PMID- 34627698
OWN - NLM
STAT- MEDLINE
DCOM- 20211122
LR  - 20211122
IS  - 1590-3729 (Electronic)
IS  - 0939-4753 (Linking)
VI  - 31
IP  - 11
DP  - 2021 Oct 28
TI  - Quantity and quality of complementary and alternative medicine recommendations in 
      clinical practice guidelines for type 2 diabetes mellitus: A systematic review.
PG  - 3004-3015
LID - S0939-4753(21)00350-1 [pii]
LID - 10.1016/j.numecd.2021.07.029 [doi]
AB  - AIMS: Approximately 70% of Americans with diabetes have used complementary and 
      alternative medicine (CAM) in the past year. Healthcare providers often receive 
      minimal training on these therapies and subsequently rely on clinical practice 
      guidelines (CPGs) to supplement their knowledge about the safe and effective use 
      of CAM for the treatment/management of type 2 diabetes mellitus (T2DM). The 
      purpose of this systematic review is to determine the quantity and assess the 
      quality of CAM recommendations in CPGs for the treatment and/or management of 
      T2DM. DATA SYNTHESIS: MEDLINE, EMBASE, and CINAHL were systematically searched 
      from 2009 to 2020, in addition to the Guidelines International Network and the 
      National Center for Complementary and Integrative Health websites. CPGs 
      containing treatment and/or management recommendations for T2DM were eligible; 
      those with CAM recommendations were quality-assessed with the AGREE II instrument 
      twice, once for the overall CPG and once for the CAM sections. Twenty-seven CPGs 
      were deemed eligible, of which 7 made CAM recommendations. Mean scaled domain 
      percentages were (overall, CAM): scope and purpose (89.7%, 79.8%), clarity of 
      presentation (85.7%, 48.4%), stakeholder involvement (67.9%, 28.2%), 
      applicability (54.8%, 20.2%), rigour of development (49.7%, 35.7%), and editorial 
      independence (44.1%, 44.1%). CONCLUSIONS: Quality varied within and across CPGs; 
      domain scores across CAM sections generally scored lower than the overall CPG. 
      Given that CAM therapies for T2DM are only represented in one-quarter of eligible 
      CPGs and are of lower quality, a knowledge gap exists for healthcare providers 
      who seek evidence-based information on this topic in order to effectively counsel 
      inquiring patients.
CI  - Copyright (c) 2021 The Italian Diabetes Society, the Italian Society for the Study 
      of Atherosclerosis, the Italian Society of Human Nutrition and the Department of 
      Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. 
      All rights reserved.
FAU - Ng, Jeremy Y
AU  - Ng JY
AD  - Department of Health Research Methods, Evidence, and Impact, Faculty of Health 
      Sciences, McMaster University, Hamilton, Ontario, Canada. Electronic address: 
      ngjy2@mcmaster.ca.
FAU - Verma, Kiran D
AU  - Verma KD
AD  - Department of Health Research Methods, Evidence, and Impact, Faculty of Health 
      Sciences, McMaster University, Hamilton, Ontario, Canada. Electronic address: 
      vermak10@mcmaster.ca.
FAU - Gilotra, Kevin
AU  - Gilotra K
AD  - Department of Health Research Methods, Evidence, and Impact, Faculty of Health 
      Sciences, McMaster University, Hamilton, Ontario, Canada. Electronic address: 
      gilotrak@mcmaster.ca.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
DEP - 20210804
PL  - Netherlands
TA  - Nutr Metab Cardiovasc Dis
JT  - Nutrition, metabolism, and cardiovascular diseases : NMCD
JID - 9111474
SB  - IM
MH  - Complementary Therapies/adverse effects/*standards
MH  - Diabetes Mellitus, Type 2/diagnosis/*therapy
MH  - Humans
MH  - Practice Guidelines as Topic/*standards
MH  - Quality Assurance, Health Care/*standards
MH  - Quality Indicators, Health Care/*standards
OTO - NOTNLM
OT  - AGREE II
OT  - Clinical practice guideline
OT  - Complementary and alternative medicine
OT  - Diabetes
OT  - Systematic review
OT  - Type 2 diabetes mellitus
COIS- Declaration of competing interest The authors declare that they have no competing 
      interests.
EDAT- 2021/10/11 06:00
MHDA- 2021/11/23 06:00
CRDT- 2021/10/10 20:44
PHST- 2021/05/02 00:00 [received]
PHST- 2021/07/07 00:00 [revised]
PHST- 2021/07/26 00:00 [accepted]
PHST- 2021/10/11 06:00 [pubmed]
PHST- 2021/11/23 06:00 [medline]
PHST- 2021/10/10 20:44 [entrez]
AID - S0939-4753(21)00350-1 [pii]
AID - 10.1016/j.numecd.2021.07.029 [doi]
PST - ppublish
SO  - Nutr Metab Cardiovasc Dis. 2021 Oct 28;31(11):3004-3015. doi: 
      10.1016/j.numecd.2021.07.029. Epub 2021 Aug 4.