PMID- 34632920
OWN - NLM
STAT- MEDLINE
DCOM- 20220208
LR  - 20220428
IS  - 1651-2251 (Electronic)
IS  - 0001-6489 (Linking)
VI  - 141
IP  - 10
DP  - 2021 Oct
TI  - Role of laryngopharyngeal reflux (LPR) in complications after tonsillectomy in 
      adult patients.
PG  - 948-952
LID - 10.1080/00016489.2021.1982148 [doi]
AB  - BACKGROUND: Tonsillectomy and tonsillectomy with adenoidectomy are among the most 
      common surgical procedures in otolaryngology practice, but the complications, 
      especially the postoperative bleeding, are seriously troubling surgeons. Some 
      authors had identified that gastroesophageal reflux and LPR are both risk factors 
      for complications in tonsillectomy of children patients. AIMS/OBJECTIVES: 
      Therefore, we designed this prospective study to assess the role of LPR in the 
      development of complications following tonsillectomy in adult patients. We want 
      to provide a basis for future clinical practice. MATERIAL AND METHODS: We 
      recruited a totally of 150 adult patients (18-60 years old) who had an indication 
      of tonsillectomy because of recurrent tonsillitis and divided them into two 
      groups, the laryngopharyngeal reflux (LPR) group and the control group identified 
      by the results of Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). The 
      complications that were observed and evaluated were pain, hemorrhage, fever, 
      infection, and pulmonary problems. RESULT: All the patients complained of pain 
      after surgery. The duration of the pain in the LPR group was much longer than 
      that of the control group. In the LPR group, patients had a similar pain level on 
      the first day after surgery. However, on the 7th day and 14th day after surgery, 
      the pain level was obviously higher than that of the control group. We found that 
      the body temperature mildly rose on the 1st day after surgery and gradually fell 
      to normal level in both groups. No cases had bleeding within 24 h after surgery. 
      There were nine cases of bleeding in the LPR group, while only one case of 
      bleeding occurred in the control group. There were no cases of infection or 
      pulmonary complications in either group. CONCLUSIONS AND SIGNIFICANCE: LPR is 
      closely related to the complications followed by tonsillectomy and we also 
      suggest that high dosages of proton pump inhibitors (PPI), alkaline water, and 
      alginates should be prescribed to the patients with LPR during the perioperative 
      period.
FAU - Tan, Jie
AU  - Tan J
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Li, Xueshi
AU  - Li X
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Zhao, Yixin
AU  - Zhao Y
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Wang, Yuguang
AU  - Wang Y
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Shen, Jinxia
AU  - Shen J
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Zhang, Lihong
AU  - Zhang L
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Han, Lin
AU  - Han L
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
FAU - Yu, Lisheng
AU  - Yu L
AD  - Department of Otorhinolaryngology Head and Neck Surgery, Peking University 
      People's Hospital, Peking University, Beijing, China.
LA  - eng
PT  - Journal Article
DEP - 20211010
PL  - England
TA  - Acta Otolaryngol
JT  - Acta oto-laryngologica
JID - 0370354
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Laryngopharyngeal Reflux/*complications
MH  - Male
MH  - Postoperative Complications
MH  - Prospective Studies
MH  - Risk Factors
MH  - Tonsillectomy/*adverse effects
OTO - NOTNLM
OT  - Laryngopharyngeal reflux
OT  - complications
OT  - tonsillectomy
EDAT- 2021/10/12 06:00
MHDA- 2022/02/09 06:00
CRDT- 2021/10/11 08:47
PHST- 2021/10/12 06:00 [pubmed]
PHST- 2022/02/09 06:00 [medline]
PHST- 2021/10/11 08:47 [entrez]
AID - 10.1080/00016489.2021.1982148 [doi]
PST - ppublish
SO  - Acta Otolaryngol. 2021 Oct;141(10):948-952. doi: 10.1080/00016489.2021.1982148. 
      Epub 2021 Oct 10.