PMID- 34651702
OWN - NLM
STAT- MEDLINE
DCOM- 20220105
LR  - 20220105
IS  - 1346-8138 (Electronic)
IS  - 0385-2407 (Linking)
VI  - 49
IP  - 1
DP  - 2022 Jan
TI  - Cutaneous manifestations and dermoscopic findings are important clues to the 
      diagnosis of Talaromyces marneffei in HIV patients with immune reconstitution 
      inflammatory syndrome: A case report and literature review.
PG  - 168-172
LID - 10.1111/1346-8138.16197 [doi]
AB  - Talaromyces (formerly Penicillium) marneffei is a dimorphic fungus that causes 
      talaromycosis (formerly penicilliosis). The condition is predominantly found in 
      patients with HIV. Important diagnostic clues are a history of living or 
      travelling in endemic areas, and central umbilicated skin lesions. Dermoscopy is 
      particularly useful for providing rapid bedside information, with a round, 
      whitish, amorphous structure being the most common finding. Immune reconstitution 
      inflammatory syndrome (IRIS) may occur. Driven by the initiation of 
      antiretroviral therapy, IRIS is an exaggerated response of T cells to pathogens. 
      Although mycobacterial and cryptococcal opportunistic infections are common with 
      IRIS, a linkage between T. marneffei and IRIS has rarely been reported. Here, we 
      report on a literature review of patients with HIV who developed IRIS associated 
      with talaromycosis. Dermatologists should be aware of the cutaneous and 
      dermoscopic findings of talaromycosis as they provide important clues that enable 
      its early diagnosis and treatment.
CI  - (c) 2021 Japanese Dermatological Association.
FAU - Chaisuwannarak, Kornkanok
AU  - Chaisuwannarak K
AUID- ORCID: 0000-0002-5609-6203
AD  - Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol 
      University, Bangkok, Thailand.
FAU - Chularojanamontri, Leena
AU  - Chularojanamontri L
AUID- ORCID: 0000-0001-6625-6445
AD  - Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol 
      University, Bangkok, Thailand.
FAU - Junsuwan, Natachaya
AU  - Junsuwan N
AUID- ORCID: 0000-0002-0421-7106
AD  - Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol 
      University, Bangkok, Thailand.
FAU - Eimpunth, Sasima
AU  - Eimpunth S
AUID- ORCID: 0000-0003-4843-0459
AD  - Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol 
      University, Bangkok, Thailand.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20211015
PL  - England
TA  - J Dermatol
JT  - The Journal of dermatology
JID - 7600545
RN  - 0 (Antifungal Agents)
RN  - Talaromyces marneffei
SB  - IM
MH  - Antifungal Agents/therapeutic use
MH  - *HIV Infections/complications/drug therapy
MH  - Humans
MH  - *Immune Reconstitution Inflammatory Syndrome/diagnosis
MH  - *Mycoses/drug therapy
MH  - *Talaromyces
OTO - NOTNLM
OT  - Talaromyces marneffei
OT  - dermoscopy
OT  - immune reconstitution inflammatory syndrome
OT  - round whitish amorphous structure
OT  - umbilicated lesion
EDAT- 2021/10/16 06:00
MHDA- 2022/01/06 06:00
CRDT- 2021/10/15 08:46
PHST- 2021/09/28 00:00 [revised]
PHST- 2021/07/25 00:00 [received]
PHST- 2021/10/01 00:00 [accepted]
PHST- 2021/10/16 06:00 [pubmed]
PHST- 2022/01/06 06:00 [medline]
PHST- 2021/10/15 08:46 [entrez]
AID - 10.1111/1346-8138.16197 [doi]
PST - ppublish
SO  - J Dermatol. 2022 Jan;49(1):168-172. doi: 10.1111/1346-8138.16197. Epub 2021 Oct 
      15.