mellitus as a 
      Risk Factor for Coronary Artery Disease.
PG  - 11-12
AB  - BACKGROUND: Diabetes mellitus is a chronic debilitating illness associated with 
      several complications of which hypogonadism in male patients with type 2 diabetes 
      mellitus (T2DM) is often overlooked but carries a high prevalence and possibly 
      associated with several co-morbidities. OBJECTIVES: To study the correlation of 
      serum testosterone with clinical and biochemical factors in male patients with 
      type 2 diabetes mellitus. METHOD: In our cross-sectional study, we selected a 
      group of 100 patients with type 2 diabetes mellitus (50 each with hypogonadism 
      and 50 with eugonadism) and obtained their biochemical parameters and looked for 
      the prevalence of co-morbid conditions. We did a correlation of serum 
      testosterone with each quantitative variable using Pearson's Coefficient of 
      correlation and multivariable logistic regression analysis was applied. RESULT: 
      Serum testosterone levels were found to be correlated with age, waist 
      circumference, fasting blood sugar, serum triglycerides and eGFR (p<0.05).The 
      prevalence of coronary artery disease was higher in T2DM male patients with 
      hypogonadism as compared eugonadal patients. We found higher odds (1.33 times) 
      for coronary artery disease in male patients with hypogonadism and T2DM as 
      compared to males with T2DM and eugonadism. CONCLUSION: There is a higher risk of 
      coronary artery disease in male patients with T2DM and hypogonadism as compared 
      to males with T2DM and eugonadal status.
CI  - (c) Journal of the Association of Physicians of India 2011.
FAU - Saluja, Manoj
AU  - Saluja M
AD  - Senior Professor, Government Medical College, Kota, Rajasthan.
FAU - Galav, Vishwas
AU  - Galav V
AD  - Senior Resident, Government Medical College, Kota, Rajasthan; Corresponding 
      Author.
FAU - Pillai, Drishya
AU  - Pillai D
AD  - Resident,Government Medical College, Kota, Rajasthan.
FAU - Chittora, Saurabh
AU  - Chittora S
AD  - Assistant Professor, Government Medical College, Kota, Rajasthan.
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Assoc Physicians India
JT  - The Journal of the Association of Physicians of India
JID - 7505585
RN  - 3XMK78S47O (Testosterone)
SB  - IM
MH  - *Coronary Artery Disease/epidemiology/etiology
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Humans
MH  - *Hypogonadism/epidemiology
MH  - Male
MH  - Risk Factors
MH  - Testosterone
EDAT- 2021/09/30 06:00
MHDA- 2021/10/02 06:00
CRDT- 2021/09/29 10:57
PHST- 2021/09/29 10:57 [entrez]
PHST- 2021/09/30 06:00 [pubmed]
PHST- 2021/10/02 06:00 [medline]
PST - ppublish
SO  - J Assoc Physicians India. 2021 Sep;69(9):11-12.