PMID- 34645262
OWN - NLM
STAT- MEDLINE
DCOM- 20211101
LR  - 20211101
IS  - 1520-6882 (Electronic)
IS  - 0003-2700 (Print)
IS  - 0003-2700 (Linking)
VI  - 93
IP  - 42
DP  - 2021 Oct 26
TI  - Revealing Contamination and Sequence of Overlapping Fingerprints by Unsupervised 
      Treatment of a Hyperspectral Secondary Ion Mass Spectrometry Dataset.
PG  - 14099-14105
LID - 10.1021/acs.analchem.1c01981 [doi]
AB  - Time-of-flight secondary ion mass spectrometry (ToF-SIMS) has been successfully 
      applied for chemical imaging of overlapping fingermarks. The resulting big 
      dataset has been treated by means of an unsupervised machine learning approach 
      based on uniform manifold approximation and projection. The hyperspectral matrix 
      was composed of 49 million pixels associated with 518 peaks. However, the 
      single-pixel spectrum results in a very poor signal intensity, mostly like a 
      barcode. Contrary to what has been reported in the literature recently, we have 
      not applied a crude approach based on binning but a sophisticated machine 
      learning method capable of separating the chemical signals of the two 
      fingerprints from each other and from the substrate in which they were impressed. 
      Moreover, using ToF-SIMS, an extremely surface-sensitive technique, the sequence 
      of deposition of the fingerprints has been determined.
FAU - Tuccitto, Nunzio
AU  - Tuccitto N
AUID- ORCID: 0000-0003-4129-0406
AD  - Consorzio per lo Sviluppo dei Sistemi a Grande Interfase, CSGI, Viale A. Doria 6, 
      95125 Catania, Italy.
AD  - Department of Chemical Sciences, Universita degli Studi di Catania, Viale A. 
      Doria 6, 95125 Catania, Italy.
FAU - Bombace, Alessandra
AU  - Bombace A
AD  - Department of Chemical Sciences, Universita degli Studi di Catania, Viale A. 
      Doria 6, 95125 Catania, Italy.
FAU - Auditore, Alessandro
AU  - Auditore A
AD  - Department of Chemical Sciences, Universita degli Studi di Catania, Viale A. 
      Doria 6, 95125 Catania, Italy.
FAU - Valenti, Andrea
AU  - Valenti A
AUID- ORCID: 0000-0001-8645-3331
AD  - Consorzio per lo Sviluppo dei Sistemi a Grande Interfase, CSGI, Viale A. Doria 6, 
      95125 Catania, Italy.
FAU - Torrisi, Alberto
AU  - Torrisi A
AUID- ORCID: 0000-0002-0940-7750
AD  - Department of Chemical Sciences, Universita degli Studi di Catania, Viale A. 
      Doria 6, 95125 Catania, Italy.
FAU - Capizzi, Giacomo
AU  - Capizzi G
AD  - Electrical, Electronic and Computer Engineering, Universita degli Studi di 
      Catania, Viale A. Doria 6, 95125 Catania, Italy.
FAU - Licciardello, Antonino
AU  - Licciardello A
AUID- ORCID: 0000-0001-5146-8971
AD  - Consorzio per lo Sviluppo dei Sistemi a Grande Interfase, CSGI, Viale A. Doria 6, 
      95125 Catania, Italy.
AD  - Department of Chemical Sciences, Universita degli Studi di Catania, Viale A. 
      Doria 6, 95125 Catania, Italy.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20211013
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
SB  - IM
MH  - *Machine Learning
MH  - *Spectrometry, Mass, Secondary Ion
PMC - PMC8552212
COIS- The authors declare no competing financial interest.
EDAT- 2021/10/15 06:00
MHDA- 2021/11/03 06:00
PMCR- 2021/10/28
CRDT- 2021/10/14 05:22
PHST- 2021/10/15 06:00 [pubmed]
PHST- 2021/11/03 06:00 [medline]
PHST- 2021/10/14 05:22 [entrez]
PHST- 2021/10/28 00:00 [pmc-release]
AID - 10.1021/acs.analchem.1c01981 [doi]
PST - ppublish
SO  - Anal Chem. 2021 Oct 26;93(42):14099-14105. doi: 10.1021/acs.analchem.1c01981. 
      Epub 2021 Oct 13.