PMID- 34587828
OWN - NLM
STAT- MEDLINE
DCOM- 20211220
LR  - 20220429
IS  - 1525-6065 (Electronic)
IS  - 1064-1955 (Linking)
VI  - 40
IP  - 4
DP  - 2021 Nov
TI  - Predictability of adverse outcomes in hypertensive disorders of pregnancy: a 
      multicenter prospective cohort study.
PG  - 279-287
LID - 10.1080/10641955.2021.1981373 [doi]
AB  - OBJECTIVES: To explore variables associated with adverse maternal/fetal/neonatal 
      outcomes among pregnant/postpartum patients admitted to ICU for hypertensive 
      disorders of pregnancy (HDP). METHODS: Multicenter, prospective, national cohort 
      study. RESULTS: Variables independently associated with maternal/fetal/neonatal 
      mortality among 172 patients were as follows: Acute Physiology and Chronic Health 
      Evaluation-II (APACHE-II)(OR1.20[1.06-1.35]), gestational age 
      (OR0.698[0.59-0.82]) and aspartate aminotransferase (AST)(OR1.004[1.001-1.006]). 
      Positive likelihood ratio for headache, epigastric pain, and visual disturbances 
      to predict composite adverse outcomes were 1.23(1.16-1.30), 0.76(0.59-1.02), and 
      1.1(0.98-1.2), respectively. CONCLUSIONS: Maternal/fetal mortality due to HDP was 
      independently associated with severity of illness on admission, gestational age, 
      and elevated AST. Accuracy of clinical symptoms to predict composite adverse 
      outcomes was low.
FAU - Vasquez, Daniela N
AU  - Vasquez DN
AD  - ICU, Sanatorio Anchorena, City of Buenos Aires, Argentina.
AD  - ICU, Hospital Interzonal De Agudos Gral. San Martin, La Plata, Bs As, Argentina.
FAU - Das Neves, Andrea V
AU  - Das Neves AV
AD  - ICU, Hospital Interzonal De Agudos Gral. San Martin, La Plata, Bs As, Argentina.
FAU - Aphalo, Vanina M
AU  - Aphalo VM
AD  - ICU, Sanatorio Anchorena, City of Buenos Aires, Argentina.
FAU - Vidal, Laura
AU  - Vidal L
AD  - ICU, Hospital Pablo Soria, San Salvador De Jujuy, Jujuy, Argentina.
FAU - Moseinco, Miriam
AU  - Moseinco M
AD  - ICU, Sanatorio Otamendi, City of Buenos Aires, Argentina.
FAU - Lapadula, Jorge
AU  - Lapadula J
AD  - ICU, Hospital Nacional Prof. Alejandro Posadas, Villa Sarmiento, Bs As, 
      Argentina.
FAU - Santa-Maria, Analia
AU  - Santa-Maria A
AD  - ICU, Sanatorio Mitre, City of Buenos Aires, Argentina.
FAU - Zakalik, Graciela
AU  - Zakalik G
AD  - ICU, Hospital Luis Lagomaggiore, City of Mendoza, Mendoza, Argentina.
FAU - Gomez, Raul A
AU  - Gomez RA
AD  - ICU, Sanatorio De Los Arcos, City of Buenos Aires, Argentina.
FAU - Capalbo, Monica
AU  - Capalbo M
AD  - ICU, Hospital Gral De Agudos Jose M.Penna, City of Buenos Aires, Argentina.
FAU - Fernandez, Claudia
AU  - Fernandez C
AD  - ICU, Hospital De Agudos Ramon Madariaga, Posadas, Misiones, Argentina.
FAU - Aguero-Villareal, Enrique
AU  - Aguero-Villareal E
AD  - ICU, Hospital Policlinico Regional Dr. Ramon Carrillo, City of Santiago Del 
      Estero, Santiago Del Estero, Argentina.
FAU - Vommaro, Santiago
AU  - Vommaro S
AD  - ICU, Sanatorio Mater Dei, City of Buenos Aires, Argentina.
