PMID- 34624580 OWN - NLM STAT- MEDLINE DCOM- 20211103 LR - 20211103 IS - 1095-8630 (Electronic) IS - 0301-4797 (Linking) VI - 301 DP - 2022 Jan 1 TI - Toward harmonizing global pesticide regulations for surface freshwaters in support of protecting human health. PG - 113909 LID - S0301-4797(21)01971-X [pii] LID - 10.1016/j.jenvman.2021.113909 [doi] AB - To promote international collaboration on environmental pollution management and human health protection, we conducted a global-level study on the management of pesticides for surface freshwater quality. Prior to actions being taken in terms of water treatment or remediation, it is essential that clear and definite regulations be disseminated. In our study, 3094 surface freshwater quality standards for 184 different pesticides were recorded from 53 countries and categorized according to pesticide types and standard types, as well as diverse use of freshwater by humans, and compared water quality standards related to human health. Our results indicate large variations in pesticide regulations, standard types (i.e., long- or short-term water quality standards), and related numerical values. With regard to the protection of human health, the 10 most frequently regulated pesticides account for approximately 47% of the total number of standards across 184 considered pesticides. The average occurrence-weighted variations of standard values (i.e., numerical values provided in a standard in terms of residue limits of a given pesticide in water) for the 20 most regulated persistent organic pollutants (POPs) and other phase-out pesticides (i.e., pesticides not currently-approved for use in agriculture across various countries) are 4.1 and 2.6 orders of magnitude, respectively, with human-exposure related standard values for some pesticides varying with over 3 orders of magnitude (e.g., lindane). In addition, variations in water quality standard values occurred across standard types (e.g., maximum and average), water use types (e.g., unspecified waters and human consumption), and standard values (e.g., pesticide individuals and groups). We conclude that regulatory inconsistencies emphasize the need for international collaboration on domestic water treatment, environmental management as well as specific water quality standards for the wider range of current-use pesticides, thereby improving global harmonization in support of protecting human health. CI - Copyright (c) 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. FAU - Li, Zijian AU - Li Z AD - School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, 518107, China. Electronic address: lizijian3@mail.sysu.edu.cn. FAU - Fantke, Peter AU - Fantke P AD - Quantitative Sustainability Assessment, Department of Technology, Management and Engineering, Technical University of Denmark, 2800, Kgs, Lyngby, Denmark. LA - eng PT - Journal Article PT - Review DEP - 20211006 PL - England TA - J Environ Manage JT - Journal of environmental management JID - 0401664 RN - 0 (Pesticides) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Agriculture MH - Environmental Monitoring MH - Fresh Water MH - Humans MH - *Pesticides/analysis MH - *Water Pollutants, Chemical/analysis MH - *Water Purification OTO - NOTNLM OT - Environmental management OT - Political globalization OT - Water quality standard EDAT- 2021/10/09 06:00 MHDA- 2021/11/04 06:00 CRDT- 2021/10/08 20:18 PHST- 2021/06/23 00:00 [received] PHST- 2021/10/03 00:00 [revised] PHST- 2021/10/03 00:00 [accepted] PHST- 2021/10/09 06:00 [pubmed] PHST- 2021/11/04 06:00 [medline] PHST- 2021/10/08 20:18 [entrez] AID - S0301-4797(21)01971-X [pii] AID - 10.1016/j.jenvman.2021.113909 [doi] PST - ppublish SO - J Environ Manage. 2022 Jan 1;301:113909. doi: 10.1016/j.jenvman.2021.113909. Epub 2021 Oct 6.