PMID- 34654253
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211018
IS  - 1878-7649 (Print)
IS  - 1878-7649 (Linking)
VI  - 9
IP  - 2
DP  - 2018 Apr
TI  - Bone mineral density in older patients with chronic heart failure is related to 
      NYHA classification: a retrospective study.
PG  - 183-189
LID - 10.1007/s41999-018-0027-5 [doi]
AB  - PURPOSE: Discrepant results on relationship between chronic heart failure (CHF) 
      and bone mineral density (BMD) have been reported and little has investigated the 
      association between bone mass loss and New York Heart Association (NYHA) 
      classification in CHF patients. This study aimed to assess whether BMD was 
      associated with NYHA classification in older CHF patients. METHODS: It was a 
      retrospective study and included 1049 stable CHF patients aged over 60 years in 
      Zhejiang Hospital. BMD and T-score at femoral neck (FN) and lumbar spines over 
      L2-L4 regions were measured using Dual-Energy X-ray Absorptiometry. One-way ANOVA 
      was used to compare continuous data of different NYHA functional class. 
      Categorical variables were compared by Chi-square analysis. Pearson or Spearman 
      correlation test was used to analyze the association between BMD and NYHA class, 
      clinical parameters, lab data, etc. Significant variables in the correlation test 
      (P < 0.05) were then tested by a multivariate linear regression test with 
      stepwise subset selection to identify independent factors predicting BMD. 
      RESULTS: There were significant differences in FN BMD and T score across NYHA 
      class I-IV, and that L2-L4 BMD and T score in patients in NYHA class IV were 
      significantly lower when compared with CHF participants in NYHA classes I, II, 
      and III. Moreover, Pearson correlation test and multivariate linear regression 
      test demonstrated that there were statistically significant correlations between 
      bone densitometric parameters and NYHA class. CONCLUSIONS: There was a 
      significant correlation between BMD and T-score at lumbar spines over L2-L4 and 
      FN and NYHA class, implying that early screening and comprehensive intervention 
      for osteoporosis (OP) might be helpful for patients with CHF.
CI  - (c) 2018. European Geriatric Medicine Society.
FAU - Fang, Yefei
AU  - Fang Y
AD  - Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
AD  - Yuyao People's Hospital, The Affiliated Yangming Hospital, Ningbo, 315400, 
      Zhejiang, China.
FAU - Wang, Liping
AU  - Wang L
AD  - Department of Pulmonary Disease, The Affiliated Hospital of Hangzhou Normal 
      University, Hangzhou, 310014, Zhejiang, China.
FAU - Xing, Wenmin
AU  - Xing W
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China.
FAU - Wu, Qing
AU  - Wu Q
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China.
FAU - Tong, Qian
AU  - Tong Q
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China.
FAU - Yu, Yanbo
AU  - Yu Y
AD  - Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
FAU - Lv, Xiaoling
AU  - Lv X
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China.
FAU - Wang, Bozhong
AU  - Wang B
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China.
FAU - Wang, Guofu
AU  - Wang G
AD  - Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. 1090983005@qq.com.
AD  - Department of Geriatrics, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, 
      Zhejiang, China. 1090983005@qq.com.
LA  - eng
GR  - 31670701/National Natural Science Foundation of China/
GR  - Y15H050018/Natural Science Foundation of Zhejiang Province/
PT  - Journal Article
DEP - 20180118
PL  - Switzerland
TA  - Eur Geriatr Med
JT  - European geriatric medicine
JID - 101533694
SB  - IM
OTO - NOTNLM
OT  - Bone mineral density
OT  - Chronic heart failure
OT  - New York heart association
OT  - Osteopenia
OT  - Osteoporosis
EDAT- 2018/04/01 00:00
MHDA- 2018/04/01 00:01
CRDT- 2021/10/16 01:01
PHST- 2017/11/09 00:00 [received]
PHST- 2018/01/09 00:00 [accepted]
PHST- 2021/10/16 01:01 [entrez]
PHST- 2018/04/01 00:00 [pubmed]
PHST- 2018/04/01 00:01 [medline]
AID - 10.1007/s41999-018-0027-5 [pii]
AID - 10.1007/s41999-018-0027-5 [doi]
PST - ppublish
SO  - Eur Geriatr Med. 2018 Apr;9(2):183-189. doi: 10.1007/s41999-018-0027-5. Epub 2018 
      Jan 18.