PMID- 34624199 OWN - NLM STAT- MEDLINE DCOM- 20240327 LR - 20240327 IS - 1744-4160 (Electronic) IS - 1381-3455 (Linking) VI - 130 IP - 2 DP - 2024 Apr TI - Effects of almond consumption on lipid profile in patients with type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials. PG - 128-135 LID - 10.1080/13813455.2021.1987477 [doi] AB - The aim of this meta-analysis was to assess the effects of almond consumption on the lipid profiles of type 2 diabetes mellitus (T2DM) patients. Eligible trials were searched from four electronic databases until Jan 2020. Five eligible articles were included in the final quantitative analysis. Overall, meta-analysis could not show any beneficial effect of almond consumption on total cholesterol (TC) weighted mean difference (WMD: 0.65 mg/dL, 95% CI: -7.52-8.82, p = .87), triglyceride (TG; WMD: 1.59 mg/dL, 95% CI: -21.77-24.96, p = .89), low-density lipoprotein cholesterol (LDL-C; WMD: -5.40 mg/dL, 95% CI: -13.30-2.50, p = .18), and high-density lipoprotein cholesterol (HDL-C; WMD: 1.57 mg/dL, 95% CI: -0.95-4.10, p = .22). However, subgroup analyses showed that serum LDL-C levels were significantly reduced in trials administered > 50 g/d almond. The data suggest that consumption of almond could not improve lipid profile in patients with T2DM. FAU - Wang, Ping AU - Wang P AD - The People's No.1 Hospital of Xiaoshan, Hangzhou, Zhejiang, China. FAU - Sheng, Yingtao AU - Sheng Y AD - The People's No.1 Hospital of Xiaoshan, Hangzhou, Zhejiang, China. FAU - Samadi, Mehnoosh AU - Samadi M AD - Department of Nutritional Sciences, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran. AD - Research Center for Environmental Determinants of Health (RCEDH), School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20211008 PL - England TA - Arch Physiol Biochem JT - Archives of physiology and biochemistry JID - 9510153 RN - 0 (Cholesterol, LDL) RN - 0 (Lipids) RN - 0 (Triglycerides) RN - 0 (Cholesterol, HDL) SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2 MH - *Prunus dulcis MH - Cholesterol, LDL MH - Lipids MH - Triglycerides MH - Cholesterol, HDL MH - Randomized Controlled Trials as Topic OTO - NOTNLM OT - Almond OT - lipid profile OT - meta-analysis OT - type 2 diabetes mellitus EDAT- 2021/10/09 06:00 MHDA- 2024/03/27 06:43 CRDT- 2021/10/08 20:10 PHST- 2024/03/27 06:43 [medline] PHST- 2021/10/09 06:00 [pubmed] PHST- 2021/10/08 20:10 [entrez] AID - 10.1080/13813455.2021.1987477 [doi] PST - ppublish SO - Arch Physiol Biochem. 2024 Apr;130(2):128-135. doi: 10.1080/13813455.2021.1987477. Epub 2021 Oct 8.