PMID- 34607289 OWN - NLM STAT- MEDLINE DCOM- 20211129 LR - 20211129 IS - 1872-7727 (Electronic) IS - 0720-048X (Linking) VI - 144 DP - 2021 Nov TI - Percutaneous catheter drainage of pancreatic associated pathologies: A systematic review and meta-analysis. PG - 109978 LID - S0720-048X(21)00459-9 [pii] LID - 10.1016/j.ejrad.2021.109978 [doi] AB - PURPOSE: The main goal of this systematic review was to assess the technical and clinical success, adverse events (AEs), surgery, and overall mortality proportion after percutaneous catheter drainage (PCD) of two pancreatic lesions. METHODS: An extant search in online databases including Scopus, PubMed (Medline), Embase (Elsevier), Web of Science, Cochrane library, and Google Scholar, was conducted to recognize all studies that used PCD intervention in the management of pancreatic necrosis (PN) and pancreatic pseudocysts (PP). Random effects meta-analysis was performed, and Cochrane's Q test and I(2)statistic were utilized to determine heterogeneity. In addition, meta-regression was used to explore the influence of categorical variables on heterogeneity. RESULTS: Thirty-two studies (1398 patients) including PN in 26 (1256 cases, 89.8%) studies and PP in 6 (142 cases, 10.2%) studies were identified. Technical success proportion was 100% (95% confidence interval [CI] 100%-100%, I(2): 0.0%), clinical success 63% (95% CI 55%-71%, I(2): 92.9%), AEs 26% (95% CI 21%-31%, I(2): 78%), surgery after PCD intervention 33% (95% CI 25%-40%, I(2): 92.4%), and overall mortality was 13% (95% CI 9%-17%, I(2): 82.8%). The most common ADs after PCD intervention were development of fistula (106, 42.6%), hemorrhage (44, 17.7%), sepsis (40, 16.1%). CONCLUSION: A significant clinical success proportion with low AEs, surgery, and overall mortality proportion after PCD intervention was found, although the results should be interpreted with caution due to the high heterogeneity. CI - Copyright (c) 2021 Elsevier B.V. All rights reserved. FAU - Keshavarz, Pedram AU - Keshavarz P AD - School of Science and Technology, The University of Georgia, Tbilisi, Georgia; Department of Diagnostic & Interventional Radiology of New Hospitals LTD, Tbilisi, Georgia. FAU - Azrumelashvili, Tamta AU - Azrumelashvili T AD - Department of Diagnostic & Interventional Radiology of New Hospitals LTD, Tbilisi, Georgia; Department of Radiology, Tbilisi State Medical University (TSMU), Tbilisi, Georgia. FAU - Yazdanpanah, Fereshteh AU - Yazdanpanah F AD - Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tabriz, Iran. FAU - Nejati, Seyed Faraz AU - Nejati SF AD - Department of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Ebrahimian Sadabad, Faranak AU - Ebrahimian Sadabad F AD - Department of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Tarjan, Aida AU - Tarjan A AD - Department of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Bazyar, Amir AU - Bazyar A AD - Department of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. FAU - Mizandari, Malkhaz AU - Mizandari M AD - Department of Diagnostic & Interventional Radiology of New Hospitals LTD, Tbilisi, Georgia; Department of Radiology, Tbilisi State Medical University (TSMU), Tbilisi, Georgia. Electronic address: mgmizandari@gmail.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20210928 PL - Ireland TA - Eur J Radiol JT - European journal of radiology JID - 8106411 SB - IM MH - Catheters MH - Drainage MH - Humans MH - Pancreas MH - *Pancreatic Pseudocyst MH - *Pancreatitis, Acute Necrotizing MH - Treatment Outcome OTO - NOTNLM OT - Image-guided Procedure OT - Pancreatic Necrosis OT - Pancreatic Pseudocysts OT - Pancreatitis, Acute Necrotizing OT - Percutaneous Catheter Drainage EDAT- 2021/10/05 06:00 MHDA- 2021/11/30 06:00 CRDT- 2021/10/04 20:31 PHST- 2021/07/07 00:00 [received] PHST- 2021/09/15 00:00 [revised] PHST- 2021/09/23 00:00 [accepted] PHST- 2021/10/05 06:00 [pubmed] PHST- 2021/11/30 06:00 [medline] PHST- 2021/10/04 20:31 [entrez] AID - S0720-048X(21)00459-9 [pii] AID - 10.1016/j.ejrad.2021.109978 [doi] PST - ppublish SO - Eur J Radiol. 2021 Nov;144:109978. doi: 10.1016/j.ejrad.2021.109978. Epub 2021 Sep 28.