PMID- 34624746
OWN - NLM
STAT- MEDLINE
DCOM- 20211119
LR  - 20211119
IS  - 1876-2026 (Electronic)
IS  - 1876-2018 (Linking)
VI  - 66
DP  - 2021 Dec
TI  - Sensitivity to change and minimal clinically important difference of Edinburgh 
      postnatal depression scale.
PG  - 102873
LID - S1876-2018(21)00329-4 [pii]
LID - 10.1016/j.ajp.2021.102873 [doi]
AB  - OBJECTIVE: Edinburgh Postnatal Depression Scale (EPDS) was widely used in 
      measuring depression symptoms among pregnant women. However, it is still unclear 
      about the sensitivity to change and minimal clinically important difference 
      (MCID) for EPDS. METHODS: Based on data from an eight-week smartphone-based 
      mindfulness intervention, scores of EPDS, 9-item Patient Health Questionnaire 
      (PHQ-9), and 7-item Generalized Anxiety Disorder (GAD-7) before and after the 
      intervention were collected. Three self-appraisal questions were collected after 
      the intervention. The sensitivity to change of EPDS was determined by 
      correlations between changes in PHQ-9, GAD-7, and EPDS. MCID for EPDS was 
      determined by distribution-based method (0.5 standard deviation and standard 
      error of the measurement) and anchor-based method (PHQ-9, GAD-7, and 
      participants' self-appraisal served as anchors). The final MCID value for EPDS 
      was calculated by average scores of the two methods. 117 women with pre-post 
      assessments were included in the analysis. RESULTS: EPDS score changes from 
      baseline to post-intervention were correlated with pre-post change in PHQ-9 and 
      GAD-7 (r = 0.540, P < 0.001). The average MCID for EPDS score was found to be 4 
      points (ranging from -1.45 to -6.5 points) for improvement and 3 points for 
      worsening (ranging from 1.45 to 3.5 points). CONCLUSION: The EPDS is sensitive to 
      detect the changes in maternal depressive symptoms during pregnancy through a 
      mindfulness course of interventions. Four points for improvement and three points 
      for worsening are recommended as MCID for EPDS.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Mao, Fangxiang
AU  - Mao F
AD  - School of Nursing and Rehabilitation, Shandong University, China.
FAU - Sun, Yaoyao
AU  - Sun Y
AD  - School of Nursing and Rehabilitation, Shandong University, China.
FAU - Wang, Juan
AU  - Wang J
AD  - School of Nursing and Rehabilitation, Shandong University, China.
FAU - Huang, Yongqi
AU  - Huang Y
AD  - School of Nursing and Rehabilitation, Shandong University, China.
FAU - Lu, Yane
AU  - Lu Y
AD  - School of Nursing and Rehabilitation, Shandong University, China.
FAU - Cao, Fenglin
AU  - Cao F
AD  - School of Nursing and Rehabilitation, Shandong University, China. Electronic 
      address: fenglin@sdu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20210929
PL  - Netherlands
TA  - Asian J Psychiatr
JT  - Asian journal of psychiatry
JID - 101517820
SB  - IM
MH  - Anxiety Disorders
MH  - Depression
MH  - *Depression, Postpartum/diagnosis/therapy
MH  - Female
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - Patient Health Questionnaire
MH  - Pregnancy
MH  - Psychiatric Status Rating Scales
OTO - NOTNLM
OT  - Depression
OT  - Minimal clinically important difference
OT  - Pregnancy
OT  - Psychometrics
EDAT- 2021/10/09 06:00
MHDA- 2021/11/20 06:00
CRDT- 2021/10/08 20:29
PHST- 2021/08/28 00:00 [received]
PHST- 2021/09/14 00:00 [revised]
PHST- 2021/09/27 00:00 [accepted]
PHST- 2021/10/09 06:00 [pubmed]
PHST- 2021/11/20 06:00 [medline]
PHST- 2021/10/08 20:29 [entrez]
AID - S1876-2018(21)00329-4 [pii]
AID - 10.1016/j.ajp.2021.102873 [doi]
PST - ppublish
SO  - Asian J Psychiatr. 2021 Dec;66:102873. doi: 10.1016/j.ajp.2021.102873. Epub 2021 
      Sep 29.