PMID- 34590953
OWN - NLM
STAT- MEDLINE
DCOM- 20211015
LR  - 20211015
IS  - 1938-2367 (Electronic)
IS  - 0147-7447 (Linking)
VI  - 44
IP  - 5
DP  - 2021 Sep-Oct
TI  - The Minimally Clinically Important Difference and Substantial Clinical Benefit in 
      Anterior Cruciate Ligament Reconstruction: A Time-to-Achievement Analysis.
PG  - 299-305
LID - 10.3928/01477447-20210819-03 [doi]
AB  - This study examined the time-dependent course of the minimally clinically 
      important difference (MCID) and the substantial clinical benefit (SCB) 
      achievement for International Knee Documentation Committee (IKDC) and Knee Injury 
      and Osteoarthritis Outcome Score (KOOS) subscales following anterior cruciate 
      ligament reconstruction (ACLR). A prospective institutional registry was queried 
      for patients receiving ACLR. The patient-reported outcome measures (PROMs) of 
      interest included the IKDC score and KOOS sub-scales. One hundred forty-three 
      patients (mean+/-SD age, 30.86+/-12.78 years; mean+/-SD body mass index, 25.51+/-4.64 
      kg/m(2)) were included in the analysis. Threshold values for the MCID/SCB were 
      18.9 of 29.6 on IKDC score, 15.7 of 25.3 on KOOS Symptom, 11.9 of 15.5 on KOOS 
      Pain, 13.3 of 20.0 on KOOS ADL, 25.9 of 35.8 on KOOS Quality of Life (QoL), and 
      27.0 of 43.0 on KOOS Sport (area under the curve, 0.74-0.91). Overall, MCID 
      achievement rates increased from 28.0% to 42.7% at 6 months to 41.9% to 70.8% at 
      12 months. Achievement rates of SCB increased from 16.1% to 30.4% at 6 months to 
      29.3% to 51.8% at 12 months. Statistically significant increases in MCID 
      achievement (chi-square=47.95-79.36, all P<.001) and SCB achievement 
      (chi-square=26.02-53.24, all P<.001) occurred from preoperative to 6-month time 
      points across PROMs. From 6-month to 12-month time points, increases in MCID 
      achievement occurred on IKDC score and KOOS QoL (chi-square=5.53-15.11, 
      P<.001-.009). Statistically significant increases in MCID and SCB achievement 
      occurred from preoperative to 6-month time points across IKDC score and KOOS 
      subscales; however, statistically significant increases in achievement rates from 
      6 months to 1 year occurred on IKDC score, KOOS QoL, and KOOS Sport. This study 
      underlines the importance of considering psychological factors and rehabilitative 
      milestones when examining the achievement MCID and SCB after ACLR. [Orthopedics. 
      2021;44(5):299-305.].
FAU - Beletsky, Alexander
AU  - Beletsky A
FAU - Naami, Edmund
AU  - Naami E
FAU - Lu, Yining
AU  - Lu Y
FAU - Polce, Evan M
AU  - Polce EM
FAU - Chahla, Jorge
AU  - Chahla J
FAU - Okoroha, Kelechi R
AU  - Okoroha KR
FAU - Bush-Joseph, Charles
AU  - Bush-Joseph C
FAU - Bach, Bernard
AU  - Bach B
FAU - Yanke, Adam
AU  - Yanke A
FAU - Forsythe, Brian
AU  - Forsythe B
FAU - Cole, Brian J
AU  - Cole BJ
FAU - Verma, Nikhil N
AU  - Verma NN
LA  - eng
PT  - Journal Article
DEP - 20210901
PL  - United States
TA  - Orthopedics
JT  - Orthopedics
JID - 7806107
SB  - IM
MH  - Adult
MH  - *Anterior Cruciate Ligament Injuries/surgery
MH  - *Anterior Cruciate Ligament Reconstruction
MH  - Humans
MH  - Knee Joint/surgery
MH  - Patient Reported Outcome Measures
MH  - Prospective Studies
MH  - Quality of Life
EDAT- 2021/10/01 06:00
MHDA- 2021/10/16 06:00
CRDT- 2021/09/30 12:17
PHST- 2021/09/30 12:17 [entrez]
PHST- 2021/10/01 06:00 [pubmed]
PHST- 2021/10/16 06:00 [medline]
AID - 10.3928/01477447-20210819-03 [doi]
PST - ppublish
SO  - Orthopedics. 2021 Sep-Oct;44(5):299-305. doi: 10.3928/01477447-20210819-03. Epub 
      2021 Sep 1.