PMID- 34635223
OWN - NLM
STAT- MEDLINE
DCOM- 20211013
LR  - 20211013
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 236
DP  - 2022 Jan 1
TI  - Simultaneous preconcentration and determination of sulfonamide antibiotics in 
      milk and yoghurt by dynamic pH junction focusing coupled with capillary 
      electrophoresis.
PG  - 122833
LID - S0039-9140(21)00754-2 [pii]
LID - 10.1016/j.talanta.2021.122833 [doi]
AB  - A dynamic pH junction was used in capillary electrophoresis (CE-DAD) to on-line 
      preconcentrate, separate, and determine trace amounts of sulfonamide antibiotics 
      (SAs) in milk and yoghurt samples in this study. A sample matrix with 0.15% 
      acetic acid and 10% methanol (MeOH) at a pH of 4.0, and a background electrolyte 
      (BGE) that contained 35 mM sodium citrate with 10% MeOH at a pH of 8.5, and an 
      acidic barrage of 0.4% acetic acid with 10% MeOH at a pH of 2.5 were utilised to 
      achieve a stacking effect for SAs through a dynamic pH junction. Under optimised 
      conditions, the proposed preconcentration method showed good linearity 
      (30-500 ng/mL, r(2) >/= 0.9940), low limits of detection (LODs) of 4.1-6.3 ng/mL, 
      and acceptable analytes recovery (81.2-106.9%) with relative standard deviations 
      (RSDs) within 5.3-13.7 (n = 9). The limits of quantification (LOQs) were below 
      the maximum residue limit approved by the European Union (EU) in this type of 
      matrices. Sensitivity enhancement factors of up to 129 were reached with the 
      optimised dynamic pH junction using CE with a diode array detector (DAD). The 
      method was used to determine SAs in fresh milk, low-fat milk, full-cream milk, 
      and yoghurt samples.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Semail, Nadhiratul-Farihin
AU  - Semail NF
AD  - Integrative Medicine Clusters, Advanced Medical and Dental Institute (AMDI), 
      Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia.
FAU - Abdul Keyon, Aemi Syazwani
AU  - Abdul Keyon AS
AD  - Department of Chemistry, Faculty of Science and Centre for Sustainable 
      Nanomaterials, Ibnu Sina Institute for Scientific and Industrial Research, 
      Universiti Teknologi Malaysia, 81310, UTM, Johor Bahru, Johor, Malaysia.
FAU - Saad, Bahruddin
AU  - Saad B
AD  - Fundamental & Applied Sciences Department, Universiti Teknologi PETRONAS, 32601, 
      Seri Iskandar, Perak Darul Ridzuan, Malaysia.
FAU - Kamaruzaman, Sazlinda
AU  - Kamaruzaman S
AD  - Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400, 
      UPM Serdang, Selangor Darul Ehsan, Malaysia.
FAU - Mohamad Zain, Nur Nadhirah
AU  - Mohamad Zain NN
AD  - Integrative Medicine Clusters, Advanced Medical and Dental Institute (AMDI), 
      Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia.
FAU - Lim, Vuanghao
AU  - Lim V
AD  - Integrative Medicine Clusters, Advanced Medical and Dental Institute (AMDI), 
      Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia.
FAU - Miskam, Mazidatulakmam
AU  - Miskam M
AD  - School of Chemical Sciences, Universiti Sains Malaysia, 11800, USM Pulau Pinang, 
      Malaysia.
FAU - Wan Abdullah, Wan Nazwanie
AU  - Wan Abdullah WN
AD  - School of Chemical Sciences, Universiti Sains Malaysia, 11800, USM Pulau Pinang, 
      Malaysia.
FAU - Yahaya, Noorfatimah
AU  - Yahaya N
AD  - Integrative Medicine Clusters, Advanced Medical and Dental Institute (AMDI), 
      Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia. 
      Electronic address: noorfatimah@usm.my.
FAU - Chen, David D Y
AU  - Chen DDY
AD  - Department of Chemistry, University of British Columbia, Vancouver, V6T 1Z1, 
      Canada. Electronic address: chen@chem.ubc.ca.
LA  - eng
PT  - Journal Article
DEP - 20210831
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Sulfonamides)
SB  - IM
MH  - Animals
MH  - *Anti-Bacterial Agents
MH  - Electrophoresis, Capillary
MH  - Hydrogen-Ion Concentration
MH  - Milk
MH  - Sulfonamides
MH  - *Yogurt
OTO - NOTNLM
OT  - Capillary electrophoresis
OT  - Dynamic pH junction
OT  - Milk
OT  - Online preconcentration
OT  - Sulfonamide antibiotics
OT  - Yoghurt
EDAT- 2021/10/13 06:00
MHDA- 2021/10/14 06:00
CRDT- 2021/10/12 05:42
PHST- 2021/07/07 00:00 [received]
PHST- 2021/08/27 00:00 [revised]
PHST- 2021/08/28 00:00 [accepted]
PHST- 2021/10/12 05:42 [entrez]
PHST- 2021/10/13 06:00 [pubmed]
PHST- 2021/10/14 06:00 [medline]
AID - S0039-9140(21)00754-2 [pii]
AID - 10.1016/j.talanta.2021.122833 [doi]
PST - ppublish
SO  - Talanta. 2022 Jan 1;236:122833. doi: 10.1016/j.talanta.2021.122833. Epub 2021 Aug 
      31.