PMID- 34636710
OWN - NLM
STAT- MEDLINE
DCOM- 20220318
LR  - 20220429
IS  - 1473-0766 (Electronic)
IS  - 0951-3590 (Linking)
VI  - 38
IP  - 1
DP  - 2022 Jan
TI  - Effectiveness of system-based intervention in reducing incidence of type 2 
      diabetes and to improve the postnatal metabolic profiles in women with 
      gestational diabetes mellitus: a randomized controlled study.
PG  - 55-62
LID - 10.1080/09513590.2021.1988561 [doi]
AB  - AIM: The objective of this study was to determine the effectiveness of 
      system-based intervention in reducing the incidence of diabetes and to improve 
      the postnatal metabolic profiles among women with gestational diabetes mellitus 
      (GDM). MATERIALS AND METHODS: For women in the intervention arm (n = 130), they 
      received one session of individualized health education at 36 gestational weeks, 
      a booklet of diabetes prevention, five-session of postpartum booster educational 
      program which were conducted including 1 session of dietary and exercise 
      counseling by dietician and physiotherapist at 6 weeks postpartum. For women in 
      the control group (n = 168), standard treatment whereby they had received group 
      therapy on diet and physical activity modification by dietician and staff nurses 
      during the antenatal period. RESULTS: There were no significant differences in 
      baseline characteristics between groups for most of the variables examined except 
      for educational level which the control group had a higher education than the 
      intervention group. The women assigned to system-based intervention have a 
      significant difference to GDM women who were assigned to the control group for 
      LDL and HDL but not in anthropometric measurements, blood pressure, glucose 
      index, total cholesterol, and triglyceride. In addition, it was found that the 
      incidence of Type 2 diabetes mellitus (T2DM) 2 years after delivery was 20% in 
      the intervention arm compared to 17% in the control arm. CONCLUSION: The 
      system-based intervention was not statistically superior to the control 
      intervention as there is no difference in terms of incidence of T2DM between the 
      intervention and control group. We, therefore, suggested that more intensive 
      interventions are needed to prevent GDM from developing into T2DM.
FAU - Lee, Kai Wei
AU  - Lee KW
AUID- ORCID: 0000-0001-9737-8066
AD  - Department of Pre-Clinical Sciences, Faculty of Medicine and Health Sciences, 
      Universiti Tunku Abdul Rahman, Kajang, Malaysia.
FAU - Tan, Siow Foon
AU  - Tan SF
AD  - Klinik Kesihatan Pelabuhan Klang, Ministry of Health Malaysia, Klang, Malaysia.
FAU - Omar, Azahadi
AU  - Omar A
AD  - National Institute of Health, Ministry of Health Malaysia, Setia Alam, Malaysia.
FAU - Nasir, Nazrila Hairizan
AU  - Nasir NH
AD  - Family Health Development Division, Ministry of Health Malaysia, Setia Alam, 
      Malaysia.
FAU - Ching, Siew Mooi
AU  - Ching SM
AD  - Department of Family Medicine, Faculty of Medicine and Health Sciences, 
      Universiti Putra Malaysia, Serdang, Malaysia.
AD  - Malaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, 
      Malaysia.
FAU - Mohd Noor, Mohd Khairi
AU  - Mohd Noor MK
AD  - Klinik Kesihatan Seksyen 7, Ministry of Health Malaysia, Shah Alam, Malaysia.
FAU - Masdor, Noor Azreen
AU  - Masdor NA
AD  - Department of Community Health, Faculty of Medicine, Universiti Kebangsaan 
      Malaysia, Cheras, Malaysia.
FAU - Lee, Yeow Siong
AU  - Lee YS
AD  - Klinik Kesihatan Selayang Baru, Ministry of Health Malaysia, Batu Caves, 
      Malaysia.
FAU - Noordin, Salmah
AU  - Noordin S
AD  - Klinik Kesihatan Cheras Batu 9, Ministry of Health Malaysia, Cheras, Malaysia.
FAU - Mohamed, Hazlin
AU  - Mohamed H
AD  - Klinik Kesihatan Teluk Panglima Garang, Ministry of Health Malaysia, Teluk 
      Panglima Garang, Malaysia.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20211012
PL  - England
TA  - Gynecol Endocrinol
JT  - Gynecological endocrinology : the official journal of the International Society 
      of Gynecological Endocrinology
JID - 8807913
RN  - Diabetes Mellitus, Noninsulin-Dependent, 2
SB  - IM
MH  - Counseling
MH  - Diabetes Mellitus, Type 2/epidemiology/*prevention & control
MH  - Diabetes, Gestational/physiopathology/*therapy
MH  - Diet Therapy
MH  - Exercise
MH  - Female
MH  - Gestational Age
MH  - Health Education
MH  - Humans
MH  - Metabolome
MH  - Nutritionists
MH  - Patient Education as Topic
MH  - Physical Therapists
MH  - Postpartum Period
MH  - Pregnancy
OTO - NOTNLM
OT  - Gestational diabetes mellitus
OT  - antenatal intervention
OT  - clinical trial
OT  - postpartum intervention
OT  - prevention of diabetes mellitus
EDAT- 2021/10/13 06:00
MHDA- 2022/03/19 06:00
CRDT- 2021/10/12 12:22
PHST- 2021/10/13 06:00 [pubmed]
PHST- 2022/03/19 06:00 [medline]
PHST- 2021/10/12 12:22 [entrez]
AID - 10.1080/09513590.2021.1988561 [doi]
PST - ppublish
SO  - Gynecol Endocrinol. 2022 Jan;38(1):55-62. doi: 10.1080/09513590.2021.1988561. 
      Epub 2021 Oct 12.