PMID- 34591130
OWN - NLM
STAT- MEDLINE
DCOM- 20211102
LR  - 20211102
IS  - 1432-1289 (Electronic)
IS  - 0020-9554 (Linking)
VI  - 62
IP  - 11
DP  - 2021 Nov
TI  - [Atrial fibrillation-Syndromic phenotype in HFpEF or primary disease?].
PG  - 1174-1179
LID - 10.1007/s00108-021-01171-1 [doi]
AB  - Atrial fibrillation and heart failure with preserved left ventricular (LV) 
      ejection fraction (HFpEF) are of high importance in cardiology due to the 
      increasing number of cases. Both diseases can mutually affect each other and 
      important cardiovascular risk factors, e.g. arterial hypertension, diabetes 
      mellitus, obesity and chronic renal insufficiency can be observed with increasing 
      frequency. Currently proven treatment concepts for patients with heart failure 
      and reduced ejection fraction (HFrEF) do not appear to have a comparable 
      prognostic or symptomatic benefit for patients with HFpEF. In addition, there are 
      indications that de novo manifestation of atrial fibrillation in HFpEF patients 
      has been linked to reduced survival. Also, heart and kidney function are 
      negatively affected by atrial fibrillation. Retrospective analyses of patients 
      with HFpEF and atrial fibrillation who had been treated by pulmonary vein 
      isolation could show that interventional treatment of the atrial fibrillation led 
      to an improvement in the New York Heart Association (NYHA) stage and diastolic 
      function. Currently running prospective randomized clinical trials, such as the 
      AMPERE study including patients with HFpEF and atrial fibrillation undergoing 
      pulmonary vein isolation, will hopefully provide reliable prospective randomized 
      data and possibly show an improved symptom control and perhaps also 
      prognostically relevant treatment for HFpEF patients with atrial fibrillation.
CI  - (c) 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.
FAU - Mezger, Matthias
AU  - Mezger M
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland. matthias.mezger@uksh.de.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland. matthias.mezger@uksh.de.
AD  - Campus Lubeck, Universitatsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 
      23538, Lubeck, Deutschland. matthias.mezger@uksh.de.
FAU - Stiermaier, Thomas
AU  - Stiermaier T
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland.
FAU - Reil, Jan-Christian
AU  - Reil JC
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland.
FAU - Tilz, Roland Richard
AU  - Tilz RR
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland.
AD  - Sektion fur Elektrophysiologie, Universitares Herzzentrum Lubeck, Lubeck, 
      Deutschland.
FAU - Lyan, Evgeny
AU  - Lyan E
AD  - Herz- und Gefasszentrum Bad Bevensen, Bad Bevensen, Deutschland.
FAU - Kuck, Karl-Heinz
AU  - Kuck KH
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland.
AD  - Sektion fur Elektrophysiologie, Universitares Herzzentrum Lubeck, Lubeck, 
      Deutschland.
FAU - Eitel, Ingo
AU  - Eitel I
AD  - Abteilung fur Kardiologie, Angiologie und internistische Intensivmedizin, 
      Universitares Herzzentrum Lubeck, Lubeck, Deutschland.
AD  - Deutsches Zentrum fur Herz- Kreislauf- Forschung e.V., DZHK Standort 
      Hamburg/Kiel/Lubeck, Lubeck, Deutschland.
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Vorhofflimmern - syndromaler Phanotyp bei HFpEF oder primare Erkrankung?
DEP - 20210930
PL  - Germany
TA  - Internist (Berl)
JT  - Der Internist
JID - 0264620
SB  - IM
MH  - *Atrial Fibrillation/diagnosis/therapy
MH  - *Heart Failure/diagnosis/therapy
MH  - Humans
MH  - Phenotype
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Stroke Volume
OTO - NOTNLM
OT  - Atrial fibrillation/prognosis
OT  - Cardiovascular risk factors
OT  - Diabetes mellitus, type 2
OT  - Heart failure with preserved ejection fraction
OT  - Renal insufficiency
EDAT- 2021/10/01 06:00
MHDA- 2021/11/03 06:00
CRDT- 2021/09/30 12:24
PHST- 2021/09/01 00:00 [accepted]
PHST- 2021/10/01 06:00 [pubmed]
PHST- 2021/11/03 06:00 [medline]
PHST- 2021/09/30 12:24 [entrez]
AID - 10.1007/s00108-021-01171-1 [pii]
AID - 10.1007/s00108-021-01171-1 [doi]
PST - ppublish
SO  - Internist (Berl). 2021 Nov;62(11):1174-1179. doi: 10.1007/s00108-021-01171-1. 
      Epub 2021 Sep 30.