PMID- 346138 OWN - NLM STAT- MEDLINE DCOM- 19780612 LR - 20190705 IS - 0007-1323 (Print) IS - 0007-1323 (Linking) VI - 65 IP - 3 DP - 1978 Mar TI - Prospective randomized multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: interim results. PG - 152-4 AB - In three centres, 222 patients (Birmingham 70, London 87 and Rotterdam 65 patients) with chronic duodenal ulcer were treated by proximal gastrict vagotomy (PGV) (116 patients) or truncal vagotomy and antrectomy (TVA) (106 patients) in a prospective randomized trial. After 1 year 5 recurrent duodenal ulcers (4.3 per cent) have been recorded in the PGV group, compared with 1 (1 per cent) in the TVA group. The reoperation rate was high in both groups-6 after PGV, usually for recurrent ulcer, and 7 after TVA, mostly for gastric retention. PGV showed a marked superiority in the number of patients with a good clinical result Visick I or II) at 1 year after operation, i.e. 82 per cent compared with 56 per cent for TVA. FAU - Dorricott, N J AU - Dorricott NJ FAU - Mcneish, A R AU - Mcneish AR FAU - Alexander-Williams, J AU - Alexander-Williams J FAU - Royston, C M AU - Royston CM FAU - Cooke, W M AU - Cooke WM FAU - Spencer, C J AU - Spencer CJ FAU - De Vries, B C AU - De Vries BC FAU - Muller, H AU - Muller H LA - eng PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PL - England TA - Br J Surg JT - The British journal of surgery JID - 0372553 SB - IM MH - Chronic Disease MH - Clinical Trials as Topic MH - Duodenal Ulcer/*surgery MH - Female MH - Humans MH - Male MH - Postoperative Complications MH - Pyloric Antrum/*surgery MH - Recurrence MH - Vagotomy/*methods EDAT- 1978/03/01 00:00 MHDA- 1978/03/01 00:01 CRDT- 1978/03/01 00:00 PHST- 1978/03/01 00:00 [pubmed] PHST- 1978/03/01 00:01 [medline] PHST- 1978/03/01 00:00 [entrez] AID - 10.1002/bjs.1800650303 [doi] PST - ppublish SO - Br J Surg. 1978 Mar;65(3):152-4. doi: 10.1002/bjs.1800650303.