PMID- 34641143
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211016
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 13
IP  - 19
DP  - 2021 Sep 29
TI  - Anti-Demineralization Effects of Dental Adhesive-Composites on Enamel-Root Dentin 
      Junction.
LID - 10.3390/polym13193327 [doi]
LID - 3327
AB  - Oral biofilm reactor (OBR) and pH cycling (pHC) artificial caries model were 
      employed to evaluate the anti-demineralization effects of four composite filling 
      systems on enamel-root dentin junction. Sixty-four enamel-root dentin blocks (6 
      mm x 6 mm x 2 mm) each with a cylindrical cavity were randomly assigned to the 
      pHC and OBR group, then four subgroups (n = 8) and filled with either the 
      Beautifil II (BEF, SPRG-filler-containing) or Estelite (EST) composite after the 
      adhesive (either Single Bond Universal (SBU) or FL Bond II (FL, 
      SPRG-filler-containing)). The demineralization lesions of filling interface were 
      examined by micro-computerized tomography (muCT) and swept-source-optical 
      coherence tomography (SS-OCT). According to the degree of interface damage, the 
      caries lesions were sorted into four types: Type A and B (no attachment loss); 
      Type C and D (attachment loss). EST/SBU showed the worst demineralization lesion 
      and attachment loss (100% Type D), while BEF/FL exhibited the shallowest lesion 
      depth (p < 0.05, 145 +/- 45 mum on enamel, 275 +/- 35 mum on root dentin) and no 
      attachment loss (75% Type A and 25% Type B). Using FL adhesive alone does not 
      effectively reduce enamel demineralization. BEF plays a leading role in acid 
      resistance. The combination of BEF and FL showed a cumulative synergistic effect 
      on anti-demineralization.
FAU - Lai, Yu-Jung
AU  - Lai YJ
AD  - School of Dentistry, Graduate Institute of Clinical Dentistry, National Taiwan 
      University, Taipei 10048, Taiwan.
AD  - Dental Department, Division of Restorative and Aesthetic Dentistry, National 
      Taiwan University Hospital, Taipei 100229, Taiwan.
FAU - Takahashi, Rena
AU  - Takahashi R
AUID- ORCID: 0000-0002-3237-5515
AD  - Department of Cariology and Operative Dentistry, Division of Oral Health 
      Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and 
      Dental University, Tokyo 113-8549, Japan.
FAU - Lin, Po-Yen
AU  - Lin PY
AUID- ORCID: 0000-0002-8391-4558
AD  - Department of Dentistry, School of Dentistry, National Yang Ming Chiao Tung 
      University, Taipei 112, Taiwan.
FAU - Kuo, Ling
AU  - Kuo L
AD  - Dental Department, Division of Restorative and Aesthetic Dentistry, National 
      Taiwan University Hospital, Taipei 100229, Taiwan.
FAU - Zhou, Yuan
AU  - Zhou Y
AD  - Department of Cariology and Operative Dentistry, Division of Oral Health 
      Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and 
      Dental University, Tokyo 113-8549, Japan.
FAU - Matin, Khairul
AU  - Matin K
AD  - Department of Cariology and Operative Dentistry, Division of Oral Health 
      Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and 
      Dental University, Tokyo 113-8549, Japan.
FAU - Chiang, Yu-Chih
AU  - Chiang YC
AUID- ORCID: 0000-0001-8110-3033
AD  - School of Dentistry, Graduate Institute of Clinical Dentistry, National Taiwan 
      University, Taipei 10048, Taiwan.
AD  - Dental Department, Division of Restorative and Aesthetic Dentistry, National 
      Taiwan University Hospital, Taipei 100229, Taiwan.
AD  - Molecular Imaging Center, National Taiwan University, Taipei 10617, Taiwan.
FAU - Shimada, Yasushi
AU  - Shimada Y
AD  - Department of Cariology and Operative Dentistry, Division of Oral Health 
      Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and 
      Dental University, Tokyo 113-8549, Japan.
FAU - Tagami, Junji
AU  - Tagami J
AD  - Department of Cariology and Operative Dentistry, Division of Oral Health 
      Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and 
      Dental University, Tokyo 113-8549, Japan.
LA  - eng
GR  - 108-S4431/National Taiwan University Hospital/
GR  - MOST 109-2314-B-002-041-MY3 and 110-2314-B-002 -108 -MY3/Ministry of Science and 
      Technology of Taiwan/
PT  - Journal Article
DEP - 20210929
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC8512347
OTO - NOTNLM
OT  - 10-MDP
OT  - SPRG-filler
OT  - adhesive composite
OT  - micro-CT
OT  - oral biofilm reactor
OT  - swept-source-OCT
COIS- The authors declare no conflict of interest. The funders had no role in the 
      design of the study; in the collection, analyses, or interpretation of data; in 
      the writing of the manuscript, or in the decision to publish the results.
EDAT- 2021/10/14 06:00
MHDA- 2021/10/14 06:01
PMCR- 2021/09/29
CRDT- 2021/10/13 01:13
PHST- 2021/09/06 00:00 [received]
PHST- 2021/09/26 00:00 [revised]
PHST- 2021/09/26 00:00 [accepted]
PHST- 2021/10/13 01:13 [entrez]
PHST- 2021/10/14 06:00 [pubmed]
PHST- 2021/10/14 06:01 [medline]
PHST- 2021/09/29 00:00 [pmc-release]
AID - polym13193327 [pii]
AID - polymers-13-03327 [pii]
AID - 10.3390/polym13193327 [doi]
PST - epublish
SO  - Polymers (Basel). 2021 Sep 29;13(19):3327. doi: 10.3390/polym13193327.