PMID- 34610729
OWN - NLM
STAT- MEDLINE
DCOM- 20211007
LR  - 20211007
IS  - 1827-1928 (Electronic)
IS  - 0022-4707 (Linking)
VI  - 61
IP  - 9
DP  - 2021 Sep
TI  - Timing of creatine supplementation does not influence gains in unilateral muscle 
      hypertrophy or strength from resistance training in young adults: a 
      within-subject design.
PG  - 1219-1225
LID - 10.23736/S0022-4707.20.11668-2 [doi]
AB  - BACKGROUND: Creatine supplementation, in close proximity to resistance training 
      sessions, may be an important strategy to augment muscle accretion and strength. 
      The purpose of this study was to examine the effects of creatine supplementation 
      immediately before compared to immediately after unilateral resistance training 
      on hypertrophy and strength. METHODS: Using a counter-balanced, double-blind, 
      repeated measures within-subject design, ten recreationally active participants 
      (7 males; 3 females; age: 23+/-5 years; height: 174+/-9 cm; body mass: 73.5+/-9.7 kg) 
      were randomized to supplement with creatine monohydrate (0.1 g/kg of body mass) 
      immediately before and placebo immediately after training one side of the body 
      and placebo immediately before and creatine immediately after training the other 
      side of the body on alternate days. Resistance training consisted of elbow 
      flexion and knee extension (3-6 sets at 80% 1-repetition maximum [1-RM]) for 8 
      weeks. Prior to and following training, muscle thickness (elbow flexors and leg 
      extensors; ultrasonography) and strength (1-RM for the elbow flexors and knee 
      extensors) was assessed. RESULTS: There was a significant increase over time for 
      muscle thickness, strength, and relative strength (P<0.01), with no differences 
      between creatine ingestion strategies. Total training volume performed was 
      similar between conditions (P=0.56). CONCLUSIONS: Creatine supplementation, 
      immediately before or immediately after unilateral resistance training, produces 
      similar gains in muscle hypertrophy and strength in young adults.
FAU - Forbes, Scott C
AU  - Forbes SC
AD  - Department of Physical Education Studies, Faculty of Education, Brandon 
      University, Brandon, MB, Canada - ForbesS@brandonu.ca.
FAU - Krentz, Joel R
AU  - Krentz JR
AD  - Department of Physical Education Studies, Faculty of Education, Brandon 
      University, Brandon, MB, Canada.
FAU - Candow, Darren G
AU  - Candow DG
AD  - Faculty of Kinesiology and Health Studies, University of Regina, Regina, SK, 
      Canada.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Italy
TA  - J Sports Med Phys Fitness
JT  - The Journal of sports medicine and physical fitness
JID - 0376337
RN  - MU72812GK0 (Creatine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Creatine
MH  - Dietary Supplements
MH  - Female
MH  - Humans
MH  - Hypertrophy
MH  - Male
MH  - Muscle Strength
MH  - Muscle, Skeletal
MH  - *Resistance Training
MH  - Young Adult
EDAT- 2021/10/07 06:00
MHDA- 2021/10/08 06:00
CRDT- 2021/10/06 04:18
PHST- 2021/10/06 04:18 [entrez]
PHST- 2021/10/07 06:00 [pubmed]
PHST- 2021/10/08 06:00 [medline]
AID - S0022-4707.20.11668-2 [pii]
AID - 10.23736/S0022-4707.20.11668-2 [doi]
PST - ppublish
SO  - J Sports Med Phys Fitness. 2021 Sep;61(9):1219-1225. doi: 
      10.23736/S0022-4707.20.11668-2.