PMID- 34606839 OWN - NLM STAT- MEDLINE DCOM- 20220124 LR - 20220124 IS - 1096-0953 (Electronic) IS - 0013-9351 (Linking) VI - 204 IP - Pt B DP - 2022 Mar TI - Health risks of inhalation exposure to BTEX in a municipal wastewater treatment plant in Middle East city: Shiraz, Iran. PG - 112155 LID - S0013-9351(21)01456-0 [pii] LID - 10.1016/j.envres.2021.112155 [doi] AB - Benzene, toluene, ethylbenzene, and xylene, known as BTEX, adversely affect human health. This study aimed to measure BTEX concentration and assess the health risk through inhalation exposure to these compounds in a municipal wastewater treatment plant. The ambient air samples were collected using the active sampling method in summer and winter. Sampling sites were close to wastewater treatment units, including bar screen & grit chamber (Site-1), aeration tank & secondary clarifiers (Site-2), anaerobic sludge digester (Site-3), and office & control building (Site-4). Results indicate that the mean levels of benzene and toluene in winter were higher than in summer. The levels of benzene and toluene were below the occupational exposure levels of the American Conference of Governmental Industrial Hygienists (ACGIH) and Occupational Safety and Health Administration (OSHA). The carcinogenic risk (CR) and hazard quotient (HQ) were assessed using the United States Environmental Protection Agency (U.S.EPA) method, and Monte Carlo simulation (MCS) was applied to quantify the uncertainty and sensitivity analysis. The CRs for all sampling sites were below the U.S.EPA threshold limit (1.0 x 10(-4)). The HQ values for benzene nearby Site-2 were above 1.0, indicating inhalation exposure could pose a health hazard. Besides, the HQ results for exposure to toluene in all sampling sites were less than 1.0. The sensitivity analysis had shown that the risk determinant for carcinogenic and non-carcinogenic risk was exposure time, followed by concentration. CI - Copyright (c) 2021 Elsevier Inc. All rights reserved. FAU - Dehghani, Mansooreh AU - Dehghani M AD - Research Center for Health Sciences, Department of Environmental Health, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Mohammadpour, Amin AU - Mohammadpour A AD - Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Abbasi, Alireza AU - Abbasi A AD - Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Rostami, Iman AU - Rostami I AD - Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Gharehchahi, Ehsan AU - Gharehchahi E AD - Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: e.gharehchahi@yahoo.com. FAU - Derakhshan, Zahra AU - Derakhshan Z AD - Research Center for Health Sciences, Department of Environmental Health, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Ferrante, Margherita AU - Ferrante M AD - Environmental and Food Hygiene Laboratories (LIAA) of Department of Medical Sciences, Surgical and Advanced Technologies "G.F. Ingrassia", Hygiene and Public Health, University of Catania, Italy. FAU - Conti, Gea Oliveri AU - Conti GO AD - Environmental and Food Hygiene Laboratories (LIAA) of Department of Medical Sciences, Surgical and Advanced Technologies "G.F. Ingrassia", Hygiene and Public Health, University of Catania, Italy. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20211001 PL - Netherlands TA - Environ Res JT - Environmental research JID - 0147621 RN - 0 (Air Pollutants) SB - IM MH - *Air Pollutants/analysis MH - Environmental Monitoring MH - Humans MH - Inhalation Exposure MH - Iran MH - Middle East MH - Risk Assessment MH - *Water Purification OTO - NOTNLM OT - Air pollution OT - BTEX OT - Risk assessment OT - Wastewater treatment EDAT- 2021/10/05 06:00 MHDA- 2022/01/27 06:00 CRDT- 2021/10/04 20:14 PHST- 2021/06/20 00:00 [received] PHST- 2021/09/27 00:00 [revised] PHST- 2021/09/28 00:00 [accepted] PHST- 2021/10/05 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2021/10/04 20:14 [entrez] AID - S0013-9351(21)01456-0 [pii] AID - 10.1016/j.envres.2021.112155 [doi] PST - ppublish SO - Environ Res. 2022 Mar;204(Pt B):112155. doi: 10.1016/j.envres.2021.112155. Epub 2021 Oct 1.