FAU - Moretti, Marcelo
AU  - Moretti M
AD  - ICU, Hospital Naval, City of Buenos Aires, Argentina.
FAU - Soli, Silvana B
AU  - Soli SB
AD  - ICU, Sanatorio Julio Corzo, Rosario, Santa Fe, Argentina.
FAU - Ballestero, Florencia
AU  - Ballestero F
AD  - ICU, Hospital Britanico, City of Buenos Aires, Argentina.
FAU - Sottile, Juan P
AU  - Sottile JP
AD  - ICU, Hospital Zonal Bariloche, Bariloche, Rio Negro, Argentina.
FAU - Chapier, Viviana
AU  - Chapier V
AD  - ICU, Hospital Espanol De Mendoza, Godoy Cruz, Mendoza, Argentina.
FAU - Lovesio, Carlos
AU  - Lovesio C
AD  - ICU, Sanatorio Parque, Rosario, Santa Fe, Argentina.
FAU - Santos, Jose
AU  - Santos J
AD  - ICU, Clinica Colon, Mar Del Plata, Bs As, Argentina.
FAU - Bertoletti, Fernando
AU  - Bertoletti F
AD  - ICU, Sanatorio San Jorge, Usuhaia, Tierra Del Fuego, Argentina.
FAU - Mos, Fernando A
AU  - Mos FA
AD  - ICU, Sanatorio Anchorena, City of Buenos Aires, Argentina.
FAU - Risso-Vazquez, Alejandro
AU  - Risso-Vazquez A
AD  - ICU, Sanatorio Otamendi, City of Buenos Aires, Argentina.
FAU - Esteban-Chacon, Mercedes
AU  - Esteban-Chacon M
AD  - ICU, Hospital Nacional Prof. Alejandro Posadas, Villa Sarmiento, Bs As, 
      Argentina.
FAU - Illutovich, Santiago
AU  - Illutovich S
AD  - ICU, Hospital Luis Lagomaggiore, City of Mendoza, Mendoza, Argentina.
FAU - Chapela, Sebastian
AU  - Chapela S
AD  - ICU, Hospital Britanico, City of Buenos Aires, Argentina.
FAU - Loudet, Cecilia I
AU  - Loudet CI
AD  - ICU, Hospital Interzonal De Agudos Gral. San Martin, La Plata, Bs As, Argentina.
FAU - Scapellato, Jose L
AU  - Scapellato JL
AD  - ICU, Sanatorio Anchorena, City of Buenos Aires, Argentina.
FAU - Intile, Alfredo D
AU  - Intile AD
AD  - ICU, Sanatorio Anchorena, City of Buenos Aires, Argentina.
FAU - Estenssoro, Elisa
AU  - Estenssoro E
AD  - ICU, Hospital Interzonal De Agudos Gral. San Martin, La Plata, Bs As, Argentina.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20210929
PL  - England
TA  - Hypertens Pregnancy
JT  - Hypertension in pregnancy
JID - 9421297
SB  - IM
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - Hypertension, Pregnancy-Induced/*epidemiology
MH  - Infant, Newborn
MH  - Pre-Eclampsia/*epidemiology
MH  - Predictive Value of Tests
MH  - Pregnancy
MH  - Pregnancy Outcome/*epidemiology
MH  - Prospective Studies
MH  - Risk Factors
OTO - NOTNLM
OT  - Hypertension
OT  - fetal mortality
OT  - maternal mortality
OT  - predictive value
OT  - pregnancy
OT  - risk factors
EDAT- 2021/10/01 06:00
MHDA- 2021/12/21 06:00
CRDT- 2021/09/30 05:32
PHST- 2021/10/01 06:00 [pubmed]
PHST- 2021/12/21 06:00 [medline]
PHST- 2021/09/30 05:32 [entrez]
AID - 10.1080/10641955.2021.1981373 [doi]
PST - ppublish
SO  - Hypertens Pregnancy. 2021 Nov;40(4):279-287. doi: 10.1080/10641955.2021.1981373. 
      Epub 2021 Sep 29.