PMID- 34609378
OWN - NLM
STAT- MEDLINE
DCOM- 20211007
LR  - 20211007
IS  - 2333-0376 (Electronic)
IS  - 2333-0376 (Linking)
VI  - 35
IP  - 3
DP  - 2021 Summer
TI  - Gluten-Free Diet Reduces Pain in Women with Myofascial Pain in Masticatory 
      Muscles: A Preliminary Randomized Controlled Trial.
PG  - 199-207
LID - 10.11607/ofph.2823 [doi]
AB  - AIMS: To evaluate the efficacy of a gluten-free diet (GFD) as a treatment 
      modality for pain management in women with chronic myofascial pain in masticatory 
      muscles. METHODS: In this randomized controlled trial, 39 female subjects were 
      evaluated according to the Research Diagnostic Criteria for Temporomandibular 
      Disorders (RDC/TMD) and divided into three groups: a healthy group (n = 14; mean 
      +/- SD age = 34.57 +/- 9.14 years); a control group (n = 12; age = 31.50 +/- 7.38 
      years); and an experimental group (n = 13; age 30.00 +/- 7.64 years). The outcome 
      variables were: pain intensity, mechanical pain threshold (MPT), and pressure 
      pain threshold (PPT). MPT was performed on the masseter muscle, and PPT was 
      performed on both the masseter and anterior temporalis muscles. A nutritionist 
      prescribed a 4-week individualized GFD for the experimental group. The healthy 
      group was analyzed only initially, whereas the control and experimental groups 
      were analyzed again after 4 weeks. Data were subjected to statistical analysis 
      with a significance level of 5% (one-way analysis of variance followed by 
      Bonferroni post hoc, paired t, Wilcoxon signed rank, Kruskal-Wallis/Dunn, and 
      Pearson chi-square tests). RESULTS: Participants who underwent a GFD showed 
      reduction in pain intensity (P = .006) and an increase in PPT of the masseter (P 
      = .017) and anterior temporalis (P = .033) muscles. The intervention did not 
      influence the MPT of the masseter muscle (P = .26). In contrast, the control 
      group showed no improvement in any parameter evaluated. CONCLUSION: GFD seemed to 
      reduce pain sensitivity in women with TMD and may be beneficial as an adjunctive 
      therapy for chronic myofascial pain in masticatory muscles; however, further 
      studies in the fields of orofacial pain and nutrition are required.
FAU - Araujo Oliveira Buosi, Juliana
AU  - Araujo Oliveira Buosi J
FAU - Abreu Nogueira, Sandra Maria
AU  - Abreu Nogueira SM
FAU - Sousa, Morgana Pinheiro
AU  - Sousa MP
FAU - Soraya Costa Maia, Carla
AU  - Soraya Costa Maia C
FAU - Regis, Romulo Rocha
AU  - Regis RR
FAU - de Freitas Pontes, Karina Matthes
AU  - de Freitas Pontes KM
FAU - Bonjardim, Leonardo Rigoldi
AU  - Bonjardim LR
FAU - Sales Pinto Fiamengui, Livia Maria
AU  - Sales Pinto Fiamengui LM
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - J Oral Facial Pain Headache
JT  - Journal of oral & facial pain and headache
JID - 101624698
MH  - Adult
MH  - *Diet, Gluten-Free
MH  - Facial Pain
MH  - Female
MH  - Humans
MH  - *Masticatory Muscles
MH  - Pain Measurement
MH  - Pain Threshold
MH  - Young Adult
EDAT- 2021/10/06 06:00
MHDA- 2021/10/08 06:00
CRDT- 2021/10/05 12:20
PHST- 2021/10/05 12:20 [entrez]
PHST- 2021/10/06 06:00 [pubmed]
PHST- 2021/10/08 06:00 [medline]
AID - 10.11607/ofph.2823 [doi]
PST - ppublish
SO  - J Oral Facial Pain Headache. 2021 Summer;35(3):199-207. doi: 10.11607/ofph.2823.